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1.
Characterization of Antineovascularization Activity and Ocular Pharmacokinetics of Phosphoinositide 3-Kinase/Mammalian Target of Rapamycin Inhibitor GNE-947.
Drug Metab Dispos
; 48(5): 408-419, 2020 05.
Artículo
en Inglés
| MEDLINE | ID: mdl-32132091
2.
Pharmacokinetics and distribution of 2-hydroxypropyl-ß-cyclodextrin following a single intrathecal dose to cats.
J Inherit Metab Dis
; 43(3): 618-634, 2020 05.
Artículo
en Inglés
| MEDLINE | ID: mdl-31707730
3.
SCY-078, a Novel Fungicidal Agent, Demonstrates Distribution to Tissues Associated with Fungal Infections during Mass Balance Studies with Intravenous and Oral [14C]SCY-078 in Albino and Pigmented Rats.
Antimicrob Agents Chemother
; 63(2)2019 02.
Artículo
en Inglés
| MEDLINE | ID: mdl-30478166
4.
Pharmacokinetics, distribution, metabolism, and excretion of the dual reuptake inhibitor [(14)C]-nefopam in rats.
Xenobiotica
; 46(11): 1026-48, 2016 Nov.
Artículo
en Inglés
| MEDLINE | ID: mdl-26927982
5.
Autoradiography techniques and quantification of drug distribution.
Cell Tissue Res
; 360(1): 87-107, 2015 Apr.
Artículo
en Inglés
| MEDLINE | ID: mdl-25604842
6.
Peginesatide clearance, distribution, metabolism, and excretion in monkeys following intravenous administration.
Drug Metab Dispos
; 41(4): 774-84, 2013 Apr.
Artículo
en Inglés
| MEDLINE | ID: mdl-23318685
7.
Evaluation of metabolism and disposition of GDC-0152 in rats using 14C labeling strategy at two different positions: a novel formation of hippuric acid from 4-phenyl-5-amino-1,2,3-thiadiazole.
Drug Metab Dispos
; 41(2): 508-17, 2013 Feb.
Artículo
en Inglés
| MEDLINE | ID: mdl-23223496
8.
Use of radioactive compounds and autoradiography to determine drug tissue distribution.
Chem Res Toxicol
; 25(3): 543-55, 2012 Mar 19.
Artículo
en Inglés
| MEDLINE | ID: mdl-22280496
9.
Imaging Mass Spectrometry (IMS) for drug discovery and development survey: Results on methods, applications and regulatory compliance.
Drug Metab Pharmacokinet
; 43: 100438, 2022 Apr.
Artículo
en Inglés
| MEDLINE | ID: mdl-35091331
10.
Absorption, distribution, metabolism, and excretion of [¹4C]GDC-0449 (vismodegib), an orally active hedgehog pathway inhibitor, in rats and dogs: a unique metabolic pathway via pyridine ring opening.
Drug Metab Dispos
; 39(6): 952-65, 2011 Jun.
Artículo
en Inglés
| MEDLINE | ID: mdl-21363998
11.
Skin distribution of imidacloprid by microautoradiography after topical administration to beagle dogs.
Vet Ther
; 11(4): E1-10, 2010.
Artículo
en Inglés
| MEDLINE | ID: mdl-21308663
12.
Role of P-glycoprotein and the intestine in the excretion of DPC 333 [(2R)-2-{(3R)-3-amino-3-[4-(2-methylquinolin-4-ylmethoxy)phenyl]-2-oxopyrrolidin-1-yl}-N-hydroxy-4-methylpentanamide] in rodents.
Drug Metab Dispos
; 36(6): 1102-10, 2008 Jun.
Artículo
en Inglés
| MEDLINE | ID: mdl-18347085
13.
Enhancing the antiviral potency of ER α-glucosidase inhibitor IHVR-19029 against hemorrhagic fever viruses in vitro and in vivo.
Antiviral Res
; 150: 112-122, 2018 02.
Artículo
en Inglés
| MEDLINE | ID: mdl-29253498
14.
Increased hepatobiliary clearance of unconjugated thyroxine determines DMP 904-induced alterations in thyroid hormone homeostasis in rats.
Toxicol Sci
; 84(2): 232-42, 2005 Apr.
Artículo
en Inglés
| MEDLINE | ID: mdl-15673846
15.
Radiation dose to abdominal organs of the mouse due to 90Y in the urinary bladder.
Cancer Biother Radiopharm
; 18(3): 413-9, 2003 Jun.
Artículo
en Inglés
| MEDLINE | ID: mdl-12954127
16.
Autoradiography, MALDI-MS, and SIMS-MS imaging in pharmaceutical discovery and development.
AAPS J
; 12(1): 11-26, 2010 Mar.
Artículo
en Inglés
| MEDLINE | ID: mdl-19921438
17.
Autoradiography: high-resolution molecular imaging in pharmaceutical discovery and development.
Expert Opin Drug Discov
; 2(4): 503-14, 2007 Apr.
Artículo
en Inglés
| MEDLINE | ID: mdl-23484758
18.
Distribution of radioactivity in bone and related structures following administration of [14C]dalbavancin to New Zealand white rabbits.
Antimicrob Agents Chemother
; 51(8): 3008-10, 2007 Aug.
Artículo
en Inglés
| MEDLINE | ID: mdl-17548492
19.
Interaction of ritonavir on tissue distribution of a [(14)c]L-valinamide, a potent human immunodeficiency virus-1 protease inhibitor, in rats using quantitative whole-body autoradiography.
Drug Metab Dispos
; 30(11): 1164-9, 2002 Nov.
Artículo
en Inglés
| MEDLINE | ID: mdl-12386120
20.
Concurrent induction and mechanism-based inactivation of CYP3A4 by an L-valinamide derivative.
Drug Metab Dispos
; 31(9): 1170-5, 2003 Sep.
Artículo
en Inglés
| MEDLINE | ID: mdl-12920173
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