Detalles de la búsqueda
1.
Pharmacokinetics and safety of indacaterol and glycopyrronium (IND/GLY) following repeated once daily inhalation from a fixed-dose combination in healthy Chinese subjectsâ©.
Int J Clin Pharmacol Ther
; 55(2): 147-155, 2017 Feb.
Artículo
en Inglés
| MEDLINE | ID: mdl-27841152
2.
Population pharmacokinetics of IND/GLY (indacaterol/glycopyrronium) in COPD patients.
Int J Clin Pharmacol Ther
; 54(6): 405-15, 2016 Jun.
Artículo
en Inglés
| MEDLINE | ID: mdl-27049057
3.
Effect of dual bronchodilation with QVA149 on cardiac safety in healthy volunteers.
Int J Clin Pharmacol Ther
; 52(5): 369-80, 2014 May.
Artículo
en Inglés
| MEDLINE | ID: mdl-24569129
4.
Glycopyrronium does not affect QT interval in healthy subjects: a randomized, three- period, cross-over, placebo- and positive-controlled study.
Int J Clin Pharmacol Ther
; 52(9): 739-45, 2014 Sep.
Artículo
en Inglés
| MEDLINE | ID: mdl-24986094
5.
Midostaurin drug interaction profile: a comprehensive assessment of CYP3A, CYP2B6, and CYP2C8 drug substrates, and oral contraceptives in healthy participants.
Cancer Chemother Pharmacol
; 93(5): 439-453, 2024 May.
Artículo
en Inglés
| MEDLINE | ID: mdl-38270613
6.
Determination of the pharmacokinetics of glycopyrronium in the lung using a population pharmacokinetic modelling approach.
Br J Clin Pharmacol
; 76(6): 868-79, 2013 Dec.
Artículo
en Inglés
| MEDLINE | ID: mdl-23506208
7.
Effect of cimetidine, a model drug for inhibition of the organic cation transport (OCT2/MATE1) in the kidney, on the pharmacokinetics of glycopyrronium.
Int J Clin Pharmacol Ther
; 51(10): 771-9, 2013 Oct.
Artículo
en Inglés
| MEDLINE | ID: mdl-24040847
8.
Pharmacokinetics of multiple inhaled NVA237 doses in patients with chronic obstructive pulmonary disease (COPD).
Int J Clin Pharmacol Ther
; 50(2): 118-28, 2012 Feb.
Artículo
en Inglés
| MEDLINE | ID: mdl-22257577
9.
Evaluation of drug-drug interactions between midostaurin and strong CYP3A4 inhibitors in patients with FLT-3-mutated acute myeloid leukemia (AML).
Cancer Chemother Pharmacol
; 90(1): 19-27, 2022 07.
Artículo
en Inglés
| MEDLINE | ID: mdl-35751657
10.
Phase II, Randomized Study of Spartalizumab (PDR001), an Anti-PD-1 Antibody, versus Chemotherapy in Patients with Recurrent/Metastatic Nasopharyngeal Cancer.
Clin Cancer Res
; 27(23): 6413-6423, 2021 12 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-34433653
11.
Pharmacokinetics, metabolism, and disposition of deferasirox in beta-thalassemic patients with transfusion-dependent iron overload who are at pharmacokinetic steady state.
Drug Metab Dispos
; 38(5): 808-16, 2010 May.
Artículo
en Inglés
| MEDLINE | ID: mdl-20097723
12.
Early clinical development of artemether-lumefantrine dispersible tablet: palatability of three flavours and bioavailability in healthy subjects.
Malar J
; 9: 253, 2010 Sep 03.
Artículo
en Inglés
| MEDLINE | ID: mdl-20815879
13.
Correction to: Midostaurin drug interaction profile: a comprehensive assessment of CYP3A, CYP2B6, and CYP2C8 drug substrates, and oral contraceptives in healthy participants.
Cancer Chemother Pharmacol
; 2024 Mar 05.
Artículo
en Inglés
| MEDLINE | ID: mdl-38438807
14.
Absolute oral bioavailability and disposition of deferasirox in healthy human subjects.
J Clin Pharmacol
; 48(8): 919-25, 2008 Aug.
Artículo
en Inglés
| MEDLINE | ID: mdl-18508948
15.
Effect of food, type of food, and time of food intake on deferasirox bioavailability: recommendations for an optimal deferasirox administration regimen.
J Clin Pharmacol
; 48(4): 428-35, 2008 Apr.
Artículo
en Inglés
| MEDLINE | ID: mdl-18281442
16.
Randomized phase II trial of deferasirox (Exjade, ICL670), a once-daily, orally-administered iron chelator, in comparison to deferoxamine in thalassemia patients with transfusional iron overload.
Haematologica
; 91(7): 873-80, 2006 Jul.
Artículo
en Inglés
| MEDLINE | ID: mdl-16818273
17.
Phase II clinical evaluation of deferasirox, a once-daily oral chelating agent, in pediatric patients with beta-thalassemia major.
Haematologica
; 91(10): 1343-51, 2006 Oct.
Artículo
en Inglés
| MEDLINE | ID: mdl-17018383
18.
Pharmacokinetics of Glycopyrronium Following Repeated Once-Daily Inhalation in Healthy Chinese Subjects.
Eur J Drug Metab Pharmacokinet
; 41(6): 723-731, 2016 Dec.
Artículo
en Inglés
| MEDLINE | ID: mdl-26428357
19.
Safety, tolerability, and pharmacokinetics of ICL670, a new orally active iron-chelating agent in patients with transfusion-dependent iron overload due to beta-thalassemia.
J Clin Pharmacol
; 43(6): 565-72, 2003 Jun.
Artículo
en Inglés
| MEDLINE | ID: mdl-12817519
20.
Pharmacokinetics and variability of mycophenolic acid from enteric-coated mycophenolate sodium compared with mycophenolate mofetil in de novo heart transplant recipients.
Clin Transplant
; 21(1): 18-23, 2007.
Artículo
en Inglés
| MEDLINE | ID: mdl-17302587