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1.
Quantification of antiangiogenic treatment effects on tissue heterogeneity in glioma tumour xenograft model using a combination of DCE-MRI and 3D-ultramicroscopy.
Eur Radiol
; 27(7): 2894-2902, 2017 Jul.
Artículo
en Inglés
| MEDLINE | ID: mdl-27830379
2.
A novel glycoengineered bispecific antibody format for targeted inhibition of epidermal growth factor receptor (EGFR) and insulin-like growth factor receptor type I (IGF-1R) demonstrating unique molecular properties.
J Biol Chem
; 289(27): 18693-706, 2014 Jul 04.
Artículo
en Inglés
| MEDLINE | ID: mdl-24841203
3.
Immunoglobulin domain crossover as a generic approach for the production of bispecific IgG antibodies.
Proc Natl Acad Sci U S A
; 108(27): 11187-92, 2011 Jul 05.
Artículo
en Inglés
| MEDLINE | ID: mdl-21690412
4.
Bispecific digoxigenin-binding antibodies for targeted payload delivery.
Proc Natl Acad Sci U S A
; 108(20): 8194-9, 2011 May 17.
Artículo
en Inglés
| MEDLINE | ID: mdl-21536919
5.
Development of tetravalent IgG1 dual targeting IGF-1R-EGFR antibodies with potent tumor inhibition.
Arch Biochem Biophys
; 526(2): 206-18, 2012 Oct 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-22464987
6.
Comparison of the Accuracy of FMT/CT and PET/MRI for the Assessment of Antibody Biodistribution in Squamous Cell Carcinoma Xenografts.
J Nucl Med
; 59(1): 44-50, 2018 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-28848038
7.
Improved decision making for prioritizing tumor targeting antibodies in human xenografts: Utility of fluorescence imaging to verify tumor target expression, antibody binding and optimization of dosage and application schedule.
MAbs
; 9(1): 140-153, 2017 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-27661454
8.
Noninvasive Bioluminescence Imaging of AKT Kinase Activity in Subcutaneous and Orthotopic NSCLC Xenografts: Correlation of AKT Activity with Tumor Growth Kinetics.
Neoplasia
; 19(4): 310-320, 2017 04.
Artículo
en Inglés
| MEDLINE | ID: mdl-28285180
9.
Combination treatment with erlotinib and pertuzumab against human tumor xenografts is superior to monotherapy.
Clin Cancer Res
; 11(14): 5300-9, 2005 Jul 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-16033849
10.
TetraMabs: simultaneous targeting of four oncogenic receptor tyrosine kinases for tumor growth inhibition in heterogeneous tumor cell populations.
Protein Eng Des Sel
; 29(10): 467-475, 2016 10.
Artículo
en Inglés
| MEDLINE | ID: mdl-27578890
11.
Anti-tumoral, anti-angiogenic and anti-metastatic efficacy of a tetravalent bispecific antibody (TAvi6) targeting VEGF-A and angiopoietin-2.
MAbs
; 8(3): 562-73, 2016.
Artículo
en Inglés
| MEDLINE | ID: mdl-26864324
12.
RG7386, a Novel Tetravalent FAP-DR5 Antibody, Effectively Triggers FAP-Dependent, Avidity-Driven DR5 Hyperclustering and Tumor Cell Apoptosis.
Mol Cancer Ther
; 15(5): 946-57, 2016 05.
Artículo
en Inglés
| MEDLINE | ID: mdl-27037412
13.
Interferon Gamma Counteracts the Angiogenic Switch and Induces Vascular Permeability in Dextran Sulfate Sodium Colitis in Mice.
Inflamm Bowel Dis
; 21(10): 2360-71, 2015 Oct.
Artículo
en Inglés
| MEDLINE | ID: mdl-26164664
14.
Quantification of human Alu sequences by real-time PCR--an improved method to measure therapeutic efficacy of anti-metastatic drugs in human xenotransplants.
Clin Exp Metastasis
; 19(7): 571-82, 2002.
Artículo
en Inglés
| MEDLINE | ID: mdl-12498386
15.
Activation of cytosolic phospholipase A2 in human T-lymphocytes involves inhibitor-kappaB and mitogen-activated protein kinases.
Eur J Pharmacol
; 466(1-2): 169-80, 2003 Apr 11.
Artículo
en Inglés
| MEDLINE | ID: mdl-12679154
16.
Comparative analysis of docking motifs in MAP-kinases and nuclear receptors.
J Biomol Struct Dyn
; 20(5): 623-34, 2003 Apr.
Artículo
en Inglés
| MEDLINE | ID: mdl-12643765
17.
Multispectral fluorescence ultramicroscopy: three-dimensional visualization and automatic quantification of tumor morphology, drug penetration, and antiangiogenic treatment response.
Neoplasia
; 16(1): 1-13, 2014 Jan.
Artículo
en Inglés
| MEDLINE | ID: mdl-24563615
18.
Noninvasive measurement of pharmacokinetics by near-infrared fluorescence imaging in the eye of mice.
J Biomed Opt
; 19(1): 16022, 2014 Jan.
Artículo
en Inglés
| MEDLINE | ID: mdl-24474508
19.
Apoptosis imaging for monitoring DR5 antibody accumulation and pharmacodynamics in brain tumors noninvasively.
Cancer Res
; 74(7): 1913-23, 2014 Apr 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-24509903
20.
Dynamic contrast-enhanced micro-computed tomography correlates with 3-dimensional fluorescence ultramicroscopy in antiangiogenic therapy of breast cancer xenografts.
Invest Radiol
; 49(7): 445-56, 2014 Jul.
Artículo
en Inglés
| MEDLINE | ID: mdl-24598441