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1.
HDAC6 is a target for protection and regeneration following injury in the nervous system.
Proc Natl Acad Sci U S A
; 106(46): 19599-604, 2009 Nov 17.
Artículo
en Inglés
| MEDLINE | ID: mdl-19884510
2.
Selective inhibition of hypoxia-inducible factor (HIF) prolyl-hydroxylase 1 mediates neuroprotection against normoxic oxidative death via HIF- and CREB-independent pathways.
J Neurosci
; 29(27): 8828-38, 2009 Jul 08.
Artículo
en Inglés
| MEDLINE | ID: mdl-19587290
3.
Inhibition of prolyl hydroxylase protects against 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced neurotoxicity: model for the potential involvement of the hypoxia-inducible factor pathway in Parkinson disease.
J Biol Chem
; 284(42): 29065-76, 2009 Oct 16.
Artículo
en Inglés
| MEDLINE | ID: mdl-19679656
4.
Prolyl 4-hydroxylase activity-responsive transcription factors: from hydroxylation to gene expression and neuroprotection.
Front Biosci
; 13: 2875-87, 2008 Jan 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-17981760
5.
Harnessing hypoxic adaptation to prevent, treat, and repair stroke.
J Mol Med (Berl)
; 85(12): 1331-8, 2007 Dec.
Artículo
en Inglés
| MEDLINE | ID: mdl-18043901
6.
Antihelminthic benzimidazoles are novel HIF activators that prevent oxidative neuronal death via binding to tubulin.
Antioxid Redox Signal
; 22(2): 121-34, 2015 Jan 10.
Artículo
en Inglés
| MEDLINE | ID: mdl-24766300
7.
Translation of ischemic preconditioning to the patient: prolyl hydroxylase inhibition and hypoxia inducible factor-1 as novel targets for stroke therapy.
Stroke
; 35(11 Suppl 1): 2687-9, 2004 Nov.
Artículo
en Inglés
| MEDLINE | ID: mdl-15472113
8.
Antioxidants, HIF prolyl hydroxylase inhibitors or short interfering RNAs to BNIP3 or PUMA, can prevent prodeath effects of the transcriptional activator, HIF-1alpha, in a mouse hippocampal neuronal line.
Antioxid Redox Signal
; 10(12): 1989-98, 2008 Dec.
Artículo
en Inglés
| MEDLINE | ID: mdl-18774900
9.
Small molecule activation of adaptive gene expression: tilorone or its analogs are novel potent activators of hypoxia inducible factor-1 that provide prophylaxis against stroke and spinal cord injury.
Ann N Y Acad Sci
; 1147: 383-94, 2008 Dec.
Artículo
en Inglés
| MEDLINE | ID: mdl-19076458
10.
Hypoxia inducible factor prolyl 4-hydroxylase enzymes: center stage in the battle against hypoxia, metabolic compromise and oxidative stress.
Neurochem Res
; 32(4-5): 931-46, 2007.
Artículo
en Inglés
| MEDLINE | ID: mdl-17342411
11.
Proteasome inhibition protects HT22 neuronal cells from oxidative glutamate toxicity.
J Neurochem
; 92(4): 824-30, 2005 Feb.
Artículo
en Inglés
| MEDLINE | ID: mdl-15686484
12.
Hypoxia-inducible factor prolyl 4-hydroxylase inhibition. A target for neuroprotection in the central nervous system.
J Biol Chem
; 280(50): 41732-43, 2005 Dec 16.
Artículo
en Inglés
| MEDLINE | ID: mdl-16227210
13.
The c-Raf inhibitor GW5074 provides neuroprotection in vitro and in an animal model of neurodegeneration through a MEK-ERK and Akt-independent mechanism.
J Neurochem
; 90(3): 595-608, 2004 Aug.
Artículo
en Inglés
| MEDLINE | ID: mdl-15255937
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