Detalles de la búsqueda
1.
Significant impact of time-of-day variation on metformin pharmacokinetics.
Diabetologia
; 66(6): 1024-1034, 2023 06.
Artículo
en Inglés
| MEDLINE | ID: mdl-36930251
2.
Physiologically based pharmacokinetic modeling of imatinib and N-desmethyl imatinib for drug-drug interaction predictions.
CPT Pharmacometrics Syst Pharmacol
; 13(6): 926-940, 2024 Jun.
Artículo
en Inglés
| MEDLINE | ID: mdl-38482980
3.
A physiologically-based pharmacokinetic precision dosing approach to manage dasatinib drug-drug interactions.
CPT Pharmacometrics Syst Pharmacol
; 2024 May 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-38693610
4.
Personalized Chronomodulated 5-Fluorouracil Treatment: A Physiologically-Based Pharmacokinetic Precision Dosing Approach for Optimizing Cancer Therapy.
Clin Pharmacol Ther
; 115(6): 1282-1292, 2024 Jun.
Artículo
en Inglés
| MEDLINE | ID: mdl-38264789
5.
Physiologically Based Pharmacokinetic Modeling of Bergamottin and 6,7-Dihydroxybergamottin to Describe CYP3A4 Mediated Grapefruit-Drug Interactions.
Clin Pharmacol Ther
; 114(2): 470-482, 2023 08.
Artículo
en Inglés
| MEDLINE | ID: mdl-37307228
6.
A Physiologically Based Pharmacokinetic Model of Ketoconazole and Its Metabolites as Drug-Drug Interaction Perpetrators.
Pharmaceutics
; 15(2)2023 Feb 17.
Artículo
en Inglés
| MEDLINE | ID: mdl-36840001
7.
Physiologically based pharmacokinetic modeling of tacrolimus for food-drug and CYP3A drug-drug-gene interaction predictions.
CPT Pharmacometrics Syst Pharmacol
; 12(5): 724-738, 2023 05.
Artículo
en Inglés
| MEDLINE | ID: mdl-36808892
8.
Physiologically-based pharmacokinetic modeling of quinidine to establish a CYP3A4, P-gp, and CYP2D6 drug-drug-gene interaction network.
CPT Pharmacometrics Syst Pharmacol
; 12(8): 1143-1156, 2023 08.
Artículo
en Inglés
| MEDLINE | ID: mdl-37165978
9.
Motivations for Adolescent COVID-19 Vaccination: A Comparative Study of Adolescent and Caregiver Perspectives in Germany.
Children (Basel)
; 10(12)2023 Dec 06.
Artículo
en Inglés
| MEDLINE | ID: mdl-38136092
10.
A dynamic time-to-event model for prediction of acute graft-versus-host disease in patients after allogeneic hematopoietic stem cell transplantation.
Cancer Med
; 2023 Dec 22.
Artículo
en Inglés
| MEDLINE | ID: mdl-38132807
11.
Influence of the application area on finite dose permeation in relation to drug type applied.
Exp Dermatol
; 21(3): 233-5, 2012 Mar.
Artículo
en Inglés
| MEDLINE | ID: mdl-22379974
12.
Physiologically-based pharmacokinetic modeling of dextromethorphan to investigate interindividual variability within CYP2D6 activity score groups.
CPT Pharmacometrics Syst Pharmacol
; 11(4): 494-511, 2022 04.
Artículo
en Inglés
| MEDLINE | ID: mdl-35257505
13.
Physiologically Based Pharmacokinetic (PBPK) Modeling of Clopidogrel and Its Four Relevant Metabolites for CYP2B6, CYP2C8, CYP2C19, and CYP3A4 Drug-Drug-Gene Interaction Predictions.
Pharmaceutics
; 14(5)2022 Apr 22.
Artículo
en Inglés
| MEDLINE | ID: mdl-35631502
14.
Renal Transporter-Mediated Drug-Biomarker Interactions of the Endogenous Substrates Creatinine and N1 -Methylnicotinamide: A PBPK Modeling Approach.
Clin Pharmacol Ther
; 112(3): 687-698, 2022 09.
Artículo
en Inglés
| MEDLINE | ID: mdl-35527512
15.
A Physiologically Based Pharmacokinetic and Pharmacodynamic Model of the CYP3A4 Substrate Felodipine for Drug-Drug Interaction Modeling.
Pharmaceutics
; 14(7)2022 Jul 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-35890369
16.
In Vitro-In Silico Modeling of Caffeine and Diclofenac Permeation in Static and Fluidic Systems with a 16HBE Lung Cell Barrier.
Pharmaceuticals (Basel)
; 15(2)2022 Feb 18.
Artículo
en Inglés
| MEDLINE | ID: mdl-35215362
17.
Physiologically Based Pharmacokinetic Modeling to Describe the CYP2D6 Activity Score-Dependent Metabolism of Paroxetine, Atomoxetine and Risperidone.
Pharmaceutics
; 14(8)2022 Aug 18.
Artículo
en Inglés
| MEDLINE | ID: mdl-36015360
18.
Pharmacometric Modeling of the Impact of Azelastine Nasal Spray on SARS-CoV-2 Viral Load and Related Symptoms in COVID-19 Patients.
Pharmaceutics
; 14(10)2022 Sep 27.
Artículo
en Inglés
| MEDLINE | ID: mdl-36297492
19.
Model-Based Analysis of SARS-CoV-2 Infections, Hospitalization and Outcome in Germany, the Federal States and Districts.
Viruses
; 14(10)2022 09 24.
Artículo
en Inglés
| MEDLINE | ID: mdl-36298669
20.
Prediction of Drug-Drug-Gene Interaction Scenarios of (E)-Clomiphene and Its Metabolites Using Physiologically Based Pharmacokinetic Modeling.
Pharmaceutics
; 14(12)2022 Nov 25.
Artículo
en Inglés
| MEDLINE | ID: mdl-36559098