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1.
Prediction of liver volume - a population-based approach to meta-analysis of paediatric, adult and geriatric populations - an update.
Biopharm Drug Dispos
; 38(4): 290-300, 2017 May.
Artículo
en Inglés
| MEDLINE | ID: mdl-28084034
2.
Early assessment of proarrhythmic risk of drugs using the in vitro data and single-cell-based in silico models: proof of concept.
Toxicol Mech Methods
; 27(2): 88-99, 2017 Feb.
Artículo
en Inglés
| MEDLINE | ID: mdl-27813448
3.
Efficient discovery of anti-inflammatory small-molecule combinations using evolutionary computing.
Nat Chem Biol
; 7(12): 902-8, 2011 Oct 23.
Artículo
en Inglés
| MEDLINE | ID: mdl-22020553
4.
Another Step Toward Qualification of Pediatric Physiologically Based Pharmacokinetic Models to Facilitate Inclusivity and Diversity in Pediatric Clinical Studies.
Clin Pharmacol Ther
; 113(3): 735-745, 2023 03.
Artículo
en Inglés
| MEDLINE | ID: mdl-36306419
5.
Physiologically Based Pharmacokinetic Modelling to Predict Imatinib Exposures in Cancer Patients with Renal Dysfunction: A Case Study.
Pharmaceutics
; 15(7)2023 Jul 11.
Artículo
en Inglés
| MEDLINE | ID: mdl-37514108
6.
Incorporation and Performance Verification of Hepatic Portal Blood Flow Shunting in Minimal and Full PBPK Models of Liver Cirrhosis.
Clin Pharmacol Ther
; 114(6): 1264-1273, 2023 12.
Artículo
en Inglés
| MEDLINE | ID: mdl-37620290
7.
Development and application of a pediatric mechanistic kidney model.
CPT Pharmacometrics Syst Pharmacol
; 11(7): 854-866, 2022 07.
Artículo
en Inglés
| MEDLINE | ID: mdl-35506351
8.
Increasing application of pediatric physiologically based pharmacokinetic models across academic and industry organizations.
CPT Pharmacometrics Syst Pharmacol
; 11(3): 373-383, 2022 03.
Artículo
en Inglés
| MEDLINE | ID: mdl-35174656
9.
A best practice framework for applying physiologically-based pharmacokinetic modeling to pediatric drug development.
CPT Pharmacometrics Syst Pharmacol
; 10(9): 967-972, 2021 09.
Artículo
en Inglés
| MEDLINE | ID: mdl-34288581
10.
Integration of Omics Data Sources to Inform Mechanistic Modeling of Immune-Oncology Therapies: A Tutorial for Clinical Pharmacologists.
Clin Pharmacol Ther
; 107(4): 858-870, 2020 04.
Artículo
en Inglés
| MEDLINE | ID: mdl-31955413
11.
Gender differences in the slow delayed (IKs) but not in inward (IK1) rectifier K+ currents of canine Purkinje fibre cardiac action potential: key roles for IKs, beta-adrenoceptor stimulation, pacing rate and gender.
Br J Pharmacol
; 147(6): 653-60, 2006 Mar.
Artículo
en Inglés
| MEDLINE | ID: mdl-16314855
12.
Evidence for gender differences in electrophysiological properties of canine Purkinje fibres.
Br J Pharmacol
; 142(8): 1255-64, 2004 Aug.
Artículo
en Inglés
| MEDLINE | ID: mdl-15265803
13.
A Quantitative Systems Pharmacology Consortium Approach to Managing Immunogenicity of Therapeutic Proteins.
CPT Pharmacometrics Syst Pharmacol
; 8(11): 773-776, 2019 11.
Artículo
en Inglés
| MEDLINE | ID: mdl-31529677
14.
Validation of a voltage-sensitive dye (di-4-ANEPPS)-based method for assessing drug-induced delayed repolarisation in beagle dog left ventricular midmyocardial myocytes.
J Pharmacol Toxicol Methods
; 60(1): 94-106, 2009.
Artículo
en Inglés
| MEDLINE | ID: mdl-19414070
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