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Novel Protease Inhibitors Containing C-5-Modified bis-Tetrahydrofuranylurethane and Aminobenzothiazole as P2 and P2' Ligands That Exert Potent Antiviral Activity against Highly Multidrug-Resistant HIV-1 with a High Genetic Barrier against the Emergence of Drug Resistance.
Antimicrob Agents Chemother
; 63(8)2019 08.
Artículo
en Inglés
| MEDLINE | ID: mdl-31085520
2.
A Modified P1 Moiety Enhances In Vitro Antiviral Activity against Various Multidrug-Resistant HIV-1 Variants and In Vitro Central Nervous System Penetration Properties of a Novel Nonpeptidic Protease Inhibitor, GRL-10413.
Antimicrob Agents Chemother
; 60(12): 7046-7059, 2016 12.
Artículo
en Inglés
| MEDLINE | ID: mdl-27620483
3.
Enantioselective synthesis of spliceostatin E and evaluation of biological activity.
Org Lett
; 16(23): 6200-3, 2014 Dec 05.
Artículo
en Inglés
| MEDLINE | ID: mdl-25423085
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