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1.
Alkyl Amine Bevirimat Derivatives Are Potent and Broadly Active HIV-1 Maturation Inhibitors.
Antimicrob Agents Chemother
; 60(1): 190-7, 2016 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-26482309
2.
Molecular basis for failure of "atypical" C1 domain of Vav1 to bind diacylglycerol/phorbol ester.
J Biol Chem
; 287(16): 13137-58, 2012 Apr 13.
Artículo
en Inglés
| MEDLINE | ID: mdl-22351766
3.
N-methyl-substituted fluorescent DAG-indololactone isomers exhibit dramatic differences in membrane interactions and biological activity.
Chembiochem
; 12(15): 2331-40, 2011 Oct 17.
Artículo
en Inglés
| MEDLINE | ID: mdl-23106081
4.
Membrane-surface anchoring of charged diacylglycerol-lactones correlates with biological activities.
Chembiochem
; 11(14): 2003-9, 2010 Sep 24.
Artículo
en Inglés
| MEDLINE | ID: mdl-20715268
5.
Botryllamide G is an ABCG2 inhibitor that improves lapatinib delivery in mouse brain.
Cancer Biol Ther
; 21(3): 223-230, 2020.
Artículo
en Inglés
| MEDLINE | ID: mdl-31709896
6.
Ceramides: branched alkyl chains in the sphingolipid siblings of diacylglycerol improve biological potency.
Bioorg Med Chem
; 17(4): 1498-505, 2009 Feb 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-19171486
7.
Conformationally constrained analogues of diacylglycerol (DAG). 28. DAG-dioxolanones reveal a new additional interaction site in the C1b domain of PKC delta.
J Med Chem
; 50(15): 3465-81, 2007 Jul 26.
Artículo
en Inglés
| MEDLINE | ID: mdl-17591763
8.
Conformationally constrained analogues of diacylglycerol (DAG). 27. Modulation of membrane translocation of protein kinase C (PKC) isozymes alpha and delta by diacylglycerol lactones (DAG-lactones) containing rigid-rod acyl groups.
J Med Chem
; 50(5): 962-78, 2007 Mar 08.
Artículo
en Inglés
| MEDLINE | ID: mdl-17284021
9.
Infectious Entry and Neutralization of Pathogenic JC Polyomaviruses.
Cell Rep
; 21(5): 1169-1179, 2017 Oct 31.
Artículo
en Inglés
| MEDLINE | ID: mdl-29091757
10.
Conformationally constrained analogues of diacylglycerol. 26. Exploring the chemical space surrounding the C1 domain of protein kinase C with DAG-lactones containing aryl groups at the sn-1 and sn-2 positions.
J Med Chem
; 49(11): 3185-203, 2006 Jun 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-16722637
11.
Conformationally constrained analogues of diacylglycerol. 21. A solid-phase method of synthesis of diacylglycerol lactones as a prelude to a combinatorial approach for the synthesis of protein kinase C isozyme-specific ligands.
J Med Chem
; 47(12): 3248-54, 2004 Jun 03.
Artículo
en Inglés
| MEDLINE | ID: mdl-15163204
12.
Conformationally constrained analogues of diacylglycerol. 20. The search for an elusive binding site on protein kinase C through relocation of the carbonyl pharmacophore along the sn-1 side chain of 1,2-diacylglycerol lactones.
J Med Chem
; 47(3): 644-55, 2004 Jan 29.
Artículo
en Inglés
| MEDLINE | ID: mdl-14736244
13.
Conformationally constrained analogues of diacylglycerol (DAG). 23. Hydrophobic ligand-protein interactions versus ligand-lipid interactions of DAG-lactones with protein kinase C (PK-C).
J Med Chem
; 47(20): 4858-64, 2004 Sep 23.
Artículo
en Inglés
| MEDLINE | ID: mdl-15369389
14.
Differential binding modes of diacylglycerol (DAG) and DAG lactones to protein kinase C (PK-C).
J Med Chem
; 46(9): 1571-9, 2003 Apr 24.
Artículo
en Inglés
| MEDLINE | ID: mdl-12699375
15.
Conformationally constrained analogues of diacylglycerol. 24. Asymmetric synthesis of a chiral (R)-DAG-lactone template as a versatile precursor for highly functionalized DAG-lactones.
Org Lett
; 6(14): 2413-6, 2004 Jul 08.
Artículo
en Inglés
| MEDLINE | ID: mdl-15228292
16.
Diacylglycerol lactones targeting the structural features that distinguish the atypical C1 domains of protein kinase C ζ and ι from typical C1 domains.
J Med Chem
; 57(9): 3835-44, 2014 May 08.
Artículo
en Inglés
| MEDLINE | ID: mdl-24684293
17.
Carbeneminus signAlkyneminus signAlkene Cyclization Reactions.
Chem Rev
; 96(1): 271-288, 1996 Feb 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-11848753
18.
Materials from peptide assembly: towards the treatment of cancer and transmittable disease.
Curr Opin Chem Biol
; 15(3): 427-34, 2011 Jun.
Artículo
en Inglés
| MEDLINE | ID: mdl-21507707
19.
North- and south-bicyclo[3.1.0]hexene nucleosides: the effect of ring planarity on anti-HIV activity.
ChemMedChem
; 4(8): 1354-63, 2009 Aug.
Artículo
en Inglés
| MEDLINE | ID: mdl-19533724
20.
Conformationally constrained analogues of diacylglycerol. 29. Cells sort diacylglycerol-lactone chemical zip codes to produce diverse and selective biological activities.
J Med Chem
; 51(17): 5198-220, 2008 Sep 11.
Artículo
en Inglés
| MEDLINE | ID: mdl-18698758