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1.
Pharmacophore-based design and discovery of (-)-meptazinol carbamates as dual modulators of cholinesterase and amyloidogenesis.
J Enzyme Inhib Med Chem
; 32(1): 659-671, 2017 Dec.
Artículo
en Inglés
| MEDLINE | ID: mdl-28274151
2.
A novel assay to determine acetylcholinesterase activity: The application potential for screening of drugs against Alzheimer's disease.
Biomed Chromatogr
; 31(10)2017 Oct.
Artículo
en Inglés
| MEDLINE | ID: mdl-28295437
3.
Novel bis-(-)-nor-meptazinol derivatives act as dual binding site AChE inhibitors with metal-complexing property.
Toxicol Appl Pharmacol
; 264(1): 65-72, 2012 Oct 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-22842334
4.
Pilocarpine protects cobalt chloride-induced apoptosis of RGC-5 cells: involvement of muscarinic receptors and HIF-1 alpha pathway.
Cell Mol Neurobiol
; 30(3): 427-35, 2010 Apr.
Artículo
en Inglés
| MEDLINE | ID: mdl-19816768
5.
Muscarinic activation attenuates abnormal processing of beta-amyloid precursor protein induced by cobalt chloride-mimetic hypoxia in retinal ganglion cells.
Biochem Biophys Res Commun
; 384(1): 110-3, 2009 Jun 19.
Artículo
en Inglés
| MEDLINE | ID: mdl-19393223
6.
Novel piperazine derivative PMS1339 exhibits tri-functional properties and cognitive improvement in mice.
Int J Neuropsychopharmacol
; 12(10): 1409-19, 2009 Nov.
Artículo
en Inglés
| MEDLINE | ID: mdl-19460190
7.
Protection of PMS777, a new AChE inhibitor with PAF antagonism, against amyloid-beta-induced neuronal apoptosis and neuroinflammation.
Cell Mol Neurobiol
; 29(4): 589-95, 2009 Jun.
Artículo
en Inglés
| MEDLINE | ID: mdl-19194797
8.
Peripheral cholinoceptor antagonist anisodamine counteracts cholinergic adverse effects and facilitates cognitive amelioration of rivastigmine.
J Neural Transm (Vienna)
; 116(12): 1643-9, 2009 Dec.
Artículo
en Inglés
| MEDLINE | ID: mdl-19756370
9.
PMS777, a bis-interacting ligand for PAF receptor antagonism and AChE inhibition, attenuates PAF-induced neurocytotoxicity in SH-SY5Y cells.
Cell Mol Neurobiol
; 28(1): 125-36, 2008 Jan.
Artículo
en Inglés
| MEDLINE | ID: mdl-17712622
10.
Determination of a novel carbamate AChE inhibitor meserine in mouse plasma, brain and rat plasma by LC-MS/MS: application to pharmacokinetic study after intravenous and subcutaneous administration.
J Pharm Biomed Anal
; 96: 156-61, 2014 Aug 05.
Artículo
en Inglés
| MEDLINE | ID: mdl-24747147
11.
Meserine, a novel carbamate AChE inhibitor, ameliorates scopolamine-induced dementia and alleviates amyloidogenesis of APP/PS1 transgenic mice.
CNS Neurosci Ther
; 20(2): 165-71, 2014 Feb.
Artículo
en Inglés
| MEDLINE | ID: mdl-24279603
12.
Surrogate based accurate quantification of endogenous acetylcholine in murine brain by hydrophilic interaction liquid chromatography-tandem mass spectrometry.
J Chromatogr B Analyt Technol Biomed Life Sci
; 879(32): 3927-31, 2011 Dec 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-22088352
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