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1.
Metabotropic glutamate receptor 5 (mGlu5 )-positive allosteric modulators differentially induce or potentiate desensitization of mGlu5 signaling in recombinant cells and neurons.
J Neurochem
; 151(3): 301-315, 2019 11.
Artículo
en Inglés
| MEDLINE | ID: mdl-31376155
2.
Differential contribution of metabotropic glutamate receptor 5 common allosteric binding site residues to biased allosteric agonism.
Biochem Pharmacol
; 177: 114011, 2020 07.
Artículo
en Inglés
| MEDLINE | ID: mdl-32380090
3.
Probe dependence and biased potentiation of metabotropic glutamate receptor 5 is mediated by differential ligand interactions in the common allosteric binding site.
Biochem Pharmacol
; 177: 114013, 2020 07.
Artículo
en Inglés
| MEDLINE | ID: mdl-32389635
4.
Kinetic and system bias as drivers of metabotropic glutamate receptor 5 allosteric modulator pharmacology.
Neuropharmacology
; 149: 83-96, 2019 05 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-30763654
5.
Biased allosteric agonism and modulation of metabotropic glutamate receptor 5: Implications for optimizing preclinical neuroscience drug discovery.
Neuropharmacology
; 115: 60-72, 2017 03 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-27392634
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