Detalles de la búsqueda
1.
SAR inspired by aldehyde oxidase (AO) metabolism: Discovery of novel, CNS penetrant tricyclic M4 PAMs.
Bioorg Med Chem Lett
; 29(16): 2224-2228, 2019 08 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-31248774
2.
Detection of pleiotropy through a Phenome-wide association study (PheWAS) of epidemiologic data as part of the Environmental Architecture for Genes Linked to Environment (EAGLE) study.
PLoS Genet
; 10(12): e1004678, 2014 Dec.
Artículo
en Inglés
| MEDLINE | ID: mdl-25474351
3.
Detection of copy number variation by SNP-allelotyping.
J Neurogenet
; 29(1): 4-7, 2015 Mar.
Artículo
en Inglés
| MEDLINE | ID: mdl-24830919
4.
Lipid trait-associated genetic variation is associated with gallstone disease in the diverse Third National Health and Nutrition Examination Survey (NHANES III).
BMC Med Genet
; 14: 120, 2013 Nov 21.
Artículo
en Inglés
| MEDLINE | ID: mdl-24256507
5.
Effects of smoking on the genetic risk of obesity: the population architecture using genomics and epidemiology study.
BMC Med Genet
; 14: 6, 2013 Jan 11.
Artículo
en Inglés
| MEDLINE | ID: mdl-23311614
6.
Identification and confirmation of an exonic splicing enhancer variation in exon 5 of the Alzheimer disease associated PICALM gene.
Ann Hum Genet
; 76(6): 448-53, 2012 Nov.
Artículo
en Inglés
| MEDLINE | ID: mdl-22943764
7.
Serum vitamins A and E as modifiers of lipid trait genetics in the National Health and Nutrition Examination Surveys as part of the Population Architecture using Genomics and Epidemiology (PAGE) study.
Hum Genet
; 131(11): 1699-708, 2012 Nov.
Artículo
en Inglés
| MEDLINE | ID: mdl-22688886
8.
Development of VU6019650: A Potent, Highly Selective, and Systemically Active Orthosteric Antagonist of the M5 Muscarinic Acetylcholine Receptor for the Treatment of Opioid Use Disorder.
J Med Chem
; 65(8): 6273-6286, 2022 04 28.
Artículo
en Inglés
| MEDLINE | ID: mdl-35417155
9.
Inherited human cPLA(2alpha) deficiency is associated with impaired eicosanoid biosynthesis, small intestinal ulceration, and platelet dysfunction.
J Clin Invest
; 118(6): 2121-31, 2008 Jun.
Artículo
en Inglés
| MEDLINE | ID: mdl-18451993
10.
C3 R102G polymorphism increases risk of age-related macular degeneration.
Hum Mol Genet
; 17(12): 1821-4, 2008 Jun 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-18325906
11.
Genomic convergence to identify candidate genes for Alzheimer disease on chromosome 10.
Hum Mutat
; 30(3): 463-71, 2009 Mar.
Artículo
en Inglés
| MEDLINE | ID: mdl-19241460
12.
CALHM1 polymorphism is not associated with late-onset Alzheimer disease.
Ann Hum Genet
; 73(Pt 3): 379-81, 2009 May.
Artículo
en Inglés
| MEDLINE | ID: mdl-19472444
13.
The enteropathy of prostaglandin deficiency.
J Gastroenterol
; 44 Suppl 19: 1-7, 2009.
Artículo
en Inglés
| MEDLINE | ID: mdl-19148786
14.
3'-Intercalation of a N2-dG 1R-trans-anti-benzo[c]phenanthrene DNA adduct in an iterated (CG)3 repeat.
Chem Res Toxicol
; 21(7): 1348-58, 2008 Jul.
Artículo
en Inglés
| MEDLINE | ID: mdl-18549249
15.
Effect of heterogeneity on the chromosome 10 risk in late-onset Alzheimer disease.
Hum Mutat
; 28(11): 1065-73, 2007 Nov.
Artículo
en Inglés
| MEDLINE | ID: mdl-17573676
16.
SNPs in Multi-species Conserved Sequences (MCS) as useful markers in association studies: a practical approach.
BMC Genomics
; 8: 266, 2007 Aug 06.
Artículo
en Inglés
| MEDLINE | ID: mdl-17683615
17.
Haplotypes spanning the complement factor H gene are protective against age-related macular degeneration.
Invest Ophthalmol Vis Sci
; 48(9): 4277-83, 2007 Sep.
Artículo
en Inglés
| MEDLINE | ID: mdl-17724217
18.
Independent effects of complement factor H Y402H polymorphism and cigarette smoking on risk of age-related macular degeneration.
Ophthalmology
; 114(6): 1151-6, 2007 Jun.
Artículo
en Inglés
| MEDLINE | ID: mdl-17241667
19.
Functional candidate genes in age-related macular degeneration: significant association with VEGF, VLDLR, and LRP6.
Invest Ophthalmol Vis Sci
; 47(1): 329-35, 2006 Jan.
Artículo
en Inglés
| MEDLINE | ID: mdl-16384981
20.
Rare variant APOC3 R19X is associated with cardio-protective profiles in a diverse population-based survey as part of the Epidemiologic Architecture for Genes Linked to Environment Study.
Circ Cardiovasc Genet
; 7(6): 848-53, 2014 Dec.
Artículo
en Inglés
| MEDLINE | ID: mdl-25363704