Detalles de la búsqueda
1.
LC/Q-TOF-MS-based structural characterization of enasidenib degradation products and establishment of a stability-indicating assay method: Insights into chemical stability.
Rapid Commun Mass Spectrom
; 38(5): e9696, 2024 Mar 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-38355880
2.
Delineation of prototypical degradation mechanism, characterization of unknown degradation impurities by liquid chromatography-quadrupole-time-of-flight-tandem mass spectrometry and stability-indicating analytical method of selumetinib.
Biomed Chromatogr
; 38(1): e5761, 2024 Jan.
Artículo
en Inglés
| MEDLINE | ID: mdl-37920143
3.
Differential role of potential stressors, underlying degradation mechanism, characterization of degradants using LC-MS/MS, and establishment of a stability-indicating analytical method for duvelisib.
Biomed Chromatogr
; 38(1): e5760, 2024 Jan.
Artículo
en Inglés
| MEDLINE | ID: mdl-37852619
4.
Ultra-high-performance liquid chromatography-quadrupole time of flight tandem mass spectrometry based in vitro metabolite profiling of DK-GV-04P, a novel anticancer molecule under drug discovery.
Biomed Chromatogr
; 38(3): e5806, 2024 Mar.
Artículo
en Inglés
| MEDLINE | ID: mdl-38087453
5.
Unveiling genotypic diversity of Theileria orientalis in lethal outbreaks among bovines in Karnataka, India.
Parasitol Res
; 123(5): 202, 2024 May 04.
Artículo
en Inglés
| MEDLINE | ID: mdl-38703234
6.
Comprehensive characterization and preclinical assessment of an imidazopyridine-based anticancer lead molecule.
Drug Dev Res
; 85(1): e22139, 2024 Feb.
Artículo
en Inglés
| MEDLINE | ID: mdl-38084651
7.
LC-QQQ-MS based intracellular quantification of bictegravir in peripheral blood mononuclear cells and plasma.
Anal Biochem
; 667: 115084, 2023 04 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-36806669
8.
Mechanism of capmatinib degradation in stress conditions including degradation product characterization using ultra-high-performance liquid chromatography-quadrupole-time of flight mass spectrometry and stability-indicating analytical method development.
Rapid Commun Mass Spectrom
; 37(1): e9417, 2023 Jan 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-36226771
9.
Molecular and genetic diversity in isolates of Trypanosoma evansi from naturally infected horse and dogs by using RoTat 1.2 VSG gene in Madhya Pradesh, India.
Mol Biol Rep
; 50(9): 7347-7356, 2023 Sep.
Artículo
en Inglés
| MEDLINE | ID: mdl-37439897
10.
Assessment of metabolic stability and pharmacokinetics by LC-MS/MS and establishment of the safe dose of IMID-2, a novel anticancer molecule under drug discovery.
Biomed Chromatogr
; 37(6): e5618, 2023 Jun.
Artículo
en Inglés
| MEDLINE | ID: mdl-36882885
11.
Cutting-edge strategies and critical advancements in characterization and quantification of metabolites concerning translational metabolomics.
Drug Metab Rev
; 54(4): 401-426, 2022 11.
Artículo
en Inglés
| MEDLINE | ID: mdl-36351878
12.
Implication of metabolomics and transporter modulation based strategies to minimize multidrug resistance and enhance site-specific bioavailability: a needful consideration toward modern anticancer drug discovery.
Drug Metab Rev
; 54(2): 101-119, 2022 05.
Artículo
en Inglés
| MEDLINE | ID: mdl-35254954
13.
High resolution mass spectrometry-driven metabolite profiling of baricitinib to report its unknown metabolites and step-by-step reaction mechanism of metabolism.
Rapid Commun Mass Spectrom
; 36(22): e9385, 2022 Nov 30.
Artículo
en Inglés
| MEDLINE | ID: mdl-36018833
14.
UHPLC-Q-TOF-MS/MS-based metabolite profiling of duvelisib and establishment of its metabolism mechanisms.
Biomed Chromatogr
; 36(4): e5314, 2022 Apr.
Artículo
en Inglés
| MEDLINE | ID: mdl-34981541
15.
Direct Observation of Magnon-Phonon Strong Coupling in Two-Dimensional Antiferromagnet at High Magnetic Fields.
Phys Rev Lett
; 127(9): 097401, 2021 Aug 27.
Artículo
en Inglés
| MEDLINE | ID: mdl-34506201
16.
Metabolite profiling of IMID-2, a novel anticancer molecule of piperazine derivative: In silico prediction, in vitro and in vivo metabolite characterization using UPLC-QTOF-MS/MS.
Biomed Chromatogr
; 35(6): e5082, 2021 Jun.
Artículo
en Inglés
| MEDLINE | ID: mdl-33570183
17.
Investigation of the impact of grapefruit juice, pomegranate juice and tomato juice on pharmacokinetics of brexpiprazole in rats using UHPLC-QTOF-MS.
Biomed Chromatogr
; 35(11): e5201, 2021 Nov.
Artículo
en Inglés
| MEDLINE | ID: mdl-34148241
18.
Simultaneous quantification of abemaciclib and letrozole in rat plasma: method development, validation and pharmacokinetic application.
Biomed Chromatogr
; 34(6): e4825, 2020 Jun.
Artículo
en Inglés
| MEDLINE | ID: mdl-32166756
19.
3-Nitrotyrosine: a versatile oxidative stress biomarker for major neurodegenerative diseases.
Int J Neurosci
; 130(10): 1047-1062, 2020 Oct.
Artículo
en Inglés
| MEDLINE | ID: mdl-31914343
20.
Simultaneous bioanalysis and pharmacokinetic interaction study of acebrophylline, levocetirizine and pranlukast in Sprague-Dawley rats.
Biomed Chromatogr
; 33(12): e4672, 2019 Dec.
Artículo
en Inglés
| MEDLINE | ID: mdl-31386207