Detalles de la búsqueda
1.
Identification, characterization and evaluation of novel antifungal cyclic peptides from Neobacillus drentensis.
Bioorg Chem
; 115: 105180, 2021 10.
Artículo
en Inglés
| MEDLINE | ID: mdl-34332234
2.
Newly Developed Dopamine D3 Receptor Antagonists, R-VK4-40 and R-VK4-116, Do Not Potentiate Cardiovascular Effects of Cocaine or Oxycodone in Rats.
J Pharmacol Exp Ther
; 371(3): 602-614, 2019 12.
Artículo
en Inglés
| MEDLINE | ID: mdl-31562201
3.
Design, synthesis of phenstatin/isocombretastatin-oxindole conjugates as antimitotic agents.
Bioorg Med Chem
; 24(8): 1729-40, 2016 Apr 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-26970659
4.
Design and synthesis of pyrazole/isoxazole linked arylcinnamides as tubulin polymerization inhibitors and potential antiproliferative agents.
Org Biomol Chem
; 13(40): 10162-78, 2015 Oct 28.
Artículo
en Inglés
| MEDLINE | ID: mdl-26303171
5.
Synthesis and biological evaluation of novel pyrano[3,2-c]carbazole derivatives as anti-tumor agents inducing apoptosis via tubulin polymerization inhibition.
Org Biomol Chem
; 13(5): 1404-14, 2015 Feb 07.
Artículo
en Inglés
| MEDLINE | ID: mdl-25467166
6.
Synthesis of phenstatin/isocombretastatin-chalcone conjugates as potent tubulin polymerization inhibitors and mitochondrial apoptotic inducers.
Org Biomol Chem
; 13(13): 3963-81, 2015 Apr 07.
Artículo
en Inglés
| MEDLINE | ID: mdl-25721862
7.
Synthesis of (Z)-(arylamino)-pyrazolyl/isoxazolyl-2-propenones as tubulin targeting anticancer agents and apoptotic inducers.
Org Biomol Chem
; 13(11): 3416-31, 2015 Mar 21.
Artículo
en Inglés
| MEDLINE | ID: mdl-25661328
8.
Synthesis of arylpyrazole linked benzimidazole conjugates as potential microtubule disruptors.
Bioorg Med Chem
; 23(5): 1082-95, 2015 Mar 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-25648686
9.
Synthesis of ß-carboline-benzimidazole conjugates using lanthanum nitrate as a catalyst and their biological evaluation.
Org Biomol Chem
; 12(15): 2370-87, 2014 Apr 21.
Artículo
en Inglés
| MEDLINE | ID: mdl-24604306
10.
Pyrazole-oxadiazole conjugates: synthesis, antiproliferative activity and inhibition of tubulin polymerization.
Org Biomol Chem
; 12(40): 7993-8007, 2014 Oct 28.
Artículo
en Inglés
| MEDLINE | ID: mdl-25181296
11.
Synthesis of Monofluorinated 7-Hydroxycoumarin-3-Carboxamides as Cell-Permeable Fluorescent Molecular Probes.
ACS Med Chem Lett
; 15(5): 677-683, 2024 May 09.
Artículo
en Inglés
| MEDLINE | ID: mdl-38746887
12.
Paralogue-selective degradation of the lysine acetyltransferase EP300.
bioRxiv
; 2024 May 05.
Artículo
en Inglés
| MEDLINE | ID: mdl-38746397
13.
Dopamine D3/D2 Receptor Ligands Based on Cariprazine for the Treatment of Psychostimulant Use Disorders That May Be Dual Diagnosed with Affective Disorders.
J Med Chem
; 66(3): 1809-1834, 2023 02 09.
Artículo
en Inglés
| MEDLINE | ID: mdl-36661568
14.
A highly D3R-selective and efficacious partial agonist (S)-ABS01-113 compared to its D3R-selective antagonist enantiomer (R)-ABS01-113 as potential treatments for opioid use disorder.
Neuropsychopharmacology
; 47(13): 2309-2318, 2022 12.
Artículo
en Inglés
| MEDLINE | ID: mdl-35879349
15.
Structure Activity Relationships for a Series of Eticlopride-Based Dopamine D2/D3 Receptor Bitopic Ligands.
J Med Chem
; 64(20): 15313-15333, 2021 10 28.
Artículo
en Inglés
| MEDLINE | ID: mdl-34636551
16.
Novel Dual-Target µ-Opioid Receptor and Dopamine D3 Receptor Ligands as Potential Nonaddictive Pharmacotherapeutics for Pain Management.
J Med Chem
; 64(11): 7778-7808, 2021 06 10.
Artículo
en Inglés
| MEDLINE | ID: mdl-34011153
17.
Synthesis of new bis-pyrazole linked hydrazides and their in vitro evaluation as antimicrobial and anti-biofilm agents: A mechanistic role on ergosterol biosynthesis inhibition in Candida albicans.
Chem Biol Drug Des
; 94(1): 1339-1351, 2019 07.
Artículo
en Inglés
| MEDLINE | ID: mdl-30803151
18.
Investigation of Novel Primary and Secondary Pharmacophores and 3-Substitution in the Linking Chain of a Series of Highly Selective and Bitopic Dopamine D3 Receptor Antagonists and Partial Agonists.
J Med Chem
; 62(20): 9061-9077, 2019 10 24.
Artículo
en Inglés
| MEDLINE | ID: mdl-31526003
19.
Design, synthesis, in silico pharmacokinetics prediction and biological evaluation of 1,4-dihydroindeno[1,2-c]pyrazole chalcone as EGFR /Akt pathway inhibitors.
Eur J Med Chem
; 163: 636-648, 2019 Feb 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-30562699
20.
The Significance of Chirality in Drug Design and Synthesis of Bitopic Ligands as D3 Receptor (D3R) Selective Agonists.
J Med Chem
; 62(13): 6287-6314, 2019 07 11.
Artículo
en Inglés
| MEDLINE | ID: mdl-31257877