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1.
Fyn Kinase Regulates Microglial Neuroinflammatory Responses in Cell Culture and Animal Models of Parkinson's Disease.
J Neurosci
; 35(27): 10058-77, 2015 Jul 08.
Artículo
en Inglés
| MEDLINE | ID: mdl-26157004
2.
The peptidyl-prolyl isomerase Pin1 up-regulation and proapoptotic function in dopaminergic neurons: relevance to the pathogenesis of Parkinson disease.
J Biol Chem
; 288(30): 21955-71, 2013 Jul 26.
Artículo
en Inglés
| MEDLINE | ID: mdl-23754278
3.
Pharmacological Inhibition of PTEN Rescues Dopaminergic Neurons by Attenuating Apoptotic and Neuroinflammatory Signaling Events.
J Neuroimmune Pharmacol
; 18(3): 462-475, 2023 09.
Artículo
en Inglés
| MEDLINE | ID: mdl-37589761
4.
Environmental neurotoxicants and inflammasome activation in Parkinson's disease - A focus on the gut-brain axis.
Int J Biochem Cell Biol
; 142: 106113, 2022 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-34737076
5.
Discovery and Optimization of Biaryl Alkyl Ethers as a Novel Class of Highly Selective, CNS-Penetrable, and Orally Active Adaptor Protein-2-Associated Kinase 1 (AAK1) Inhibitors for the Potential Treatment of Neuropathic Pain.
J Med Chem
; 65(6): 4534-4564, 2022 03 24.
Artículo
en Inglés
| MEDLINE | ID: mdl-35261239
6.
Discovery of (S)-1-((2',6-Bis(difluoromethyl)-[2,4'-bipyridin]-5-yl)oxy)-2,4-dimethylpentan-2-amine (BMS-986176/LX-9211): A Highly Selective, CNS Penetrable, and Orally Active Adaptor Protein-2 Associated Kinase 1 Inhibitor in Clinical Trials for the Treatment of Neuropathic Pain.
J Med Chem
; 65(6): 4457-4480, 2022 03 24.
Artículo
en Inglés
| MEDLINE | ID: mdl-35257579
7.
Perspectives on the use and risk of adverse events associated with cytokine-storm targeting antibodies and challenges associated with development of novel monoclonal antibodies for the treatment of COVID-19 clinical cases.
Hum Vaccin Immunother
; 17(9): 2824-2840, 2021 09 02.
Artículo
en Inglés
| MEDLINE | ID: mdl-33974497
8.
Fyn Kinase-Mediated PKCδ Y311 Phosphorylation Induces Dopaminergic Degeneration in Cell Culture and Animal Models: Implications for the Identification of a New Pharmacological Target for Parkinson's Disease.
Front Pharmacol
; 12: 631375, 2021.
Artículo
en Inglés
| MEDLINE | ID: mdl-33995031
9.
Fyn kinase mediates pro-inflammatory response in a mouse model of endotoxemia: Relevance to translational research.
Eur J Pharmacol
; 881: 173259, 2020 Aug 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-32565338
10.
Fyn kinase regulates misfolded α-synuclein uptake and NLRP3 inflammasome activation in microglia.
J Exp Med
; 216(6): 1411-1430, 2019 06 03.
Artículo
en Inglés
| MEDLINE | ID: mdl-31036561
11.
Protein kinase D1 (PKD1) activation mediates a compensatory protective response during early stages of oxidative stress-induced neuronal degeneration.
Mol Neurodegener
; 6: 43, 2011 Jun 22.
Artículo
en Inglés
| MEDLINE | ID: mdl-21696630
12.
Environmental neurotoxic pesticide dieldrin activates a non receptor tyrosine kinase to promote PKCδ-mediated dopaminergic apoptosis in a dopaminergic neuronal cell model.
Neurotoxicology
; 32(5): 567-77, 2011 Oct.
Artículo
en Inglés
| MEDLINE | ID: mdl-21801747
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