Detalles de la búsqueda
1.
Lipophilic Statins Inhibit YAP Nuclear Localization, Coactivator Activity, and Migration in Response to Ligation of HLA Class I Molecules in Endothelial Cells: Role of YAP Multisite Phosphorylation.
J Immunol
; 210(8): 1134-1145, 2023 04 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-36881871
2.
Statins inhibit protein kinase D (PKD) activation in intestinal cells and prevent PKD1-induced growth of murine enteroids.
Am J Physiol Cell Physiol
; 324(4): C807-C820, 2023 04 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-36779664
3.
Lipophilic statins inhibit YAP coactivator transcriptional activity in HCC cells through Rho-mediated modulation of actin cytoskeleton.
Am J Physiol Gastrointest Liver Physiol
; 325(3): G239-G250, 2023 09 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-37366601
4.
Ligation of HLA Class I Molecules Induces YAP Activation through Src in Human Endothelial Cells.
J Immunol
; 205(7): 1953-1961, 2020 10 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-32848033
5.
Protein kinase D1 (PKD1) phosphorylation on Ser203 by type I p21-activated kinase (PAK) regulates PKD1 localization.
J Biol Chem
; 292(23): 9523-9539, 2017 06 09.
Artículo
en Inglés
| MEDLINE | ID: mdl-28408623
6.
Deficiency in hormone-sensitive lipase accelerates the development of pancreatic cancer in conditional KrasG12D mice.
BMC Cancer
; 18(1): 797, 2018 Aug 07.
Artículo
en Inglés
| MEDLINE | ID: mdl-30086728
7.
Biphasic Regulation of Yes-associated Protein (YAP) Cellular Localization, Phosphorylation, and Activity by G Protein-coupled Receptor Agonists in Intestinal Epithelial Cells: A NOVEL ROLE FOR PROTEIN KINASE D (PKD).
J Biol Chem
; 291(34): 17988-8005, 2016 08 19.
Artículo
en Inglés
| MEDLINE | ID: mdl-27369082
8.
Positive cross talk between protein kinase D and ß-catenin in intestinal epithelial cells: impact on ß-catenin nuclear localization and phosphorylation at Ser552.
Am J Physiol Cell Physiol
; 310(7): C542-57, 2016 Apr 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-26739494
9.
Prostaglandin E2 activates the mTORC1 pathway through an EP4/cAMP/PKA- and EP1/Ca2+-mediated mechanism in the human pancreatic carcinoma cell line PANC-1.
Am J Physiol Cell Physiol
; 309(10): C639-49, 2015 Nov 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-26310818
10.
Intracellular Ca2+ oscillations generated via the Ca2+-sensing receptor are mediated by negative feedback by PKCα at Thr888.
Am J Physiol Cell Physiol
; 306(3): C298-306, 2014 Feb 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-24336654
11.
Protein kinase D1 mediates class IIa histone deacetylase phosphorylation and nuclear extrusion in intestinal epithelial cells: role in mitogenic signaling.
Am J Physiol Cell Physiol
; 306(10): C961-71, 2014 May 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-24647541
12.
Metformin inhibition of mTORC1 activation, DNA synthesis and proliferation in pancreatic cancer cells: dependence on glucose concentration and role of AMPK.
Biochem Biophys Res Commun
; 430(1): 352-7, 2013 Jan 04.
Artículo
en Inglés
| MEDLINE | ID: mdl-23159620
13.
TNF-α and LPA promote synergistic expression of COX-2 in human colonic myofibroblasts: role of LPA-mediated transactivation of upregulated EGFR.
BMC Gastroenterol
; 13: 90, 2013 May 20.
Artículo
en Inglés
| MEDLINE | ID: mdl-23688423
14.
Low dosage combination treatment with metformin and simvastatin inhibits obesity-promoted pancreatic cancer development in male KrasG12D mice.
Sci Rep
; 13(1): 16144, 2023 09 26.
Artículo
en Inglés
| MEDLINE | ID: mdl-37752238
15.
Protein kinase D1 mediates stimulation of DNA synthesis and proliferation in intestinal epithelial IEC-18 cells and in mouse intestinal crypts.
J Biol Chem
; 286(1): 511-20, 2011 Jan 07.
Artículo
en Inglés
| MEDLINE | ID: mdl-21051537
16.
Rapid protein kinase D1 signaling promotes migration of intestinal epithelial cells.
Am J Physiol Gastrointest Liver Physiol
; 303(3): G356-66, 2012 Aug 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-22595992
17.
TNF-α induces upregulation of EGFR expression and signaling in human colonic myofibroblasts.
Am J Physiol Gastrointest Liver Physiol
; 302(8): G805-14, 2012 Apr 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-22301110
18.
Opposite Effects of Src Family Kinases on YAP and ERK Activation in Pancreatic Cancer Cells: Implications for Targeted Therapy.
Mol Cancer Ther
; 21(11): 1652-1662, 2022 11 03.
Artículo
en Inglés
| MEDLINE | ID: mdl-35999654
19.
Statins Inhibit Inflammatory Cytokine Production by Macrophages and Acinar-to-Ductal Metaplasia of Pancreatic Cells.
Gastro Hep Adv
; 1(4): 640-651, 2022.
Artículo
en Inglés
| MEDLINE | ID: mdl-36313271
20.
Protein kinase D1 promotes anchorage-independent growth, invasion, and angiogenesis by human pancreatic cancer cells.
J Cell Physiol
; 226(4): 1074-81, 2011 Apr.
Artículo
en Inglés
| MEDLINE | ID: mdl-20857418