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1.
Target guided synthesis of 5-benzyl-2,4-diamonopyrimidines: their antimalarial activities and binding affinities to wild type and mutant dihydrofolate reductases from Plasmodium falciparum.
J Med Chem
; 47(2): 345-54, 2004 Jan 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-14711307
2.
Development of 2,4-diaminopyrimidines as antimalarials based on inhibition of the S108N and C59R+S108N mutants of dihydrofolate reductase from pyrimethamine-resistant Plasmodium falciparum.
J Med Chem
; 45(6): 1244-52, 2002 Mar 14.
Artículo
en Inglés
| MEDLINE | ID: mdl-11881993
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