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1.
Prediction of Oral Drug Absorption in Rats from In Vitro Data.
Pharm Res
; 40(2): 359-373, 2023 Feb.
Artículo
en Inglés
| MEDLINE | ID: mdl-35169960
2.
Empagliflozin as adjunct to insulin in Japanese participants with type 1 diabetes: Results of a 4-week, double-blind, randomized, placebo-controlled phase 2 trial.
Diabetes Obes Metab
; 20(9): 2190-2199, 2018 09.
Artículo
en Inglés
| MEDLINE | ID: mdl-29766633
3.
Population pharmacokinetic/pharmacodynamic analysis of the DPP-4 inhibitor linagliptin in Japanese patients with type 2 diabetes mellitus.
J Pharm Pharm Sci
; 16(5): 708-21, 2013.
Artículo
en Inglés
| MEDLINE | ID: mdl-24393553
4.
Phase I study of the VEGF/Ang-2 inhibitor BI 836880 alone or combined with the anti-programmed cell death protein-1 antibody ezabenlimab in Japanese patients with advanced solid tumors.
Cancer Chemother Pharmacol
; 91(6): 469-480, 2023 06.
Artículo
en Inglés
| MEDLINE | ID: mdl-37140602
5.
Population pharmacokinetics of tamsulosin hydrochloride in paediatric patients with neuropathic and non-neuropathic bladder.
Br J Clin Pharmacol
; 70(1): 88-101, 2010 Jul.
Artículo
en Inglés
| MEDLINE | ID: mdl-20642551
6.
Physiologically Based Pharmacokinetic Model of the DPP-4 Inhibitor Linagliptin to Describe its Nonlinear Pharmacokinetics in Humans.
J Pharm Sci
; 109(7): 2336-2344, 2020 07.
Artículo
en Inglés
| MEDLINE | ID: mdl-32283067
7.
Prediction Characteristics of Oral Absorption Simulation Software Evaluated Using Structurally Diverse Low-Solubility Drugs.
J Pharm Sci
; 109(3): 1403-1416, 2020 03.
Artículo
en Inglés
| MEDLINE | ID: mdl-31863733
8.
Phase I Study of the Focal Adhesion Kinase Inhibitor BI 853520 in Japanese and Taiwanese Patients with Advanced or Metastatic Solid Tumors.
Target Oncol
; 14(1): 57-65, 2019 02.
Artículo
en Inglés
| MEDLINE | ID: mdl-30725402
9.
An open-label feasibility study of nintedanib combined with docetaxel in Japanese patients with locally advanced or metastatic lung adenocarcinoma after failure of first-line chemotherapy.
Cancer Chemother Pharmacol
; 82(4): 685-694, 2018 10.
Artículo
en Inglés
| MEDLINE | ID: mdl-30073583
10.
Comparable pharmacodynamics, efficacy, and safety of linagliptin 5 mg among Japanese, Asian and white patients with type 2 diabetes.
J Diabetes Investig
; 7(5): 744-50, 2016 Sep.
Artículo
en Inglés
| MEDLINE | ID: mdl-27180969
11.
Phase I trial of afatinib plus vinorelbine in Japanese patients with advanced solid tumors, including breast cancer.
Cancer Chemother Pharmacol
; 76(4): 739-50, 2015 Oct.
Artículo
en Inglés
| MEDLINE | ID: mdl-26254023
12.
Phase I study of nintedanib in combination with pemetrexed as second-line treatment of Japanese patients with advanced non-small cell lung cancer.
Cancer Chemother Pharmacol
; 76(6): 1225-33, 2015 Dec.
Artículo
en Inglés
| MEDLINE | ID: mdl-26560486
13.
Tolerability of nintedanib (BIBF 1120) in combination with docetaxel: a phase 1 study in Japanese patients with previously treated non-small-cell lung cancer.
J Thorac Oncol
; 10(2): 346-52, 2015 Feb.
Artículo
en Inglés
| MEDLINE | ID: mdl-25299232
14.
Relationship between pharmacokinetic parameters and occurrence of adverse events in clinical trials performed in Europe and United States for an angiotensin II receptor antagonist, telmisartan.
Drug Metab Pharmacokinet
; 19(1): 24-32, 2004 Feb.
Artículo
en Inglés
| MEDLINE | ID: mdl-15499166
15.
Population pharmacokinetics of an angiotensin II receptor antagonist, telmisartan, in healthy volunteers and hypertensive patients.
Drug Metab Pharmacokinet
; 18(3): 203-11, 2003.
Artículo
en Inglés
| MEDLINE | ID: mdl-15618736
16.
Pharmacokinetic comparison of an angiotensin II receptor antagonist, telmisartan, in Japanese and western hypertensive patients using population pharmacokinetic method.
Drug Metab Pharmacokinet
; 19(1): 15-23, 2004 Feb.
Artículo
en Inglés
| MEDLINE | ID: mdl-15499165
17.
Effect of renal impairment on the pharmacokinetics, pharmacodynamics, and safety of empagliflozin, a sodium glucose cotransporter 2 inhibitor, in Japanese patients with type 2 diabetes mellitus.
Clin Ther
; 36(11): 1606-15, 2014 Nov 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-25199997
18.
Pharmacokinetics, pharmacodynamics, safety and tolerability of 4 weeks' treatment with empagliflozin in Japanese patients with type 2 diabetes mellitus.
J Diabetes Investig
; 4(6): 613-7, 2013 Nov 27.
Artículo
en Inglés
| MEDLINE | ID: mdl-24843716
19.
Safety, tolerability, pharmacokinetics and pharmacodynamics of single doses of empagliflozin, a sodium glucose cotransporter 2 (SGLT2) inhibitor, in healthy Japanese subjects.
Drug Metab Pharmacokinet
; 28(3): 213-9, 2013.
Artículo
en Inglés
| MEDLINE | ID: mdl-23149871
20.
Efficacy and safety of extended- versus immediate-release pramipexole in Japanese patients with advanced and L-dopa-undertreated Parkinson disease: a double-blind, randomized trial.
Clin Neuropharmacol
; 35(4): 174-81, 2012.
Artículo
en Inglés
| MEDLINE | ID: mdl-22801294