Detalles de la búsqueda
1.
Exploration of antiproliferative potential of modified triazole-benzohydrazone scaffold: Multitarget approach.
Arch Pharm (Weinheim)
; 357(2): e2300383, 2024 Feb.
Artículo
en Inglés
| MEDLINE | ID: mdl-37946599
2.
Nitroimidazole derivatives potentiated against tumor hypoxia: Design, synthesis, antitumor activity, molecular docking study, and QSAR study.
Drug Dev Res
; 85(1): e22126, 2024 Feb.
Artículo
en Inglés
| MEDLINE | ID: mdl-37915124
3.
Insights into modulating the monastrol scaffold: Development of new pyrimidinones as Eg5 inhibitors with anticancer activity.
Arch Pharm (Weinheim)
; 355(10): e2200029, 2022 Oct.
Artículo
en Inglés
| MEDLINE | ID: mdl-35642307
4.
Design, synthesis, and analysis of antiproliferative and apoptosis-inducing activities of nitrile derivatives containing a benzofuran scaffold: EGFR inhibition assay and molecular modelling study.
J Enzyme Inhib Med Chem
; 36(1): 1488-1499, 2021 Dec.
Artículo
en Inglés
| MEDLINE | ID: mdl-34227457
5.
Design, synthesis and molecular modeling of phenyl dihydropyridazinone derivatives as B-Raf inhibitors with anticancer activity.
Bioorg Chem
; 103: 104148, 2020 10.
Artículo
en Inglés
| MEDLINE | ID: mdl-32763518
6.
Design, Synthesis and Anticancer Evaluation of New Substituted Thiophene-Quinoline Derivatives.
Bioorg Med Chem
; 27(19): 115026, 2019 10 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-31416740
7.
Dihydrofolate reductase inhibition effect of 5-substituted pyrido[2,3-d]pyrimidines: Synthesis, antitumor activity and molecular modeling study.
Bioorg Chem
; 90: 103076, 2019 09.
Artículo
en Inglés
| MEDLINE | ID: mdl-31260878
8.
Identification of 1H-pyrazolo[3,4-b]pyridine derivatives as potent ALK-L1196M inhibitors.
J Enzyme Inhib Med Chem
; 34(1): 1426-1438, 2019 Dec.
Artículo
en Inglés
| MEDLINE | ID: mdl-31401883
9.
Design, synthesis, and molecular modeling of heterocyclic bioisostere as potent PDE4 inhibitors.
Arch Pharm (Weinheim)
; 351(3-4): e1700403, 2018 Apr.
Artículo
en Inglés
| MEDLINE | ID: mdl-29573453
10.
Enantioselective ruthenium-catalyzed 1,3-dipolar cycloadditions between C-carboalkoxy ketonitrones and methacrolein: solvent effect on reaction selectivity and its rational.
J Org Chem
; 79(8): 3414-26, 2014 Apr 18.
Artículo
en Inglés
| MEDLINE | ID: mdl-24605848
11.
Modified Tacrine Derivatives as Multitarget-Directed Ligands for the Treatment of Alzheimer's Disease: Synthesis, Biological Evaluation, and Molecular Modeling Study.
ACS Omega
; 8(29): 26012-26034, 2023 Jul 25.
Artículo
en Inglés
| MEDLINE | ID: mdl-37521639
12.
Synthesis, Antitumor Activity, and In Silico Drug Design of New Thieno[2,3-d]Pyrimidine-4-One Derivatives as Nonclassical Lipophilic Dihydrofolate Reductase Inhibitors.
ACS Omega
; 7(49): 45455-45468, 2022 Dec 13.
Artículo
en Inglés
| MEDLINE | ID: mdl-36530275
13.
Chiral N-heterocyclic carbene-copper(I)-catalyzed asymmetric allylic arylation of aliphatic allylic bromides: steric and electronic effects on γ-selectivity.
J Org Chem
; 76(5): 1398-408, 2011 Mar 04.
Artículo
en Inglés
| MEDLINE | ID: mdl-21265531
14.
Correction to "Enantioselective Ruthenium-Catalyzed 1,3-Dipolar Cycloadditions between C-Carboalkoxy Ketonitrones and Methacrolein: Solvent Effect on Reaction Selectivity and Its Rationale".
J Org Chem
; 80(21): 11226, 2015 Nov 06.
Artículo
en Inglés
| MEDLINE | ID: mdl-26505292
15.
1,2,3-Triazole-Chalcone hybrids: Synthesis, in vitro cytotoxic activity and mechanistic investigation of apoptosis induction in multiple myeloma RPMI-8226.
Eur J Med Chem
; 189: 112062, 2020 Mar 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-31986406
16.
Design, synthesis and docking study of novel picolinamide derivatives as anticancer agents and VEGFR-2 inhibitors.
Eur J Med Chem
; 168: 315-329, 2019 Apr 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-30826508
17.
Copper-catalyzed asymmetric allylic substitution with aryl and ethyl Grignard reagents.
Chem Commun (Camb)
; (41): 5140-2, 2008 Nov 07.
Artículo
en Inglés
| MEDLINE | ID: mdl-18956048
18.
Synthesis and anticancer activity of new dihydropyrimidinone derivatives.
Eur J Med Chem
; 156: 304-315, 2018 Aug 05.
Artículo
en Inglés
| MEDLINE | ID: mdl-30015070
19.
Efficient chiral N-heterocyclic carbene/copper(I)-catalyzed asymmetric allylic arylation with aryl Grignard reagents.
Angew Chem Int Ed Engl
; 48(46): 8733-5, 2009.
Artículo
en Inglés
| MEDLINE | ID: mdl-19834927
20.
Invasive mucormycosis in a patient with liver cirrhosis: case report and review of the literature.
Hepat Mon
; 13(8): e10858, 2013.
Artículo
en Inglés
| MEDLINE | ID: mdl-24171007