Detalles de la búsqueda
1.
Biocatalysis using Thermostable Cytochrome P450 Enzymes in Bacterial Membranes - Comparison of Metabolic Pathways with Human Liver Microsomes and Recombinant Human Enzymes.
Drug Metab Dispos
; 52(3): 242-251, 2024 Feb 14.
Artículo
en Inglés
| MEDLINE | ID: mdl-38176735
2.
Ancestral Sequence Reconstruction of a Cytochrome P450 Family Involved in Chemical Defense Reveals the Functional Evolution of a Promiscuous, Xenobiotic-Metabolizing Enzyme in Vertebrates.
Mol Biol Evol
; 39(6)2022 06 02.
Artículo
en Inglés
| MEDLINE | ID: mdl-35639613
3.
Biotransformation of the Novel Myeloperoxidase Inhibitor AZD4831 in Preclinical Species and Humans.
Drug Metab Dispos
; 51(4): 464-479, 2023 04.
Artículo
en Inglés
| MEDLINE | ID: mdl-36653117
4.
Application of Accelerator Mass Spectrometry to Characterize the Mass Balance Recovery and Disposition of AZD4831, a Novel Myeloperoxidase Inhibitor, following Administration of an Oral Radiolabeled Microtracer Dose in Humans.
Drug Metab Dispos
; 51(4): 451-463, 2023 04.
Artículo
en Inglés
| MEDLINE | ID: mdl-36639243
5.
Structural and functional characterization of a specific antidote for ticagrelor.
Blood
; 125(22): 3484-90, 2015 May 28.
Artículo
en Inglés
| MEDLINE | ID: mdl-25788700
6.
Inhibition of SGLT2 Preserves Function and Promotes Proliferation of Human Islets Cells In Vivo in Diabetic Mice.
Biomedicines
; 10(2)2022 Jan 18.
Artículo
en Inglés
| MEDLINE | ID: mdl-35203411
7.
Functionalized lipid nanoparticles for subcutaneous administration of mRNA to achieve systemic exposures of a therapeutic protein.
Mol Ther Nucleic Acids
; 24: 369-384, 2021 Jun 04.
Artículo
en Inglés
| MEDLINE | ID: mdl-33868782
8.
Developing an injectable co-formulation of two antidiabetic drugs: Excipient impact on peptide aggregation and pharmacokinetic properties.
Int J Pharm
; 576: 119019, 2020 Feb 25.
Artículo
en Inglés
| MEDLINE | ID: mdl-31911116
9.
Quantification of unbound concentration of ticagrelor in plasma as a proof of mechanism biomarker of the reversal agent, MEDI2452.
PLoS One
; 13(7): e0201202, 2018.
Artículo
en Inglés
| MEDLINE | ID: mdl-30048515
Resultados
1 -
9
de 9
1
Próxima >
>>