Detalles de la búsqueda
1.
Effect of rifampin on enantioselective disposition and anti-hypertensive effect of benidipine.
Br J Clin Pharmacol
; 85(4): 737-745, 2019 04.
Artículo
en Inglés
| MEDLINE | ID: mdl-30589098
2.
Genotype-based enrichment study design for minimizing the sample size in bioequivalence studies using tolterodine and CYP2D6 genotypeâ©.
Int J Clin Pharmacol Ther
; 57(2): 110-116, 2019 Feb.
Artículo
en Inglés
| MEDLINE | ID: mdl-30574865
3.
Pharmacokinetic study of metformin to compare voglibose/metformin fixed-dose combination with coadministered voglibose and metformin.
Int J Clin Pharmacol Ther
; 53(2): 147-53, 2015 Feb.
Artículo
en Inglés
| MEDLINE | ID: mdl-25546164
4.
The effect of Ginkgo biloba extracts on the pharmacokinetics and pharmacodynamics of cilostazol and its active metabolites in healthy Korean subjects.
Br J Clin Pharmacol
; 77(5): 821-30, 2014 May.
Artículo
en Inglés
| MEDLINE | ID: mdl-24001154
5.
Effect of voglibose on the pharmacokinetics of metformin in healthy Korean subjects.
Int J Clin Pharmacol Ther
; 52(11): 1005-11, 2014 Nov.
Artículo
en Inglés
| MEDLINE | ID: mdl-25161160
6.
Designs of clinical swallowability assessments of solid oral dosage forms in regulatory submissions.
Int J Pharm
; 659: 124229, 2024 Jun 25.
Artículo
en Inglés
| MEDLINE | ID: mdl-38762166
7.
Effect of HNF4α genetic polymorphism G60D on the pharmacokinetics of CYP2D6 substrate tolterodine in healthy Korean individuals.
Pharmacogenet Genomics
; 23(3): 175-9, 2013 Mar.
Artículo
en Inglés
| MEDLINE | ID: mdl-23292115
8.
Effects of clopidogrel and itraconazole on the disposition of efavirenz and its hydroxyl metabolites: exploration of a novel CYP2B6 phenotyping index.
Br J Clin Pharmacol
; 75(1): 244-53, 2013 Jan.
Artículo
en Inglés
| MEDLINE | ID: mdl-22554354
9.
High-sensitive LC-MS/MS method for the simultaneous determination of mirodenafil and its major metabolite, SK-3541, in human plasma: application to microdose clinical trials of mirodenafil.
J Sep Sci
; 36(5): 840-8, 2013 Mar.
Artículo
en Inglés
| MEDLINE | ID: mdl-23390072
10.
Effects of clopidogrel and clarithromycin on the disposition of sibutramine and its active metabolites M1 and M2 in relation to CYP2B6*6 polymorphism.
Xenobiotica
; 43(2): 211-8, 2013 Feb.
Artículo
en Inglés
| MEDLINE | ID: mdl-22830954
11.
The disposition of three phosphodiesterase type 5 inhibitors, vardenafil, sildenafil, and udenafil, is differently influenced by the CYP3A5 genotype.
Pharmacogenet Genomics
; 21(12): 820-8, 2011 Dec.
Artículo
en Inglés
| MEDLINE | ID: mdl-21934637
12.
Discovery of a novel allelic variant of CYP2C8, CYP2C8*11, in Asian populations and its clinical effect on the rosiglitazone disposition in vivo.
Drug Metab Dispos
; 39(4): 711-6, 2011 Apr.
Artículo
en Inglés
| MEDLINE | ID: mdl-21245287
13.
Serum levels of IL-18 and sIL-2R in patients with alopecia areata receiving combined therapy with oral cyclosporine and steroids.
Exp Dermatol
; 19(2): 145-7, 2010 Feb.
Artículo
en Inglés
| MEDLINE | ID: mdl-19758343
14.
Effects of woohwangcheongsimwon suspension on the pharmacokinetics of bupropion and its active metabolite, 4-hydroxybupropion, in healthy subjects.
Br J Clin Pharmacol
; 70(1): 126-31, 2010 Jul.
Artículo
en Inglés
| MEDLINE | ID: mdl-20642555
15.
Genetic polymorphism of hepatocyte nuclear factor-4alpha influences human cytochrome P450 2D6 activity.
Hepatology
; 48(2): 635-45, 2008 Aug.
Artículo
en Inglés
| MEDLINE | ID: mdl-18666237
16.
Identification of new CYP2C19 variants exhibiting decreased enzyme activity in the metabolism of S-mephenytoin and omeprazole.
Drug Metab Dispos
; 37(11): 2262-9, 2009 Nov.
Artículo
en Inglés
| MEDLINE | ID: mdl-19661214
17.
Liquid chromatography/tandem mass spectrometry method for the simultaneous determination of vardenafil and its major metabolite, N-desethylvardenafil, in human plasma: application to a pharmacokinetic study.
J Chromatogr B Analyt Technol Biomed Life Sci
; 877(1-2): 95-100, 2009 Jan 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-19042162
18.
HPLC determination of irbesartan in human plasma: its application to pharmacokinetic studies.
Biomed Chromatogr
; 23(6): 568-72, 2009 Jun.
Artículo
en Inglés
| MEDLINE | ID: mdl-19277953
19.
Cytochrome P450 2B6 catalyzes the formation of pharmacologically active sibutramine (N-{1-[1-(4-chlorophenyl)cyclobutyl]-3-methylbutyl}-N,N-dimethylamine) metabolites in human liver microsomes.
Drug Metab Dispos
; 36(8): 1679-88, 2008 Aug.
Artículo
en Inglés
| MEDLINE | ID: mdl-18474675
20.
The contributions of cytochromes P450 3A4 and 3A5 to the metabolism of the phosphodiesterase type 5 inhibitors sildenafil, udenafil, and vardenafil.
Drug Metab Dispos
; 36(6): 986-90, 2008 Jun.
Artículo
en Inglés
| MEDLINE | ID: mdl-18308836