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1.
Commentary: Value of information case study strongly supports use of the Threshold of Toxicological Concern (TTC).
Regul Toxicol Pharmacol
; 149: 105594, 2024 May.
Artículo
en Inglés
| MEDLINE | ID: mdl-38555099
2.
Species differences in specific ligand-binding affinity and activation of AHR: The biological basis for calculation of relative effective potencies and toxic equivalence factors.
Regul Toxicol Pharmacol
; 149: 105598, 2024 May.
Artículo
en Inglés
| MEDLINE | ID: mdl-38548044
3.
Letter to the Editor: Modeling the changing face of Phosphatidylethanol's window of detection.
Regul Toxicol Pharmacol
; 146: 105537, 2024 Jan.
Artículo
en Inglés
| MEDLINE | ID: mdl-38052393
4.
The 2022 revised WHO TEFs for dioxins and dioxin-like chemicals: The importance of considering the use of species-specific information to determine relative effective potency for human-based risk assessment.
Regul Toxicol Pharmacol
; 149: 105599, 2024 May.
Artículo
en Inglés
| MEDLINE | ID: mdl-38490576
5.
Providing context for phosphatidylethanol as a biomarker of alcohol consumption with a pharmacokinetic model.
Regul Toxicol Pharmacol
; 94: 163-171, 2018 Apr.
Artículo
en Inglés
| MEDLINE | ID: mdl-29408287
6.
How well can carcinogenicity be predicted by high throughput "characteristics of carcinogens" mechanistic data?
Regul Toxicol Pharmacol
; 90: 185-196, 2017 Nov.
Artículo
en Inglés
| MEDLINE | ID: mdl-28866267
7.
Bayesian methods for uncertainty factor application for derivation of reference values.
Regul Toxicol Pharmacol
; 80: 9-24, 2016 Oct.
Artículo
en Inglés
| MEDLINE | ID: mdl-27211295
8.
The adverse outcome pathway for rodent liver tumor promotion by sustained activation of the aryl hydrocarbon receptor.
Regul Toxicol Pharmacol
; 73(1): 172-90, 2015 Oct.
Artículo
en Inglés
| MEDLINE | ID: mdl-26145830
9.
An exposure:activity profiling method for interpreting high-throughput screening data for estrogenic activity--proof of concept.
Regul Toxicol Pharmacol
; 71(3): 398-408, 2015 Apr.
Artículo
en Inglés
| MEDLINE | ID: mdl-25656492
10.
Proposing a scientific confidence framework to help support the application of adverse outcome pathways for regulatory purposes.
Regul Toxicol Pharmacol
; 71(3): 463-77, 2015 Apr.
Artículo
en Inglés
| MEDLINE | ID: mdl-25707856
11.
The use of mode of action information in risk assessment: quantitative key events/dose-response framework for modeling the dose-response for key events.
Crit Rev Toxicol
; 44 Suppl 3: 17-43, 2014 Aug.
Artículo
en Inglés
| MEDLINE | ID: mdl-25070415
12.
Utilizing Threshold of Toxicological Concern (TTC) with High Throughput Exposure Predictions (HTE) as a Risk-Based Prioritization Approach for thousands of chemicals.
Comput Toxicol
; 7: 58-67, 2018.
Artículo
en Inglés
| MEDLINE | ID: mdl-31338483
13.
In vitro to in vivo extrapolation for high throughput prioritization and decision making.
Toxicol In Vitro
; 47: 213-227, 2018 Mar.
Artículo
en Inglés
| MEDLINE | ID: mdl-29203341
14.
A model for aryl hydrocarbon receptor-activated gene expression shows potency and efficacy changes and predicts squelching due to competition for transcription co-activators.
PLoS One
; 10(6): e0127952, 2015.
Artículo
en Inglés
| MEDLINE | ID: mdl-26039703
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