Detalles de la búsqueda
1.
Toxicokinetics of U-47700, tramadol, and their main metabolites in pigs following intravenous administration: is a multiple species allometric scaling approach useful for the extrapolation of toxicokinetic parameters to humans?
Arch Toxicol
; 95(12): 3681-3693, 2021 Dec.
Artículo
en Inglés
| MEDLINE | ID: mdl-34604914
2.
Is adipose tissue suitable for detection of (synthetic) cannabinoids? A comparative study analyzing antemortem and postmortem specimens following pulmonary administration of JWH-210, RCS-4, as well as ∆9-tetrahydrocannabinol to pigs.
Arch Toxicol
; 94(10): 3421-3431, 2020 10.
Artículo
en Inglés
| MEDLINE | ID: mdl-32666126
3.
Time- and temperature-dependent postmortem concentration changes of the (synthetic) cannabinoids JWH-210, RCS-4, as well as ∆9-tetrahydrocannabinol following pulmonary administration to pigs.
Arch Toxicol
; 94(5): 1585-1599, 2020 05.
Artículo
en Inglés
| MEDLINE | ID: mdl-32189036
4.
Distribution of the (synthetic) cannabinoids JWH-210, RCS-4, as well as ∆9-tetrahydrocannabinol following pulmonary administration to pigs.
Arch Toxicol
; 93(8): 2211-2218, 2019 08.
Artículo
en Inglés
| MEDLINE | ID: mdl-31227841
5.
The feasibility of physiologically based pharmacokinetic modeling in forensic medicine illustrated by the example of morphine.
Int J Legal Med
; 132(2): 415-424, 2018 Mar.
Artículo
en Inglés
| MEDLINE | ID: mdl-29196879
6.
The role of SDF-1 in homing of human adipose-derived stem cells.
Wound Repair Regen
; 23(1): 82-9, 2015.
Artículo
en Inglés
| MEDLINE | ID: mdl-25581571
7.
Simultaneous LC-MS/MS determination of JWH-210, RCS-4, ∆(9)-tetrahydrocannabinol, and their main metabolites in pig and human serum, whole blood, and urine for comparing pharmacokinetic data.
Anal Bioanal Chem
; 407(13): 3775-86, 2015 May.
Artículo
en Inglés
| MEDLINE | ID: mdl-25772567
8.
Can JWH-210 and JWH-122 be detected in adipose tissue four weeks after single oral drug administration to rats?
Biomed Chromatogr
; 28(8): 1043-7, 2014 Aug.
Artículo
en Inglés
| MEDLINE | ID: mdl-24474420
9.
Development and validation of two LC-MS/MS methods for the detection and quantification of amphetamines, designer amphetamines, benzoylecgonine, benzodiazepines, opiates, and opioids in urine using turbulent flow chromatography.
Anal Bioanal Chem
; 405(1): 247-58, 2013 Jan.
Artículo
en Inglés
| MEDLINE | ID: mdl-23076398
10.
'Flying high?'-Jump from a height in a 'Spice' high?: A case report on the synthetic cannabinoid 5F-MDMB-P7AICA.
Drug Test Anal
; 15(3): 368-373, 2023 Mar.
Artículo
en Inglés
| MEDLINE | ID: mdl-36415074
11.
Are the (New) Synthetic Opioids U-47700, Tramadol and Their Main Metabolites Prone to Time-Dependent Postmortem Redistribution?-A Systematic Study Using an In Vivo Pig Model.
J Anal Toxicol
; 47(3): 236-244, 2023 Mar 24.
Artículo
en Inglés
| MEDLINE | ID: mdl-36242582
12.
Are the N-demethylated metabolites of U-47700 more active than their parent compound? In vitro µ-opioid receptor activation of N-desmethyl-U-47700 and N,N-bisdesmethyl-U-47700.
Drug Test Anal
; 14(4): 713-717, 2022 Apr.
Artículo
en Inglés
| MEDLINE | ID: mdl-34669261
13.
Systematic Studies on Temperature-Dependent In Vitro Stability during Storage and Smoking of the Synthetic Cannabinoid 5F-MDMB-P7AICA.
J Anal Toxicol
; 46(4): 374-382, 2022 Apr 21.
Artículo
en Inglés
| MEDLINE | ID: mdl-33629711
14.
Perimortem Distribution of U-47700, Tramadol and Their Main Metabolites in Pigs Following Intravenous Administration.
J Anal Toxicol
; 46(5): 479-486, 2022 May 20.
Artículo
en Inglés
| MEDLINE | ID: mdl-33950247
15.
Can a Recently Developed Pig Model Be Used for In Vivo Metabolism Studies of 7-Azaindole-Derived Synthetic Cannabinoids? A Study Using 5F-MDMB-P7AICA.
J Anal Toxicol
; 45(6): 593-604, 2021 Jul 10.
Artículo
en Inglés
| MEDLINE | ID: mdl-32886783
16.
Comparison of in vitro and in vivo models for the elucidation of metabolic patterns of 7-azaindole-derived synthetic cannabinoids exemplified using cumyl-5F-P7AICA.
Drug Test Anal
; 13(1): 74-90, 2021 Jan.
Artículo
en Inglés
| MEDLINE | ID: mdl-32678962
17.
Are pigs a suitable animal model for in vivo metabolism studies of new psychoactive substances? A comparison study using different in vitro/in vivo tools and U-47700 as model drug.
Toxicol Lett
; 329: 12-19, 2020 Sep 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-32380122
18.
Studies on the in vitro and in vivo metabolism of the synthetic opioids U-51754, U-47931E, and methoxyacetylfentanyl using hyphenated high-resolution mass spectrometry.
Sci Rep
; 9(1): 13774, 2019 09 24.
Artículo
en Inglés
| MEDLINE | ID: mdl-31551531
19.
Development of an In-vitro Drug Delivery Efficiency Test for a Pulmonary Toxicokinetic Pig Study.
Curr Drug Deliv
; 15(8): 1167-1171, 2018.
Artículo
en Inglés
| MEDLINE | ID: mdl-29446742
20.
Can toxicokinetics of (synthetic) cannabinoids in pigs after pulmonary administration be upscaled to humans by allometric techniques?
Biochem Pharmacol
; 155: 403-418, 2018 09.
Artículo
en Inglés
| MEDLINE | ID: mdl-30048626