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1.
Molecular Investigation of the Mechanism of Non-Enzymatic Hydrolysis of Proteins and the Predictive Algorithm for Susceptibility.
Biochemistry
; 55(23): 3315-28, 2016 06 14.
Artículo
en Inglés
| MEDLINE | ID: mdl-27194363
2.
Effects of salts from the Hofmeister series on the conformational stability, aggregation propensity, and local flexibility of an IgG1 monoclonal antibody.
Biochemistry
; 52(19): 3376-89, 2013 May 14.
Artículo
en Inglés
| MEDLINE | ID: mdl-23594236
3.
Advancements in high throughput biophysical technologies: applications for characterization and screening during early formulation development of monoclonal antibodies.
Mol Pharm
; 9(4): 696-707, 2012 Apr 02.
Artículo
en Inglés
| MEDLINE | ID: mdl-22263524
4.
Preferential interactions of trehalose, L-arginine.HCl and sodium chloride with therapeutically relevant IgG1 monoclonal antibodies.
MAbs
; 9(7): 1155-1168, 2017 10.
Artículo
en Inglés
| MEDLINE | ID: mdl-28758834
5.
Utility of High Throughput Screening Techniques to Predict Stability of Monoclonal Antibody Formulations During Early Stage Development.
J Pharm Sci
; 106(8): 1971-1977, 2017 08.
Artículo
en Inglés
| MEDLINE | ID: mdl-28456733
6.
Computational tool for the early screening of monoclonal antibodies for their viscosities.
MAbs
; 8(1): 43-8, 2016.
Artículo
en Inglés
| MEDLINE | ID: mdl-26399600
7.
Hydrogen exchange mass spectrometry reveals protein interfaces and distant dynamic coupling effects during the reversible self-association of an IgG1 monoclonal antibody.
MAbs
; 7(3): 525-39, 2015.
Artículo
en Inglés
| MEDLINE | ID: mdl-25875351
8.
Correlations between changes in conformational dynamics and physical stability in a mutant IgG1 mAb engineered for extended serum half-life.
MAbs
; 7(1): 84-95, 2015.
Artículo
en Inglés
| MEDLINE | ID: mdl-25524268
9.
A systematic multitechnique approach for detection and characterization of reversible self-association during formulation development of therapeutic antibodies.
J Pharm Sci
; 102(1): 62-72, 2013 Jan.
Artículo
en Inglés
| MEDLINE | ID: mdl-23150484
10.
A systematic multitechnique approach for detection and characterization of reversible self-association during formulation development of therapeutic antibodies.
J Pharm Sci
; 102(9): 3089-99, 2013 Sep.
Artículo
en Inglés
| MEDLINE | ID: mdl-23794522
11.
Correlating excipient effects on conformational and storage stability of an IgG1 monoclonal antibody with local dynamics as measured by hydrogen/deuterium-exchange mass spectrometry.
J Pharm Sci
; 102(7): 2136-51, 2013 Jul.
Artículo
en Inglés
| MEDLINE | ID: mdl-23620222
12.
Local dynamics and their alteration by excipients modulate the global conformational stability of an lgG1 monoclonal antibody.
J Pharm Sci
; 101(12): 4444-57, 2012 Dec.
Artículo
en Inglés
| MEDLINE | ID: mdl-23060088
13.
The effects of substituted cyclodextrins on the colloidal and conformational stability of selected proteins.
J Pharm Sci
; 99(6): 2800-18, 2010 Jun.
Artículo
en Inglés
| MEDLINE | ID: mdl-20049940
14.
Biophysical and stabilization studies of the Chlamydia trachomatis mouse pneumonitis major outer membrane protein.
Mol Pharm
; 6(5): 1553-61, 2009.
Artículo
en Inglés
| MEDLINE | ID: mdl-19650664
15.
The role of specific beta-gamma subunit interactions in oxyanion stimulation of the MgATP hydrolysis of a hybrid photosynthetic F1-ATPase.
J Bioenerg Biomembr
; 40(2): 69-76, 2008 Apr.
Artículo
en Inglés
| MEDLINE | ID: mdl-18415008
16.
C-Terminal mutations in the chloroplast ATP synthase gamma subunit impair ATP synthesis and stimulate ATP hydrolysis.
Biochemistry
; 47(2): 836-44, 2008 Jan 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-18092810
17.
Mutations within the C-terminus of the gamma subunit of the photosynthetic F1-ATPase activate MgATP hydrolysis and attenuate the stimulatory oxyanion effect.
Biochemistry
; 46(9): 2411-8, 2007 Mar 06.
Artículo
en Inglés
| MEDLINE | ID: mdl-17288458
18.
Structural analysis of the regulatory dithiol-containing domain of the chloroplast ATP synthase gamma subunit.
J Biol Chem
; 281(41): 31041-9, 2006 Oct 13.
Artículo
en Inglés
| MEDLINE | ID: mdl-16895914
19.
Ectoadenylate kinase and plasma membrane ATP synthase activities of human vascular endothelial cells.
J Biol Chem
; 281(30): 20728-20737, 2006 Jul 28.
Artículo
en Inglés
| MEDLINE | ID: mdl-16714292
20.
Coupling proton movement to ATP synthesis in the chloroplast ATP synthase.
J Bioenerg Biomembr
; 37(6): 467-73, 2005 Dec.
Artículo
en Inglés
| MEDLINE | ID: mdl-16691485
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