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1.
Discovery of dapagliflozin: a potent, selective renal sodium-dependent glucose cotransporter 2 (SGLT2) inhibitor for the treatment of type 2 diabetes.
J Med Chem
; 51(5): 1145-9, 2008 Mar 13.
Artículo
en Inglés
| MEDLINE | ID: mdl-18260618
2.
Aglycone exploration of C-arylglucoside inhibitors of renal sodium-dependent glucose transporter SGLT2.
Bioorg Med Chem Lett
; 18(17): 4770-3, 2008 Sep 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-18707880
3.
Utilization of an Active Site Mutant Receptor for the Identification of Potent and Selective Atypical 5-HT2C Receptor Agonists.
J Med Chem
; 60(14): 6166-6190, 2017 07 27.
Artículo
en Inglés
| MEDLINE | ID: mdl-28635286
4.
Reductions in log P improved protein binding and clearance predictions enabling the prospective design of cannabinoid receptor (CB1) antagonists with desired pharmacokinetic properties.
J Med Chem
; 56(23): 9586-600, 2013 Dec 12.
Artículo
en Inglés
| MEDLINE | ID: mdl-24182233
5.
Addition of benzylic and allylic organozinc and Grignard reagents to resin-bound imines to provide alpha-branched secondary amines bearing a wide variety of functional groups. Utility in the synthesis of beta-3 adrenergic receptor agonists.
J Comb Chem
; 7(1): 99-108, 2005.
Artículo
en Inglés
| MEDLINE | ID: mdl-15638488
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