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1.
Clinically Observed Estrogen Receptor Alpha Mutations within the Ligand-Binding Domain Confer Distinguishable Phenotypes.
Oncology
; 94(3): 176-189, 2018.
Artículo
en Inglés
| MEDLINE | ID: mdl-29306943
2.
A metric and workflow for quality control in the analysis of heterogeneity in phenotypic profiles and screens.
Methods
; 96: 12-26, 2016 Mar 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-26476369
3.
A Quantitative Systems Pharmacology Platform Reveals NAFLD Pathophysiological States and Targeting Strategies.
Metabolites
; 12(6)2022 Jun 07.
Artículo
en Inglés
| MEDLINE | ID: mdl-35736460
4.
Identification of chemosensitivity nodes for vinblastine through small interfering RNA high-throughput screens.
J Pharmacol Exp Ther
; 339(3): 851-8, 2011 Dec.
Artículo
en Inglés
| MEDLINE | ID: mdl-21880871
5.
Quantifying the progression of non-alcoholic fatty liver disease in human biomimetic liver microphysiology systems with fluorescent protein biosensors.
Exp Biol Med (Maywood)
; 246(22): 2420-2441, 2021 11.
Artículo
en Inglés
| MEDLINE | ID: mdl-33957803
6.
Functional genomic analysis of glioblastoma multiforme through short interfering RNA screening: a paradigm for therapeutic development.
Neurosurg Focus
; 28(1): E4, 2010 Jan.
Artículo
en Inglés
| MEDLINE | ID: mdl-20043719
7.
Development and Optimization of a High-Content Analysis Platform to Identify Suppressors of Lamin B1 Overexpression as a Therapeutic Strategy for Autosomal Dominant Leukodystrophy.
SLAS Discov
; 25(8): 939-949, 2020 09.
Artículo
en Inglés
| MEDLINE | ID: mdl-32349647
8.
Applications of the microphysiology systems database for experimental ADME-Tox and disease models.
Lab Chip
; 20(8): 1472-1492, 2020 04 14.
Artículo
en Inglés
| MEDLINE | ID: mdl-32211684
9.
Identification of survival genes in human glioblastoma cells by small interfering RNA screening.
Mol Pharmacol
; 76(6): 1246-55, 2009 Dec.
Artículo
en Inglés
| MEDLINE | ID: mdl-19783622
10.
A High-Throughput Assay for DNA Replication Inhibitors Based upon Multivariate Analysis of Yeast Growth Kinetics.
SLAS Discov
; 24(6): 669-681, 2019 07.
Artículo
en Inglés
| MEDLINE | ID: mdl-30802412
11.
Development of a 384-well colorimetric assay to quantify hydrogen peroxide generated by the redox cycling of compounds in the presence of reducing agents.
Assay Drug Dev Technol
; 6(4): 505-18, 2008 Aug.
Artículo
en Inglés
| MEDLINE | ID: mdl-18699726
12.
Integrating Analysis of Cellular Heterogeneity in High-Content Dose-Response Studies.
Methods Mol Biol
; 1745: 25-46, 2018.
Artículo
en Inglés
| MEDLINE | ID: mdl-29476461
13.
High Content Imaging Assays for IL-6-Induced STAT3 Pathway Activation in Head and Neck Cancer Cell Lines.
Methods Mol Biol
; 1683: 229-244, 2018.
Artículo
en Inglés
| MEDLINE | ID: mdl-29082496
14.
Development and implementation of a miniaturized high-throughput time-resolved fluorescence energy transfer assay to identify small molecule inhibitors of polo-like kinase 1.
Assay Drug Dev Technol
; 5(6): 723-35, 2007 Dec.
Artículo
en Inglés
| MEDLINE | ID: mdl-18181689
15.
Development and implementation of a 384-well homogeneous fluorescence intensity high-throughput screening assay to identify mitogen-activated protein kinase phosphatase-1 dual-specificity protein phosphatase inhibitors.
Assay Drug Dev Technol
; 5(3): 319-32, 2007 Jun.
Artículo
en Inglés
| MEDLINE | ID: mdl-17638532
16.
HTS identifies novel and specific uncompetitive inhibitors of the two-component NS2B-NS3 proteinase of West Nile virus.
Assay Drug Dev Technol
; 5(6): 737-50, 2007 Dec.
Artículo
en Inglés
| MEDLINE | ID: mdl-18181690
17.
Biologically Relevant Heterogeneity: Metrics and Practical Insights.
SLAS Discov
; 22(3): 213-237, 2017 03.
Artículo
en Inglés
| MEDLINE | ID: mdl-28231035
18.
The Microphysiology Systems Database for Analyzing and Modeling Compound Interactions with Human and Animal Organ Models.
Appl In Vitro Toxicol
; 2(2): 103-117, 2016 Jun 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-28781990
19.
A human liver microphysiology platform for investigating physiology, drug safety, and disease models.
Exp Biol Med (Maywood)
; 241(1): 101-14, 2016 Jan.
Artículo
en Inglés
| MEDLINE | ID: mdl-26202373
20.
HCS campaign to identify selective inhibitors of IL-6-induced STAT3 pathway activation in head and neck cancer cell lines.
Assay Drug Dev Technol
; 13(7): 356-76, 2015 Sep.
Artículo
en Inglés
| MEDLINE | ID: mdl-26317883