Detalles de la búsqueda
1.
Further studies on the application of vinylogous amides and ß-halovinylaldehydes to the regiospecific synthesis of unsymmetrical, polyfunctionalized 2,3,4- and 1,2,3,4- substituted pyrroles.
Tetrahedron
; 74(21): 2650-2663, 2018 May 24.
Artículo
en Inglés
| MEDLINE | ID: mdl-30344350
2.
Application of vinylogous carbamates and vinylogous aminonitriles to the regiospecific synthesis of uniquely functionalized pyrroles and quinolones.
Tetrahedron
; 74(52): 7408-7420, 2018 Dec 27.
Artículo
en Inglés
| MEDLINE | ID: mdl-31289413
3.
Ortho group activation of a bromopyrrole ester in Suzuki-Miyaura cross-coupling reactions: Application to the synthesis of new microtubule depolymerizing agents with potent cytotoxic activities.
Bioorg Med Chem
; 25(12): 3206-3214, 2017 06 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-28433513
4.
Biological Characterization of an Improved Pyrrole-Based Colchicine Site Agent Identified through Structure-Based Design.
Mol Pharmacol
; 89(2): 287-96, 2016 Feb.
Artículo
en Inglés
| MEDLINE | ID: mdl-26655304
5.
The Application of Vinylogous Iminium Salt Derivatives and Microwave Accelerated Vilsmeier-Haack Reactions to Efficient Relay Syntheses of the Polycitone and Storniamide Natural Products.
Tetrahedron
; 64(22): 5246-5253, 2008.
Artículo
en Inglés
| MEDLINE | ID: mdl-18709182
6.
Carboxylated, heteroaryl-substituted chalcones as inhibitors of vascular cell adhesion molecule-1 expression for use in chronic inflammatory diseases.
J Med Chem
; 50(6): 1304-15, 2007 Mar 22.
Artículo
en Inglés
| MEDLINE | ID: mdl-17323940
7.
Discovery of novel phenolic antioxidants as inhibitors of vascular cell adhesion molecule-1 expression for use in chronic inflammatory diseases.
J Med Chem
; 47(25): 6420-32, 2004 Dec 02.
Artículo
en Inglés
| MEDLINE | ID: mdl-15566311
8.
Discovery of a simple picomolar inhibitor of cholesteryl ester transfer protein.
J Med Chem
; 46(11): 2152-68, 2003 May 22.
Artículo
en Inglés
| MEDLINE | ID: mdl-12747787
9.
Chiral N,N-disubstituted trifluoro-3-amino-2-propanols are potent inhibitors of cholesteryl ester transfer protein.
J Med Chem
; 45(18): 3891-904, 2002 Aug 29.
Artículo
en Inglés
| MEDLINE | ID: mdl-12190312
10.
Bio-active engineered 50 nm silica nanoparticles with bone anabolic activity: therapeutic index, effective concentration, and cytotoxicity profile in vitro.
Toxicol In Vitro
; 28(3): 354-64, 2014 Apr.
Artículo
en Inglés
| MEDLINE | ID: mdl-24333519
11.
Oral cholesteryl ester transfer protein (CETP) inhibitors: a potential new approach for treating coronary artery disease.
J Med Chem
; 49(1): 1-22, 2006 Jan 12.
Artículo
en Inglés
| MEDLINE | ID: mdl-16392785
12.
AGIX-4207 [2-[4-[[1-[[3,5-bis(1,1-dimethylethyl)-4-hydroxyphenyl]thio]-1-methylethyl]thio]-2,6-bis(1,1-dimethylethyl)phenoxy]acetic acid], a novel antioxidant and anti-inflammatory compound: cellular and biochemical characterization of antioxidant activity and inhibition of redox-sensitive inflammatory gene expression.
J Pharmacol Exp Ther
; 313(2): 492-501, 2005 May.
Artículo
en Inglés
| MEDLINE | ID: mdl-15701708
13.
N-myristoylation of Arf proteins in Candida albicans: an in vivo assay for evaluating antifungal inhibitors of myristoyl-CoA: protein N-myristoyltransferase.
Microbiology (Reading)
; 143 ( Pt 2): 357-366, 1997 Feb.
Artículo
en Inglés
| MEDLINE | ID: mdl-9043113
14.
Discovery of novel benzothiazolesulfonamides as potent inhibitors of HIV-1 protease.
Bioorg Med Chem
; 11(22): 4769-77, 2003 Nov 03.
Artículo
en Inglés
| MEDLINE | ID: mdl-14556792
15.
Discovery of novel heteroaryl-substituted chalcones as inhibitors of TNF-alpha-induced VCAM-1 expression.
Bioorg Med Chem Lett
; 14(6): 1513-7, 2004 Mar 22.
Artículo
en Inglés
| MEDLINE | ID: mdl-15006393
16.
Novel phenolic antioxidants as multifunctional inhibitors of inducible VCAM-1 expression for use in atherosclerosis.
Bioorg Med Chem Lett
; 12(18): 2545-8, 2002 Sep 16.
Artículo
en Inglés
| MEDLINE | ID: mdl-12182856
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