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1.
Crowdsourced benchmarking of taxonomic metagenome profilers: lessons learned from the sbv IMPROVER Microbiomics challenge.
BMC Genomics
; 23(1): 624, 2022 Aug 30.
Artículo
en Inglés
| MEDLINE | ID: mdl-36042406
2.
Both K63 and K48 ubiquitin linkages signal lysosomal degradation of the LDL receptor.
J Lipid Res
; 54(5): 1410-20, 2013 May.
Artículo
en Inglés
| MEDLINE | ID: mdl-23419260
3.
LDL Receptor Pathway Regulation by miR-224 and miR-520d.
Front Cardiovasc Med
; 7: 81, 2020.
Artículo
en Inglés
| MEDLINE | ID: mdl-32528976
4.
CDK8 Regulates Insulin Secretion and Mediates Postnatal and Stress-Induced Expression of Neuropeptides in Pancreatic ß Cells.
Cell Rep
; 28(11): 2892-2904.e7, 2019 Sep 10.
Artículo
en Inglés
| MEDLINE | ID: mdl-31509750
5.
Bile acids and gene regulation: from nuclear receptors to chromatin.
Front Biosci
; 13: 6276-88, 2008 May 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-18508660
6.
The pharmacological exploitation of cholesterol 7alpha-hydroxylase, the key enzyme in bile acid synthesis: from binding resins to chromatin remodelling to reduce plasma cholesterol.
Pharmacol Ther
; 116(3): 449-72, 2007 Dec.
Artículo
en Inglés
| MEDLINE | ID: mdl-17959250
7.
Interrogating the microbiome: experimental and computational considerations in support of study reproducibility.
Drug Discov Today
; 23(9): 1644-1657, 2018 09.
Artículo
en Inglés
| MEDLINE | ID: mdl-29890228
8.
The biological effects of long-term exposure of human bronchial epithelial cells to total particulate matter from a candidate modified-risk tobacco product.
Toxicol In Vitro
; 50: 95-108, 2018 Aug.
Artículo
en Inglés
| MEDLINE | ID: mdl-29524472
9.
Assessment of the impact of aerosol from a potential modified risk tobacco product compared with cigarette smoke on human organotypic oral epithelial cultures under different exposure regimens.
Food Chem Toxicol
; 115: 148-169, 2018 May.
Artículo
en Inglés
| MEDLINE | ID: mdl-29505817
10.
Comparative systems toxicology analysis of cigarette smoke and aerosol from a candidate modified risk tobacco product in organotypic human gingival epithelial cultures: A 3-day repeated exposure study.
Food Chem Toxicol
; 101: 15-35, 2017 Mar.
Artículo
en Inglés
| MEDLINE | ID: mdl-28025120
11.
Chlamydia pneumoniae acute liver infection affects hepatic cholesterol and triglyceride metabolism in mice.
Atherosclerosis
; 241(2): 471-9, 2015 Aug.
Artículo
en Inglés
| MEDLINE | ID: mdl-26086356
12.
The LXR-Idol axis differentially regulates plasma LDL levels in primates and mice.
Cell Metab
; 20(5): 910-918, 2014 Nov 04.
Artículo
en Inglés
| MEDLINE | ID: mdl-25440061
13.
Corrigendum to "The biological effects of long-term exposure of human bronchial epithelial cells to total particulate matter from a candidate modified-risk tobacco product" published in Toxicology in Vitro, Volume 50, August 2018, Pages 95-108.
Toxicol In Vitro
; 56: 194-195, 2019 04.
Artículo
en Inglés
| MEDLINE | ID: mdl-30686568
14.
Site-directed mutagenesis to study the role of specific amino acids in the ligand binding domain of PPARs.
Methods Mol Biol
; 952: 137-44, 2013.
Artículo
en Inglés
| MEDLINE | ID: mdl-23100229
15.
IDOL stimulates clathrin-independent endocytosis and multivesicular body-mediated lysosomal degradation of the low-density lipoprotein receptor.
Mol Cell Biol
; 33(8): 1503-14, 2013 Apr.
Artículo
en Inglés
| MEDLINE | ID: mdl-23382078
16.
Targeted disruption of the idol gene alters cellular regulation of the low-density lipoprotein receptor by sterols and liver x receptor agonists.
Mol Cell Biol
; 31(9): 1885-93, 2011 May.
Artículo
en Inglés
| MEDLINE | ID: mdl-21343340
17.
Structural insight into peroxisome proliferator-activated receptor gamma binding of two ureidofibrate-like enantiomers by molecular dynamics, cofactor interaction analysis, and site-directed mutagenesis.
J Med Chem
; 53(11): 4354-66, 2010 Jun 10.
Artículo
en Inglés
| MEDLINE | ID: mdl-20462215
18.
Crystal structure of the peroxisome proliferator-activated receptor gamma (PPARgamma) ligand binding domain complexed with a novel partial agonist: a new region of the hydrophobic pocket could be exploited for drug design.
J Med Chem
; 51(24): 7768-76, 2008 Dec 25.
Artículo
en Inglés
| MEDLINE | ID: mdl-19053776
19.
Insights in the regulation of cholesterol 7alpha-hydroxylase gene reveal a target for modulating bile acid synthesis.
Hepatology
; 46(3): 885-97, 2007 Sep.
Artículo
en Inglés
| MEDLINE | ID: mdl-17654698
20.
Peroxisome proliferator-activated receptor gamma dances with different partners in macrophage and adipocytes.
Mol Cell Biol
; 30(9): 2076-7, 2010 May.
Artículo
en Inglés
| MEDLINE | ID: mdl-20176804
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