Detalles de la búsqueda
1.
A phase 1 safety and bioimaging trial of antibody DS-8895a against EphA2 in patients with advanced or metastatic EphA2 positive cancers.
Invest New Drugs
; 40(4): 747-755, 2022 08.
Artículo
en Inglés
| MEDLINE | ID: mdl-35404015
2.
First-in-human study of the anti-HB-EGF antibody U3-1565 in subjects with advanced solid tumors.
Invest New Drugs
; 37(1): 147-158, 2019 02.
Artículo
en Inglés
| MEDLINE | ID: mdl-30056611
3.
Phase 1 Study To Assess the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of Multiple Oral Doses of DS-2969b, a Novel GyrB Inhibitor, in Healthy Subjects.
Antimicrob Agents Chemother
; 62(5)2018 05.
Artículo
en Inglés
| MEDLINE | ID: mdl-29439973
4.
First-in-human study of the antibody DR5 agonist DS-8273a in patients with advanced solid tumors.
Invest New Drugs
; 35(3): 298-306, 2017 06.
Artículo
en Inglés
| MEDLINE | ID: mdl-28050790
5.
U.S. Phase I First-in-human Study of Taletrectinib (DS-6051b/AB-106), a ROS1/TRK Inhibitor, in Patients with Advanced Solid Tumors.
Clin Cancer Res
; 26(18): 4785-4794, 2020 09 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-32591465
6.
Open-Label Single-Dose Study to Assess the Effect of Mild and Moderate Hepatic Impairment on the Pharmacokinetics of Mirogabalin.
Clin Drug Investig
; 38(11): 1001-1009, 2018 Nov.
Artículo
en Inglés
| MEDLINE | ID: mdl-30171457
7.
A Phase I, Single-Ascending-Dose Study in Healthy Subjects to Assess the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of DS-2969b, a Novel GyrB Inhibitor.
J Clin Pharmacol
; 58(12): 1557-1565, 2018 12.
Artículo
en Inglés
| MEDLINE | ID: mdl-29746725
8.
Molecular imaging of T cell co-regulator factor B7-H3 with 89Zr-DS-5573a.
Theranostics
; 8(15): 4199-4209, 2018.
Artículo
en Inglés
| MEDLINE | ID: mdl-30128047
9.
A Phase 1 Study to Assess the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of Single Oral Doses of DS-3801b, a Motilin Receptor Agonist, in Healthy Subjects.
J Clin Pharmacol
; 57(9): 1221-1230, 2017 09.
Artículo
en Inglés
| MEDLINE | ID: mdl-28464321
10.
Molecular Imaging and Quantitation of EphA2 Expression in Xenograft Models with 89Zr-DS-8895a.
J Nucl Med
; 57(6): 974-80, 2016 06.
Artículo
en Inglés
| MEDLINE | ID: mdl-26940768
11.
In Vitro and In Vivo Evaluation of 89Zr-DS-8273a as a Theranostic for Anti-Death Receptor 5 Therapy.
Theranostics
; 6(12): 2225-2234, 2016.
Artículo
en Inglés
| MEDLINE | ID: mdl-27924159
12.
Novel neurotrophin-1/B cell-stimulating factor-3 (cardiotrophin-like cytokine) stimulates corticotroph function via a signal transducer and activator of transcription-dependent mechanism negatively regulated by suppressor of cytokine signaling-3.
Endocrinology
; 144(4): 1202-10, 2003 Apr.
Artículo
en Inglés
| MEDLINE | ID: mdl-12639901
13.
Granulocyte colony-stimulating factor decreases tumor necrosis factor production in whole blood: role of interleukin-10 and prostaglandin E(2).
Eur Cytokine Netw
; 15(4): 323-6, 2004.
Artículo
en Inglés
| MEDLINE | ID: mdl-15627641
14.
TNFalpha in experimental diseases of the CNS.
Methods Mol Med
; 98: 171-90, 2004.
Artículo
en Inglés
| MEDLINE | ID: mdl-15064439
15.
Regulatory effects of osteoprotegerin on cellular and humoral immune responses.
Clin Immunol
; 109(3): 347-54, 2003 Dec.
Artículo
en Inglés
| MEDLINE | ID: mdl-14697750
16.
Pretreatment with granulocyte-colony stimulating factor decreases lipopolysaccharide-induced interferon-gamma production in mice in association with the production of interleukin-18.
Cytokine
; 25(3): 119-26, 2004 Feb 07.
Artículo
en Inglés
| MEDLINE | ID: mdl-14698138
17.
Frontline: interferon regulatory factor-1 as a protective gene in intestinal inflammation: role of TCR gamma delta T cells and interleukin-18-binding protein.
Eur J Immunol
; 34(9): 2356-64, 2004 Sep.
Artículo
en Inglés
| MEDLINE | ID: mdl-15307168
18.
Pulmonary inflammation induced by Pseudomonas aeruginosa lipopolysaccharide, phospholipase C, and exotoxin A: role of interferon regulatory factor 1.
Infect Immun
; 70(3): 1352-8, 2002 Mar.
Artículo
en Inglés
| MEDLINE | ID: mdl-11854220
19.
Mechanisms of inhibition of collagen-induced arthritis by murine IL-18 binding protein.
J Immunol
; 170(4): 2100-5, 2003 Feb 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-12574381
20.
Comparative study of gp130 cytokine effects on corticotroph AtT-20 cells--redundancy or specificity of neuroimmunoendocrine modulators?
Neuroimmunomodulation
; 11(4): 224-32, 2004.
Artículo
en Inglés
| MEDLINE | ID: mdl-15249728