Detalles de la búsqueda
1.
Design and synthesis 1H-Pyrrolo[2,3-b]pyridine derivatives as FLT3 inhibitors for the treatment of Acute myeloid Leukemia.
Bioorg Med Chem
; 100: 117631, 2024 Feb 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-38330848
2.
Discovery of 4-(4-aminophenyl)-6-phenylisoxazolo[3,4-b]pyridine-3-amine derivatives as novel FLT3 covalent inhibitors for the intervention of acute myeloid leukemia.
Drug Dev Res
; 84(2): 296-311, 2023 04.
Artículo
en Inglés
| MEDLINE | ID: mdl-36644989
3.
Synthesis and biological evaluation of 4-(4-aminophenyl)-6-methylisoxazolo[3,4-b] pyridin-3-amine covalent inhibitors as potential agents for the treatment of acute myeloid leukemia.
Bioorg Med Chem
; 70: 116937, 2022 09 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-35863236
4.
Synergistic inhibitory effect of berberine and icotinib on non-small cell lung cancer cells via inducing autophagic cell death and apoptosis.
Apoptosis
; 26(11-12): 639-656, 2021 12.
Artículo
en Inglés
| MEDLINE | ID: mdl-34743246
5.
Design, synthesis and evaluation of 2-amino-imidazol-4-one derivatives as potent ß-site amyloid precursor protein cleaving enzyme 1 (BACE-1) inhibitors.
Bioorg Med Chem Lett
; 29(24): 126772, 2019 12 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-31711785
6.
A novel and efficient synthesis of phenanthrene derivatives via palladium/norbornadiene-catalyzed domino one-pot reaction.
Beilstein J Org Chem
; 15: 291-298, 2019.
Artículo
en Inglés
| MEDLINE | ID: mdl-30800179
7.
Design, synthesis and structure-activity relationship of diaryl-ureas with novel isoxazol[3,4-b]pyridine-3-amino-structure as multi-target inhibitors against receptor tyrosine kinase.
Bioorg Med Chem
; 26(16): 4735-4744, 2018 09 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-30121211
8.
Protective effect of 6-O-methyl-scutellarein on repeated cerebral ischemia/reperfusion in rats.
J Asian Nat Prod Res
; 20(12): 1167-1181, 2018 Dec.
Artículo
en Inglés
| MEDLINE | ID: mdl-28971689
9.
Novel multitarget-directed tacrine derivatives as potential candidates for the treatment of Alzheimer's disease.
J Enzyme Inhib Med Chem
; 32(1): 572-587, 2017 Dec.
Artículo
en Inglés
| MEDLINE | ID: mdl-28133981
10.
Synthesis and Bioactivity Characterization of Scutellarein Sulfonated Derivative.
Molecules
; 22(6)2017 Jun 21.
Artículo
en Inglés
| MEDLINE | ID: mdl-28635646
11.
An Efficient Chemical Synthesis of Scutellarein: An in Vivo Metabolite of Scutellarin.
Molecules
; 21(3): 263, 2016 Feb 25.
Artículo
en Inglés
| MEDLINE | ID: mdl-26927039
12.
Investigation of 6-O-methyl-scutellarein metabolites in rats by ultra-flow liquid chromatography/quadrupole-time-of-flight mass spectrometry.
Pharm Biol
; 54(10): 2158-67, 2016 Oct.
Artículo
en Inglés
| MEDLINE | ID: mdl-26955854
13.
Synthesis of scutellarein derivatives to increase biological activity and water solubility.
Bioorg Med Chem
; 23(21): 6875-84, 2015 Nov 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-26455656
14.
A new and practical synthetic method for the synthesis of 6-O-methyl-scutellarein: one metabolite of scutellarin in vivo.
Int J Mol Sci
; 16(4): 7587-94, 2015 Apr 03.
Artículo
en Inglés
| MEDLINE | ID: mdl-25854429
15.
A new and efficient synthesis of 6-O-methylscutellarein, the major metabolite of the natural medicine scutellarin.
Molecules
; 20(6): 10184-91, 2015 Jun 02.
Artículo
en Inglés
| MEDLINE | ID: mdl-26042857
16.
Synthesis, biological evaluation and SAR analysis of O-alkylated analogs of quercetin for anticancer.
Bioorg Med Chem Lett
; 24(18): 4424-4427, 2014 Sep 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-25139569
17.
Biological evaluation and SAR analysis of O-methylated analogs of quercetin as inhibitors of cancer cell proliferation.
Drug Dev Res
; 75(7): 455-62, 2014 Nov.
Artículo
en Inglés
| MEDLINE | ID: mdl-24976071
18.
Research strategies of small molecules as chemotherapeutics to overcome multiple myeloma resistance.
Eur J Med Chem
; 271: 116435, 2024 May 05.
Artículo
en Inglés
| MEDLINE | ID: mdl-38648728
19.
Unraveling the Promise of RET Inhibitors in Precision Cancer Therapy by Targeting RET Mutations.
J Med Chem
; 67(6): 4346-4375, 2024 Mar 28.
Artículo
en Inglés
| MEDLINE | ID: mdl-38484122
20.
No primexine and plasma membrane undulation is essential for primexine deposition and plasma membrane undulation during microsporogenesis in Arabidopsis.
Plant Physiol
; 158(1): 264-72, 2012 Jan.
Artículo
en Inglés
| MEDLINE | ID: mdl-22100644