Detalles de la búsqueda
1.
Targeting Mycobacterium tuberculosis: Synthesis, in vitro and in silico evaluation of novel N1 -(benzo[d]oxazol-2-yl)-N4 -arylidine compounds.
Arch Pharm (Weinheim)
; 356(8): e2300187, 2023 Aug.
Artículo
en Inglés
| MEDLINE | ID: mdl-37279375
2.
Synthesis, computational study and biological evaluation of 9-acridinyl and 1-coumarinyl-1,2,3-triazole-4-yl derivatives as topoisomerase II inhibitors.
J Enzyme Inhib Med Chem
; 37(1): 502-513, 2022 Dec.
Artículo
en Inglés
| MEDLINE | ID: mdl-35012398
3.
Long-term health outcomes of people with reduced kidney function in the UK: A modelling study using population health data.
PLoS Med
; 17(12): e1003478, 2020 12.
Artículo
en Inglés
| MEDLINE | ID: mdl-33326459
4.
Molecular Insights into Human Transmembrane Protease Serine-2 (TMPS2) Inhibitors against SARS-CoV2: Homology Modelling, Molecular Dynamics, and Docking Studies.
Molecules
; 25(21)2020 Oct 29.
Artículo
en Inglés
| MEDLINE | ID: mdl-33137894
5.
Understanding cornea homeostasis and wound healing using a novel model of stem cell deficiency in Xenopus.
Exp Eye Res
; 187: 107767, 2019 10.
Artículo
en Inglés
| MEDLINE | ID: mdl-31437439
6.
Synthesis and anti-HSV activity of tricyclic penciclovir and hydroxybutylguanine derivatives.
Bioorg Med Chem
; 27(6): 1023-1033, 2019 03 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-30738653
7.
Synthesis and biological evaluation of novel cYY analogues targeting Mycobacterium tuberculosis CYP121A1.
Bioorg Med Chem
; 27(8): 1546-1561, 2019 04 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-30837169
8.
Design, synthesis and evaluation against Mycobacterium tuberculosis of azole piperazine derivatives as dicyclotyrosine (cYY) mimics.
Bioorg Med Chem
; 26(1): 161-176, 2018 01 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-29183661
9.
Design, Synthesis and Microbiological Evaluation of Novel Compounds as Potential Staphylococcus aureus Phenylalanine tRNA Synthetase Inhibitors.
Egypt J Chem
; 61(Conference Iss): 9-25, 2018.
Artículo
en Inglés
| MEDLINE | ID: mdl-31937997
10.
Analysis of the binding sites of vitamin D 1α-hydroxylase (CYP27B1) and vitamin D 24-hydroxylase (CYP24A1) for the design of selective CYP24A1 inhibitors: Homology modelling, molecular dynamics simulations and identification of key binding requirements.
Bioorg Med Chem
; 25(20): 5629-5636, 2017 10 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-28886997
11.
Synthesis, molecular modelling and CYP24A1 inhibitory activity of novel of (E)-N-(2-(1H-imidazol-1-yl)-2-(phenylethyl)-3/4-styrylbenzamides.
Bioorg Med Chem
; 25(15): 4076-4087, 2017 08 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-28601511
12.
Targeting methionyl tRNA synthetase: design, synthesis and antibacterial activity against Clostridium difficile of novel 3-biaryl-N-benzylpropan-1-amine derivatives.
J Enzyme Inhib Med Chem
; 31(6): 1694-7, 2016 Dec.
Artículo
en Inglés
| MEDLINE | ID: mdl-26899668
13.
Multiple imputation to deal with missing EQ-5D-3L data: Should we impute individual domains or the actual index?
Qual Life Res
; 24(4): 805-15, 2015 Apr.
Artículo
en Inglés
| MEDLINE | ID: mdl-25471286
14.
The natural productome.
Proc Natl Acad Sci U S A
; 114(22): 5564-5566, 2017 05 30.
Artículo
en Inglés
| MEDLINE | ID: mdl-28533417
15.
Exploring Proteus mirabilis Methionine tRNA Synthetase Active Site: Homology Model Construction, Molecular Dynamics, Pharmacophore and Docking Validation.
Pharmaceuticals (Basel)
; 16(9)2023 Sep 06.
Artículo
en Inglés
| MEDLINE | ID: mdl-37765071
16.
Pyridine based dual binding site aromatase (CYP19A1) inhibitors.
RSC Med Chem
; 14(2): 356-366, 2023 Feb 22.
Artículo
en Inglés
| MEDLINE | ID: mdl-36846364
17.
Long-Term Outcomes of Eladocagene Exuparvovec Compared with Standard of Care in Aromatic L-Amino Acid Decarboxylase (AADC) Deficiency: A Modelling Study.
Adv Ther
; 40(12): 5399-5414, 2023 12.
Artículo
en Inglés
| MEDLINE | ID: mdl-37803205
18.
Use of hydrogen peroxide as a biocide: new consideration of its mechanisms of biocidal action.
J Antimicrob Chemother
; 67(7): 1589-96, 2012 Jul.
Artículo
en Inglés
| MEDLINE | ID: mdl-22532463
19.
Novel retinoic acid 4-hydroxylase (CYP26) inhibitors based on a 3-(1H-imidazol- and triazol-1-yl)-2,2-dimethyl-3-(4-(phenylamino)phenyl)propyl scaffold.
Bioorg Med Chem
; 20(14): 4201-7, 2012 Jul 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-22727372
20.
Synthesis and CYP26A1 inhibitory activity of novel methyl 3-[4-(arylamino)phenyl]-3-(azole)-2,2-dimethylpropanoates.
Bioorg Med Chem
; 20(20): 6080-8, 2012 Oct 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-22989911