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1.
Recent insights into the hepatoprotective potential of medicinal plants and plant-derived compounds.
Phytother Res
; 37(5): 2102-2118, 2023 May.
Artículo
en Inglés
| MEDLINE | ID: mdl-37022281
2.
Histone Deacetylase Inhibitors as Multitarget-Directed Epi-Drugs in Blocking PI3K Oncogenic Signaling: A Polypharmacology Approach.
Int J Mol Sci
; 21(21)2020 Nov 02.
Artículo
en Inglés
| MEDLINE | ID: mdl-33147762
3.
Cellular Effects of Butyrate on Vascular Smooth Muscle Cells are Mediated through Disparate Actions on Dual Targets, Histone Deacetylase (HDAC) Activity and PI3K/Akt Signaling Network.
Int J Mol Sci
; 20(12)2019 Jun 14.
Artículo
en Inglés
| MEDLINE | ID: mdl-31197106
4.
Computer-aided design of negative allosteric modulators of metabotropic glutamate receptor 5 (mGluR5): Comparative molecular field analysis of aryl ether derivatives.
Bioorg Med Chem Lett
; 26(4): 1140-4, 2016 Feb 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-26826734
5.
Amides are excellent mimics of phosphate internucleoside linkages and are well tolerated in short interfering RNAs.
Nucleic Acids Res
; 42(10): 6542-51, 2014 Jun.
Artículo
en Inglés
| MEDLINE | ID: mdl-24813446
6.
Performance evaluation of structure based and ligand based virtual screening methods on ten selected anti-cancer targets.
Bioorg Med Chem Lett
; 25(20): 4632-6, 2015 Oct 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-26330079
7.
Identification of indole-based natural compounds as inhibitors of PARP-1 against triple-negative breast cancer: a computational study.
J Biomol Struct Dyn
; 42(5): 2667-2680, 2024 Mar.
Artículo
en Inglés
| MEDLINE | ID: mdl-37154583
8.
Dual Anti-Inflammatory and Anticancer Activity of Novel 1,5-Diaryl Pyrazole Derivatives: Molecular Modeling, Synthesis, In Vitro Activity, and Dynamics Study.
Biomedicines
; 12(4)2024 Apr 03.
Artículo
en Inglés
| MEDLINE | ID: mdl-38672144
9.
Compounds from diverse natural origin against triple-negative breast cancer: A comprehensive review.
Chem Biol Drug Des
; 101(1): 218-243, 2023 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-36323650
10.
Discovery of novel HDAC8 inhibitors from natural compounds by in silico high throughput screening.
J Biomol Struct Dyn
; 41(19): 9492-9502, 2023 11.
Artículo
en Inglés
| MEDLINE | ID: mdl-36369945
11.
A comprehensive review on glucokinase activators: Promising agents for the treatment of Type 2 diabetes.
Chem Biol Drug Des
; 99(2): 247-263, 2022 02.
Artículo
en Inglés
| MEDLINE | ID: mdl-34714587
12.
Antiviral activities of natural compounds and ionic liquids to inhibit the Mpro of SARS-CoV-2: a computational approach.
RSC Adv
; 12(6): 3687-3695, 2022 Jan 24.
Artículo
en Inglés
| MEDLINE | ID: mdl-35425367
13.
Synthesis and properties of triazole-linked RNA.
Bioorg Med Chem Lett
; 21(11): 3420-2, 2011 Jun 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-21524577
14.
Synergistic effects of curcumin and its analogs with other bioactive compounds: A comprehensive review.
Eur J Med Chem
; 210: 113072, 2021 Jan 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-33310285
15.
Electrophysiological and behavioral evidence that modulation of metabotropic glutamate receptor 4 with a new agonist reverses experimental parkinsonism.
FASEB J
; 23(10): 3619-28, 2009 Oct.
Artículo
en Inglés
| MEDLINE | ID: mdl-19525404
16.
Targeting severe acute respiratory syndrome-coronavirus (SARS-CoV-1) with structurally diverse inhibitors: a comprehensive review.
RSC Adv
; 10(47): 28287-28299, 2020 Jul 27.
Artículo
en Inglés
| MEDLINE | ID: mdl-35519094
17.
Discovery of Vascular Endothelial Growth Factor Receptor-2 (VEGFR-2) Inhibitors by Ligand-based Virtual High Throughput Screening.
Mol Inform
; 39(7): e1900150, 2020 07.
Artículo
en Inglés
| MEDLINE | ID: mdl-32147949
18.
Metabotropic glutamate receptor subtype 4 selectively modulates both glutamate and GABA transmission in the striatum: implications for Parkinson's disease treatment.
J Neurochem
; 109(4): 1096-105, 2009 May.
Artículo
en Inglés
| MEDLINE | ID: mdl-19519781
19.
Molecular mechanisms of curcumin and its analogs in colon cancer prevention and treatment.
Life Sci
; 239: 117032, 2019 Dec 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-31704450
20.
Synthesis, evaluation of cytotoxic properties of promising curcumin analogues and investigation of possible molecular mechanisms.
Chem Biol Drug Des
; 91(1): 332-337, 2018 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-28649799