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1.
LRRK2 protein levels are determined by kinase function and are crucial for kidney and lung homeostasis in mice.
Hum Mol Genet
; 20(21): 4209-23, 2011 Nov 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-21828077
2.
mTOR inhibitor RAD001 (everolimus) has antiangiogenic/vascular properties distinct from a VEGFR tyrosine kinase inhibitor.
Clin Cancer Res
; 15(5): 1612-22, 2009 Mar 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-19223496
3.
Novel 2,7-dialkyl-substituted 5(S)-amino-4(S)-hydroxy-8-phenyl-octanecarboxamide transition state peptidomimetics are potent and orally active inhibitors of human renin.
J Med Chem
; 50(20): 4818-31, 2007 Oct 04.
Artículo
en Inglés
| MEDLINE | ID: mdl-17824679
4.
Structural modification of the P2' position of 2,7-dialkyl-substituted 5(S)-amino-4(S)-hydroxy-8-phenyl-octanecarboxamides: the discovery of aliskiren, a potent nonpeptide human renin inhibitor active after once daily dosing in marmosets.
J Med Chem
; 50(20): 4832-44, 2007 Oct 04.
Artículo
en Inglés
| MEDLINE | ID: mdl-17824680
5.
Behavioral and physiological effects of an infant-neglect manipulation in a bi-parental, twinning primate: impact is dependent on familial factors.
Psychoneuroendocrinology
; 32(4): 331-49, 2007 May.
Artículo
en Inglés
| MEDLINE | ID: mdl-17363175
6.
Aliskiren, a novel, orally effective renin inhibitor, lowers blood pressure in marmosets and spontaneously hypertensive rats.
J Hypertens
; 23(2): 417-26, 2005 Feb.
Artículo
en Inglés
| MEDLINE | ID: mdl-15662231
7.
Deprivation of parenting disrupts development of homeostatic and reward systems in marmoset monkey offspring.
Biol Psychiatry
; 56(2): 72-9, 2004 Jul 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-15231438
8.
Anthranilic acid amides: a novel class of antiangiogenic VEGF receptor kinase inhibitors.
J Med Chem
; 45(26): 5687-93, 2002 Dec 19.
Artículo
en Inglés
| MEDLINE | ID: mdl-12477352
9.
Behavioral and cardiophysiological responses of common marmosets (Callithrix jacchus) to confrontations with opposite-sexed strangers.
Primates
; 45(3): 187-96, 2004 Jul.
Artículo
en Inglés
| MEDLINE | ID: mdl-15179557
10.
Behavioral and cardiophysiological responses of common marmosets (Callithrix jacchus) to social and environmental changes.
Primates
; 43(3): 201-16, 2002 Jul.
Artículo
en Inglés
| MEDLINE | ID: mdl-12145401
11.
Effects of the dual phosphatidylinositol 3-kinase/mammalian target of rapamycin inhibitor NVP-BEZ235 on the tumor vasculature: implications for clinical imaging.
Cancer Res
; 68(16): 6598-607, 2008 Aug 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-18701483
12.
Autonomic arousal in an appetitive context in primates: a behavioural and neural analysis.
Eur J Neurosci
; 21(6): 1733-40, 2005 Mar.
Artículo
en Inglés
| MEDLINE | ID: mdl-15845101
13.
Structure-based design of aliskiren, a novel orally effective renin inhibitor.
Biochem Biophys Res Commun
; 308(4): 698-705, 2003 Sep 05.
Artículo
en Inglés
| MEDLINE | ID: mdl-12927775
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