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1.
Proteogenomic profiling uncovers differential therapeutic vulnerabilities between TCF3::PBX1 and TCF3::HLF translocated B-cell acute lymphoblastic leukemia.
Haematologica
; 2024 Feb 29.
Artículo
en Inglés
| MEDLINE | ID: mdl-38426288
2.
Preferential HDAC6 inhibitors derived from HPOB exhibit synergistic antileukemia activity in combination with decitabine.
Eur J Med Chem
; 272: 116447, 2024 Jun 05.
Artículo
en Inglés
| MEDLINE | ID: mdl-38714044
3.
Co-targeting HSP90 alpha and CDK7 overcomes resistance against HSP90 inhibitors in BCR-ABL1+ leukemia cells.
Cell Death Dis
; 14(12): 799, 2023 12 06.
Artículo
en Inglés
| MEDLINE | ID: mdl-38057328
4.
Synthesis, Antiplasmodial, and Antileukemia Activity of Dihydroartemisinin-HDAC Inhibitor Hybrids as Multitarget Drugs.
Pharmaceuticals (Basel)
; 15(3)2022 Mar 09.
Artículo
en Inglés
| MEDLINE | ID: mdl-35337131
5.
Solid-Phase Synthesis of Cereblon-Recruiting Selective Histone Deacetylase 6 Degraders (HDAC6 PROTACs) with Antileukemic Activity.
J Med Chem
; 65(24): 16860-16878, 2022 12 22.
Artículo
en Inglés
| MEDLINE | ID: mdl-36473103
6.
Development of Fluorinated Peptoid-Based Histone Deacetylase (HDAC) Inhibitors for Therapy-Resistant Acute Leukemia.
J Med Chem
; 65(22): 15457-15472, 2022 11 24.
Artículo
en Inglés
| MEDLINE | ID: mdl-36351184
7.
The Mycotoxin Beauvericin Exhibits Immunostimulatory Effects on Dendritic Cells via Activating the TLR4 Signaling Pathway.
Front Immunol
; 13: 856230, 2022.
Artículo
en Inglés
| MEDLINE | ID: mdl-35464417
8.
The mycotoxin viriditoxin induces leukemia- and lymphoma-specific apoptosis by targeting mitochondrial metabolism.
Cell Death Dis
; 13(11): 938, 2022 11 08.
Artículo
en Inglés
| MEDLINE | ID: mdl-36347842
9.
Development of a First-in-Class Small-Molecule Inhibitor of the C-Terminal Hsp90 Dimerization.
ACS Cent Sci
; 8(5): 636-655, 2022 May 25.
Artículo
en Inglés
| MEDLINE | ID: mdl-35647282
10.
Synergistic induction of apoptosis in resistant head and neck carcinoma and leukemia by alkoxyamide-based histone deacetylase inhibitors.
Eur J Med Chem
; 211: 113095, 2021 Feb 05.
Artículo
en Inglés
| MEDLINE | ID: mdl-33360560
11.
Borinostats: solid-phase synthesis of carborane-capped histone deacetylase inhibitors with a tailor-made selectivity profile.
Chem Sci
; 12(35): 11873-11881, 2021 Sep 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-34659728
12.
Oxa Analogues of Nexturastatâ A Demonstrate Improved HDAC6 Selectivity and Superior Antileukaemia Activity.
ChemMedChem
; 16(11): 1798-1803, 2021 06 07.
Artículo
en Inglés
| MEDLINE | ID: mdl-33629513
13.
4-Acyl Pyrrole Capped HDAC Inhibitors: A New Scaffold for Hybrid Inhibitors of BET Proteins and Histone Deacetylases as Antileukemia Drug Leads.
J Med Chem
; 64(19): 14620-14646, 2021 10 14.
Artículo
en Inglés
| MEDLINE | ID: mdl-34582215
14.
Multicomponent Synthesis, Binding Mode, and Structure-Activity Relationship of Selective Histone Deacetylase 6 (HDAC6) Inhibitors with Bifurcated Capping Groups.
J Med Chem
; 63(18): 10339-10351, 2020 09 24.
Artículo
en Inglés
| MEDLINE | ID: mdl-32803970
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