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1.
Treating gout with pegloticase, a PEGylated urate oxidase, provides insight into the importance of uric acid as an antioxidant in vivo.
Proc Natl Acad Sci U S A
; 107(32): 14351-6, 2010 Aug 10.
Artículo
en Inglés
| MEDLINE | ID: mdl-20660758
2.
Induced and pre-existing anti-polyethylene glycol antibody in a trial of every 3-week dosing of pegloticase for refractory gout, including in organ transplant recipients.
Arthritis Res Ther
; 16(2): R63, 2014 Mar 07.
Artículo
en Inglés
| MEDLINE | ID: mdl-24602182
3.
Pharmacokinetics and pharmacodynamics of intravenous PEGylated recombinant mammalian urate oxidase in patients with refractory gout.
Arthritis Rheum
; 56(3): 1021-8, 2007 Mar.
Artículo
en Inglés
| MEDLINE | ID: mdl-17328081
4.
Control of hyperuricemia in subjects with refractory gout, and induction of antibody against poly(ethylene glycol) (PEG), in a phase I trial of subcutaneous PEGylated urate oxidase.
Arthritis Res Ther
; 8(1): R12, 2006.
Artículo
en Inglés
| MEDLINE | ID: mdl-16356199
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