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1.
Practical QSP application from the preclinical phase to enhance the probability of clinical success: Insights from case studies in oncology.
Drug Metab Pharmacokinet
; 56: 101020, 2024 May 09.
Artículo
en Inglés
| MEDLINE | ID: mdl-38797089
2.
Application of hybrid approach based on empirical and physiological concept for predicting pharmacokinetics in humans--usefulness of exponent on prospective evaluation of predictability.
Drug Metab Dispos
; 41(2): 498-507, 2013 Feb.
Artículo
en Inglés
| MEDLINE | ID: mdl-23209193
3.
Virtual clinical trial simulations for a novel KRASG12C inhibitor (ASP2453) in non-small cell lung cancer.
CPT Pharmacometrics Syst Pharmacol
; 10(8): 864-877, 2021 08.
Artículo
en Inglés
| MEDLINE | ID: mdl-34043291
4.
Quantitative Systems Pharmacology Approaches for Immuno-Oncology: Adding Virtual Patients to the Development Paradigm.
Clin Pharmacol Ther
; 109(3): 605-618, 2021 03.
Artículo
en Inglés
| MEDLINE | ID: mdl-32686076
5.
[An introduction to QSP modeling for pharmacologists].
Nihon Yakurigaku Zasshi
; 154(3): 143-150, 2019.
Artículo
en Japonés
| MEDLINE | ID: mdl-31527365
6.
Effects of Adjuvant-Induced Inflammation on Disposition of Diclofenac and Its Metabolites in Perfused Rat Liver.
J Pharm Sci
; 106(4): 1175-1182, 2017 04.
Artículo
en Inglés
| MEDLINE | ID: mdl-28062205
7.
Application of a physiologically based pharmacokinetic model informed by a top-down approach for the prediction of pharmacokinetics in chronic kidney disease patients.
AAPS J
; 16(5): 1018-28, 2014 Sep.
Artículo
en Inglés
| MEDLINE | ID: mdl-24912798
8.
A Quantitative Systems Pharmacology Consortium Approach to Managing Immunogenicity of Therapeutic Proteins.
CPT Pharmacometrics Syst Pharmacol
; 8(11): 773-776, 2019 11.
Artículo
en Inglés
| MEDLINE | ID: mdl-31529677
9.
Development of a hybrid physiologically based pharmacokinetic model with drug-specific scaling factors in rat to improve prediction of human pharmacokinetics.
J Pharm Sci
; 102(11): 4193-204, 2013 Nov.
Artículo
en Inglés
| MEDLINE | ID: mdl-24018828
10.
Translational research in drug discovery - current issues and perspectives.
Nihon Yakurigaku Zasshi
; 148(6): 296-301, 2016.
Artículo
en Japonés
| MEDLINE | ID: mdl-27904007
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