Detalles de la búsqueda
1.
Safety and immunopharmacology of ASP0892 in adults or adolescents with peanut allergy: two randomized trials.
Allergy
; 79(2): 456-470, 2024 Feb.
Artículo
en Inglés
| MEDLINE | ID: mdl-38010254
2.
Distinct trajectories distinguish antigen-specific T cells in peanut-allergic individuals undergoing oral immunotherapy.
J Allergy Clin Immunol
; 152(1): 155-166.e9, 2023 07.
Artículo
en Inglés
| MEDLINE | ID: mdl-37003475
3.
Single- and multiple-dose safety, tolerability, pharmacokinetic, and pharmacodynamic profiles of ASP0367, or bocidelpar sulfate, a novel modulator of peroxisome proliferator-activated receptor delta in healthy adults: Results from a phase 1 study.
Muscle Nerve
; 65(1): 110-120, 2022 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-34642949
4.
Safety, tolerability and immunogenicity of a novel 24-valent pneumococcal vaccine in toddlers: A phase 1 randomized controlled trial.
Vaccine
; 42(10): 2560-2571, 2024 Apr 11.
Artículo
en Inglés
| MEDLINE | ID: mdl-38360475
5.
Phase 1/2 study of a novel 24-valent pneumococcal vaccine in healthy adults aged 18 to 64 years and in older adults aged 65 to 85 years.
Vaccine
; 40(31): 4190-4198, 2022 07 29.
Artículo
en Inglés
| MEDLINE | ID: mdl-35690500
6.
Strategies for the assessment of protein aggregates in pharmaceutical biotech product development.
Pharm Res
; 28(4): 920-33, 2011 Apr.
Artículo
en Inglés
| MEDLINE | ID: mdl-20972611
7.
ASP5094, a humanized monoclonal antibody against integrin alpha-9, did not show efficacy in patients with rheumatoid arthritis refractory to methotrexate: results from a phase 2a, randomized, double-blind, placebo-controlled trial.
Arthritis Res Ther
; 22(1): 252, 2020 10 21.
Artículo
en Inglés
| MEDLINE | ID: mdl-33087159
8.
NPT-IIb Inhibition Does Not Improve Hyperphosphatemia in CKD.
Kidney Int Rep
; 3(1): 73-80, 2018 Jan.
Artículo
en Inglés
| MEDLINE | ID: mdl-29340316
9.
Pharmacokinetic effect of ketoconazole on solifenacin in healthy volunteers.
Basic Clin Pharmacol Toxicol
; 99(1): 33-6, 2006 Jul.
Artículo
en Inglés
| MEDLINE | ID: mdl-16867168
10.
Pharmacokinetic interaction of solifenacin with an oral contraceptive containing ethinyl estradiol and levonorgestrel in healthy women: a double-blind, placebo-controlled study.
Clin Ther
; 27(9): 1403-10, 2005 Sep.
Artículo
en Inglés
| MEDLINE | ID: mdl-16291413
11.
Pharmacokinetics and safety of solifenacin succinate in healthy young men.
J Clin Pharmacol
; 44(9): 1023-33, 2004 Sep.
Artículo
en Inglés
| MEDLINE | ID: mdl-15317830
12.
Clinical pharmacokinetics and pharmacodynamics of the novel SGLT2 inhibitor ipragliflozin.
Clin Pharmacokinet
; 53(11): 975-88, 2014 Nov.
Artículo
en Inglés
| MEDLINE | ID: mdl-25316572
13.
Pharmacokinetic and pharmacodynamic study of ipragliflozin in Japanese patients with type 2 diabetes mellitus: a randomized, double-blind, placebo-controlled study.
Diabetes Res Clin Pract
; 106(1): 50-6, 2014 Oct.
Artículo
en Inglés
| MEDLINE | ID: mdl-25149596
14.
Renal glucose handling: impact of chronic kidney disease and sodium-glucose cotransporter 2 inhibition in patients with type 2 diabetes.
Diabetes Care
; 36(5): 1260-5, 2013 May.
Artículo
en Inglés
| MEDLINE | ID: mdl-23359360
15.
Ipragliflozin does not prolong QTc interval in healthy male and female subjects: a phase I study.
Clin Ther
; 35(8): 1150-1161.e3, 2013 Aug.
Artículo
en Inglés
| MEDLINE | ID: mdl-23910665
16.
The effect of moderate hepatic impairment on the pharmacokinetics of ipragliflozin, a novel sodium glucose co-transporter 2 (SGLT2) inhibitor.
Clin Drug Investig
; 33(7): 489-96, 2013 Jul.
Artículo
en Inglés
| MEDLINE | ID: mdl-23733389
17.
Combination treatment with ipragliflozin and metformin: a randomized, double-blind, placebo-controlled study in patients with type 2 diabetes mellitus.
Clin Ther
; 34(8): 1761-71, 2012 Aug.
Artículo
en Inglés
| MEDLINE | ID: mdl-22795925
18.
Effect of Ipragliflozin (ASP1941), a novel selective sodium-dependent glucose co-transporter 2 inhibitor, on urinary glucose excretion in healthy subjects.
Clin Drug Investig
; 31(12): 839-51, 2011 Dec 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-21877761
19.
Pharmacokinetics, safety, and tolerability of solifenacin in patients with renal insufficiency.
J Pharmacol Sci
; 103(1): 67-74, 2007 Jan.
Artículo
en Inglés
| MEDLINE | ID: mdl-17251687
20.
Open-label study of the safety and pharmacokinetics of solifenacin in subjects with hepatic impairment.
J Pharmacol Sci
; 102(4): 405-12, 2006 Dec.
Artículo
en Inglés
| MEDLINE | ID: mdl-17170513