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1.
DNA-PKcs and ATM modulate mitochondrial ADP-ATP exchange as an oxidative stress checkpoint mechanism.
EMBO J
; 42(6): e112094, 2023 03 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-36727301
2.
Vanillin derivative VND3207 activates DNA-PKcs conferring protection against radiation-induced intestinal epithelial cells injury in vitro and in vivo.
Toxicol Appl Pharmacol
; 387: 114855, 2020 01 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-31830491
3.
PIDD mediates the association of DNA-PKcs and ATR at stalled replication forks to facilitate the ATR signaling pathway.
Nucleic Acids Res
; 46(4): 1847-1859, 2018 02 28.
Artículo
en Inglés
| MEDLINE | ID: mdl-29309644
4.
p53-inducible gene 3 promotes cell migration and invasion by activating the FAK/Src pathway in lung adenocarcinoma.
Cancer Sci
; 109(12): 3783-3793, 2018 Dec.
Artículo
en Inglés
| MEDLINE | ID: mdl-30281878
5.
The vanillin derivative 6-bromine-5-hydroxy-4-methoxybenzaldehyde induces aberrant mitotic progression and enhances radio-sensitivity accompanying suppression the expression of PLK1 in esophageal squamous cell carcinoma.
Toxicol Appl Pharmacol
; 348: 76-84, 2018 06 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-29679654
6.
Tumor suppressor protein DAB2IP participates in chromosomal stability maintenance through activating spindle assembly checkpoint and stabilizing kinetochore-microtubule attachments.
Nucleic Acids Res
; 44(18): 8842-8854, 2016 Oct 14.
Artículo
en Inglés
| MEDLINE | ID: mdl-27568005
7.
Phosphorylation of ETS-1 is a critical event in DNA polymerase iota-induced invasion and metastasis of esophageal squamous cell carcinoma.
Cancer Sci
; 108(12): 2503-2510, 2017 Dec.
Artículo
en Inglés
| MEDLINE | ID: mdl-28905458
8.
Stabilization of 4E-BP1 by PI3K kinase and its involvement in CHK2 phosphorylation in the cellular response to radiation.
Int J Med Sci
; 14(5): 452-461, 2017.
Artículo
en Inglés
| MEDLINE | ID: mdl-28539821
9.
DNA-PKcs is required to maintain stability of Chk1 and Claspin for optimal replication stress response.
Nucleic Acids Res
; 42(7): 4463-73, 2014 Apr.
Artículo
en Inglés
| MEDLINE | ID: mdl-24500207
10.
The involvement of c-Myc in the DNA double-strand break repair via regulating radiation-induced phosphorylation of ATM and DNA-PKcs activity.
Mol Cell Biochem
; 406(1-2): 43-51, 2015 Aug.
Artículo
en Inglés
| MEDLINE | ID: mdl-26049366
11.
DNA-PKcs associates with PLK1 and is involved in proper chromosome segregation and cytokinesis.
J Cell Biochem
; 115(6): 1077-88, 2014 Jun.
Artículo
en Inglés
| MEDLINE | ID: mdl-24166892
12.
Nanodrugs with intrinsic radioprotective exertion: Turning the double-edged sword into a single-edged knife.
Exploration (Beijing)
; 3(2): 20220119, 2023 Apr.
Artículo
en Inglés
| MEDLINE | ID: mdl-37324033
13.
Polymerase iota (POLI) confers radioresistance of esophageal squamous cell carcinoma by regulating RAD51 stability and facilitating homologous recombination.
Cell Death Discov
; 9(1): 291, 2023 Aug 09.
Artículo
en Inglés
| MEDLINE | ID: mdl-37558683
14.
Black Phosphorus Quantum Dots Enhance the Radiosensitivity of Human Renal Cell Carcinoma Cells through Inhibition of DNA-PKcs Kinase.
Cells
; 11(10)2022 05 16.
Artículo
en Inglés
| MEDLINE | ID: mdl-35626687
15.
TAB182 aggravates progression of esophageal squamous cell carcinoma by enhancing ß-catenin nuclear translocation through FHL2 dependent manner.
Cell Death Dis
; 13(10): 900, 2022 10 26.
Artículo
en Inglés
| MEDLINE | ID: mdl-36289198
16.
Mitotic phosphorylation of tumor suppressor DAB2IP maintains spindle assembly checkpoint and chromosomal stability through activating PLK1-Mps1 signal pathway and stabilizing mitotic checkpoint complex.
Oncogene
; 41(4): 489-501, 2022 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-34775484
17.
Proteomic profiling revealed the functional networks associated with mitotic catastrophe of HepG2 hepatoma cells induced by 6-bromine-5-hydroxy-4-methoxybenzaldehyde.
Toxicol Appl Pharmacol
; 252(3): 307-17, 2011 May 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-21419150
18.
DNA-PKcs inhibition impairs HDAC6-mediated HSP90 chaperone function on Aurora A and enhances HDACs inhibitor-induced cell killing by increasing mitotic aberrant spindle assembly.
Cell Cycle
; 20(2): 211-224, 2021 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-33404279
19.
Feedback activation of STAT3 limits the response to PI3K/AKT/mTOR inhibitors in PTEN-deficient cancer cells.
Oncogenesis
; 10(1): 8, 2021 Jan 05.
Artículo
en Inglés
| MEDLINE | ID: mdl-33431808
20.
DNA-PKcs plays a dominant role in the regulation of H2AX phosphorylation in response to DNA damage and cell cycle progression.
BMC Mol Biol
; 11: 18, 2010 Mar 06.
Artículo
en Inglés
| MEDLINE | ID: mdl-20205745