Detalles de la búsqueda
1.
Reaction Phenotyping of Low-Turnover Compounds in Long-Term Hepatocyte Cultures Through Persistent Selective Inhibition of Cytochromes P450.
Drug Metab Dispos
; 49(11): 995-1002, 2021 11.
Artículo
en Inglés
| MEDLINE | ID: mdl-34407991
2.
In vitro and in vivo characterisation of the metabolism and disposition of suvorexant in humans.
Xenobiotica
; 46(10): 882-95, 2016 Oct.
Artículo
en Inglés
| MEDLINE | ID: mdl-26864332
3.
Neonatal abstinence syndrome: evaluating the effectiveness of an evidence-based multidisciplinary care approach.
J Perinat Neonatal Nurs
; 28(3): 232-40, 2014.
Artículo
en Inglés
| MEDLINE | ID: mdl-25062525
4.
Phase I Study of Elraglusib (9-ING-41), a Glycogen Synthase Kinase-3ß Inhibitor, as Monotherapy or Combined with Chemotherapy in Patients with Advanced Malignancies.
Clin Cancer Res
; 30(3): 522-531, 2024 02 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-37982822
5.
Liquid extraction surface analysis mass spectrometry (LESA-MS) as a novel profiling tool for drug distribution and metabolism analysis: the terfenadine example.
Rapid Commun Mass Spectrom
; 25(23): 3587-96, 2011 Dec 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-22095508
6.
Establishment of a non-native xyleborine ambrosia beetle, Xyleborus monographus (Fabricius) (Coleoptera: Curculionidae: Scolytinae), new to North America in California.
Zootaxa
; 4786(2): zootaxa.4786.2.8, 2020 Jun 02.
Artículo
en Inglés
| MEDLINE | ID: mdl-33056488
7.
Discovery of N-{[1-(propylsulfonyl)-4-pyridin-2-ylpiperidin-4-yl]methyl}benzamides as novel, selective and potent GlyT1 inhibitors.
Bioorg Med Chem Lett
; 19(5): 1488-91, 2009 Mar 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-19179073
8.
Discovery of GlyT1 inhibitors with improved pharmacokinetic properties.
Bioorg Med Chem Lett
; 19(5): 1492-5, 2009 Mar 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-19181525
9.
Efficacy of Systemic Insecticides for Control of the Invasive Goldspotted Oak Borer (Coleoptera: Buprestidae) in California.
J Econ Entomol
; 110(5): 2129-2139, 2017 10 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-28981680
10.
Prediction of Metabolic Clearance for Low-Turnover Compounds Using Plated Hepatocytes with Enzyme Activity Correction.
Eur J Drug Metab Pharmacokinet
; 42(2): 319-326, 2017 Apr.
Artículo
en Inglés
| MEDLINE | ID: mdl-27101423
11.
Effectiveness of bifenthrin (Onyx) and carbaryl (Sevin SL) for protecting individual, high-value conifers from bark beetle attack (Coleoptera: Curculionidae: Scolytinae) in the Western United States.
J Econ Entomol
; 99(5): 1691-8, 2006 Oct.
Artículo
en Inglés
| MEDLINE | ID: mdl-17066800
12.
Effect of Contact Insecticides Against the Invasive Goldspotted Oak Borer (Coleoptera: Buprestidae) in California.
J Econ Entomol
; 109(6): 2436-2445, 2016 12.
Artículo
en Inglés
| MEDLINE | ID: mdl-27986940
13.
Phase I and pharmacokinetic study of irofulven administered weekly or biweekly in advanced solid tumor patients.
Clin Cancer Res
; 10(10): 3377-85, 2004 May 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-15161692
14.
Discovery of positive allosteric modulators for the metabotropic glutamate receptor subtype 5 from a series of N-(1,3-diphenyl-1H- pyrazol-5-yl)benzamides that potentiate receptor function in vivo.
J Med Chem
; 47(24): 5825-8, 2004 Nov 18.
Artículo
en Inglés
| MEDLINE | ID: mdl-15537338
15.
Development of a liver-targeted siRNA delivery platform with a broad therapeutic window utilizing biodegradable polypeptide-based polymer conjugates.
J Control Release
; 183: 124-37, 2014 Jun 10.
Artículo
en Inglés
| MEDLINE | ID: mdl-24657948
16.
Synthesis and SAR of GlyT1 inhibitors derived from a series of N-((4-(morpholine-4-carbonyl)-1-(propylsulfonyl)piperidin-4-yl)methyl)benzamides.
Bioorg Med Chem Lett
; 16(23): 5968-72, 2006 Dec 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-16987662
17.
Irofulven demonstrates clinical activity against metastatic hormone-refractory prostate cancer in a phase 2 single-agent trial.
Am J Clin Oncol
; 28(1): 36-42, 2005 Feb.
Artículo
en Inglés
| MEDLINE | ID: mdl-15685033
18.
A novel selective positive allosteric modulator of metabotropic glutamate receptor subtype 5 has in vivo activity and antipsychotic-like effects in rat behavioral models.
J Pharmacol Exp Ther
; 313(1): 199-206, 2005 Apr.
Artículo
en Inglés
| MEDLINE | ID: mdl-15608073
19.
Optimization of the indolyl quinolinone class of KDR (VEGFR-2) kinase inhibitors: effects of 5-amido- and 5-sulphonamido-indolyl groups on pharmacokinetics and hERG binding.
Bioorg Med Chem Lett
; 14(2): 351-5, 2004 Jan 19.
Artículo
en Inglés
| MEDLINE | ID: mdl-14698157
20.
Design, synthesis, and in vivo efficacy of glycine transporter-1 (GlyT1) inhibitors derived from a series of [4-phenyl-1-(propylsulfonyl)piperidin-4-yl]methyl benzamides.
ChemMedChem
; 1(8): 807-11, 2006 Aug.
Artículo
en Inglés
| MEDLINE | ID: mdl-16902933