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1.
Selective activation of PFKL suppresses the phagocytic oxidative burst.
Cell
; 184(17): 4480-4494.e15, 2021 08 19.
Artículo
en Inglés
| MEDLINE | ID: mdl-34320407
2.
Blockade of the Phagocytic Receptor MerTK on Tumor-Associated Macrophages Enhances P2X7R-Dependent STING Activation by Tumor-Derived cGAMP.
Immunity
; 52(2): 357-373.e9, 2020 02 18.
Artículo
en Inglés
| MEDLINE | ID: mdl-32049051
3.
Structure of the essential inner membrane lipopolysaccharide-PbgA complex.
Nature
; 584(7821): 479-483, 2020 08.
Artículo
en Inglés
| MEDLINE | ID: mdl-32788728
4.
High-Throughput, Nondestructive, and Biosafe Method to Accurately Quantify Water Content in Human Fecal Samples by Benchtop 1H TD-NMR Analysis for Downstream Bioanalytical and Clinical Uses.
Anal Chem
; 96(9): 3722-3726, 2024 Mar 05.
Artículo
en Inglés
| MEDLINE | ID: mdl-38373266
5.
Comparative Impact of Various Fasting Periods on the Welfare of Sprague-Dawley Rats With or Without Supplementation.
Toxicol Pathol
; 52(1): 21-34, 2024 Jan.
Artículo
en Inglés
| MEDLINE | ID: mdl-38379371
6.
Analysis of the Bile Acid Composition in a Fibroblast Growth Factor 19-Expressing Liver-Humanized Mouse Model and Its Use for CYP3A4-Mediated Drug-Drug Interaction Studies.
Drug Metab Dispos
; 51(10): 1391-1402, 2023 10.
Artículo
en Inglés
| MEDLINE | ID: mdl-37524541
7.
Glycochenodeoxycholate and glycodeoxycholate 3-O-glucuronides, but not hexadecanedioate and tetradecanedioate, detected weak inhibition of OATP1B caused by GDC-0810 in humans.
Br J Clin Pharmacol
; 89(6): 1903-1907, 2023 06.
Artículo
en Inglés
| MEDLINE | ID: mdl-36735594
8.
Reduced Fasting Duration in Cynomolgus Monkeys Enhances Animal Welfare During Toxicology Studies.
Toxicol Pathol
; 51(5): 264-277, 2023 07.
Artículo
en Inglés
| MEDLINE | ID: mdl-37702042
9.
Establishment of baseline profiles of 50 bile acids in preclinical toxicity species: A comprehensive assessment of translational differences and study design considerations for biomarker development.
Toxicol Appl Pharmacol
; 443: 116008, 2022 05 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-35378153
10.
LC-HRMS-based targeted metabolomics for high-throughput and quantitative analysis of 21 growth inhibition-related metabolites in Chinese hamster ovary cell fed-batch cultures.
Biomed Chromatogr
; 36(5): e5348, 2022 May.
Artículo
en Inglés
| MEDLINE | ID: mdl-35083760
11.
A Novel Depurination Methodology to Assess DNA Alkylation of Chloro-Bis-Seco-Cyclopropylbenzoindoles Allowed for Comparison of Minor-Groove Reactivity.
Drug Metab Dispos
; 47(5): 547-555, 2019 05.
Artículo
en Inglés
| MEDLINE | ID: mdl-30858239
12.
Comprehensive Evaluation of Bile Acid Homeostasis in Human Hepatocyte Co-Culture in the Presence of Troglitazone, Pioglitazone, and Acetylsalicylic Acid.
Mol Pharm
; 16(10): 4230-4240, 2019 10 07.
Artículo
en Inglés
| MEDLINE | ID: mdl-31509422
13.
Sex-specific differences in genotoxic and epigenetic effects of 1,3-butadiene among mouse tissues.
Arch Toxicol
; 93(3): 791-800, 2019 03.
Artículo
en Inglés
| MEDLINE | ID: mdl-30552462
14.
N6-(2-Deoxy-d- erythro-pentofuranosyl)-2,6-diamino-3,4-dihydro-4-oxo-5- N-(2-hydroxy-3-buten-1-yl)-formamidopyrimidine Adducts of 1,3-Butadiene: Synthesis, Structural Identification, and Detection in Human Cells.
Chem Res Toxicol
; 31(9): 885-897, 2018 09 17.
Artículo
en Inglés
| MEDLINE | ID: mdl-30016111
15.
Isotope Dilution nanoLC/ESI+-HRMS3 Quantitation of Urinary N7-(1-Hydroxy-3-buten-2-yl) Guanine Adducts in Humans and Their Use as Biomarkers of Exposure to 1,3-Butadiene.
Chem Res Toxicol
; 30(2): 678-688, 2017 02 20.
Artículo
en Inglés
| MEDLINE | ID: mdl-27997139
16.
Cellular Repair of DNA-DNA Cross-Links Induced by 1,2,3,4-Diepoxybutane.
Int J Mol Sci
; 18(5)2017 May 18.
Artículo
en Inglés
| MEDLINE | ID: mdl-28524082
17.
Bis-butanediol-mercapturic acid (bis-BDMA) as a urinary biomarker of metabolic activation of butadiene to its ultimate carcinogenic species.
Carcinogenesis
; 35(6): 1371-8, 2014 Jun.
Artículo
en Inglés
| MEDLINE | ID: mdl-24531806
18.
Strategies to improve CHO cell culture performance: Targeted deletion of amino acid catabolism and apoptosis genes paired with growth inhibitor supplementation.
Biotechnol Prog
; : e3471, 2024 Apr 17.
Artículo
en Inglés
| MEDLINE | ID: mdl-38629737
19.
Capillary HPLC-accurate mass MS/MS quantitation of N7-(2,3,4-trihydroxybut-1-yl)-guanine adducts of 1,3-butadiene in human leukocyte DNA.
Chem Res Toxicol
; 26(10): 1486-97, 2013 Oct 21.
Artículo
en Inglés
| MEDLINE | ID: mdl-23937706
20.
IL-22 alters gut microbiota composition and function to increase aryl hydrocarbon receptor activity in mice and humans.
Microbiome
; 11(1): 47, 2023 03 09.
Artículo
en Inglés
| MEDLINE | ID: mdl-36894983