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1.
Discovery and optimization of Lu AF58801, a novel, selective and brain penetrant positive allosteric modulator of alpha-7 nicotinic acetylcholine receptors: attenuation of subchronic phencyclidine (PCP)-induced cognitive deficits in rats following oral administration.
Bioorg Med Chem Lett
; 24(1): 288-93, 2014 Jan 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-24291041
2.
The novel adenosine A2A antagonist Lu AA47070 reverses the motor and motivational effects produced by dopamine D2 receptor blockade.
Pharmacol Biochem Behav
; 100(3): 498-505, 2012 Jan.
Artículo
en Inglés
| MEDLINE | ID: mdl-22037410
3.
Discovery of phosphoric acid mono-{2-[(E/Z)-4-(3,3-dimethyl-butyrylamino)-3,5-difluoro-benzoylimino]-thiazol-3-ylmethyl} ester (Lu AA47070): a phosphonooxymethylene prodrug of a potent and selective hA(2A) receptor antagonist.
J Med Chem
; 54(3): 751-64, 2011 Feb 10.
Artículo
en Inglés
| MEDLINE | ID: mdl-21210664
4.
Discovery of N-{1-[3-(3-oxo-2,3-dihydrobenzo[1,4]oxazin-4-yl)propyl]piperidin-4-yl}-2-phenylacetamide (Lu AE51090): an allosteric muscarinic M1 receptor agonist with unprecedented selectivity and procognitive potential.
J Med Chem
; 53(17): 6386-97, 2010 Sep 09.
Artículo
en Inglés
| MEDLINE | ID: mdl-20684563
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