Detalles de la búsqueda
1.
Genetic and Functional Analyses Point to FAN1 as the Source of Multiple Huntington Disease Modifier Effects.
Am J Hum Genet
; 107(1): 96-110, 2020 07 02.
Artículo
en Inglés
| MEDLINE | ID: mdl-32589923
2.
Population-specific genetic modification of Huntington's disease in Venezuela.
PLoS Genet
; 14(5): e1007274, 2018 05.
Artículo
en Inglés
| MEDLINE | ID: mdl-29750799
3.
Novel allele-specific quantification methods reveal no effects of adult onset CAG repeats on HTT mRNA and protein levels.
Hum Mol Genet
; 26(7): 1258-1267, 2017 04 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-28165127
4.
Full sequence of mutant huntingtin 3'-untranslated region and modulation of its gene regulatory activity by endogenous microRNA.
J Hum Genet
; 64(10): 995-1004, 2019 Oct.
Artículo
en Inglés
| MEDLINE | ID: mdl-31296921
5.
Permanent inactivation of Huntington's disease mutation by personalized allele-specific CRISPR/Cas9.
Hum Mol Genet
; 25(20): 4566-4576, 2016 10 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-28172889
6.
Personalized allele-specific CRISPR-Cas9 strategies for myofibrillar myopathy 6.
medRxiv
; 2024 Feb 04.
Artículo
en Inglés
| MEDLINE | ID: mdl-38352343
7.
Base editing strategies to convert CAG to CAA diminish the disease-causing mutation in Huntington's disease.
Elife
; 122024 Jun 13.
Artículo
en Inglés
| MEDLINE | ID: mdl-38869243
8.
Thymoquinone inhibits phorbol ester-induced activation of NF-κB and expression of COX-2, and induces expression of cytoprotective enzymes in mouse skin in vivo.
Biochem Biophys Res Commun
; 438(4): 721-7, 2013 Sep 06.
Artículo
en Inglés
| MEDLINE | ID: mdl-23911786
9.
Base editing strategies to convert CAG to CAA diminish the disease-causing mutation in Huntington's disease.
bioRxiv
; 2023 Apr 28.
Artículo
en Inglés
| MEDLINE | ID: mdl-37162872
10.
Haplotype-specific insertion-deletion variations for allele-specific targeting in Huntington's disease.
Mol Ther Methods Clin Dev
; 25: 84-95, 2022 Jun 09.
Artículo
en Inglés
| MEDLINE | ID: mdl-35356757
11.
PAM-altering SNP-based allele-specific CRISPR-Cas9 therapeutic strategies for Huntington's disease.
Mol Ther Methods Clin Dev
; 26: 547-561, 2022 Sep 08.
Artículo
en Inglés
| MEDLINE | ID: mdl-36092363
12.
Allele-specific silencing of the gain-of-function mutation in Huntington's disease using CRISPR/Cas9.
JCI Insight
; 7(19)2022 10 10.
Artículo
en Inglés
| MEDLINE | ID: mdl-36040815
13.
Ultraviolet B radiation activates NF-κB and induces iNOS expression in HR-1 hairless mouse skin: role of IκB kinase-ß.
Mol Carcinog
; 50(4): 310-7, 2011 Apr.
Artículo
en Inglés
| MEDLINE | ID: mdl-21465579
14.
Curcumin induces stabilization of Nrf2 protein through Keap1 cysteine modification.
Biochem Pharmacol
; 173: 113820, 2020 03.
Artículo
en Inglés
| MEDLINE | ID: mdl-31972171
15.
The prospects of CRISPR-based genome engineering in the treatment of neurodegenerative disorders.
Ther Adv Neurol Disord
; 11: 1756285617741837, 2018.
Artículo
en Inglés
| MEDLINE | ID: mdl-29399048
16.
Endogenous ω-3 Fatty Acid Production by fat-1 Transgene and Topically Applied Docosahexaenoic Acid Protect against UVB-induced Mouse Skin Carcinogenesis.
Sci Rep
; 7(1): 11658, 2017 09 14.
Artículo
en Inglés
| MEDLINE | ID: mdl-28912452
17.
Protein tyrosine phosphatases PTP-1B, SHP-2, and PTEN facilitate Rb/E2F-associated apoptotic signaling.
PLoS One
; 9(5): e97104, 2014.
Artículo
en Inglés
| MEDLINE | ID: mdl-24809452
18.
Phloretin inhibits phorbol ester-induced tumor promotion and expression of cyclooxygenase-2 in mouse skin: extracellular signal-regulated kinase and nuclear factor-κB as potential targets.
J Med Food
; 15(3): 253-7, 2012 Mar.
Artículo
en Inglés
| MEDLINE | ID: mdl-22181070
19.
Zerumbone induces heme oxygenase-1 expression in mouse skin and cultured murine epidermal cells through activation of Nrf2.
Cancer Prev Res (Phila)
; 4(6): 860-70, 2011 Jun.
Artículo
en Inglés
| MEDLINE | ID: mdl-21367956
20.
Docosahexaenoic acid inhibits UVB-induced activation of NF-κB and expression of COX-2 and NOX-4 in HR-1 hairless mouse skin by blocking MSK1 signaling.
PLoS One
; 6(11): e28065, 2011.
Artículo
en Inglés
| MEDLINE | ID: mdl-22140508