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1.
The architecture of hydrogen and sulfur σ-hole interactions explain differences in the inhibitory potency of C-ß-d-glucopyranosyl thiazoles, imidazoles and an N-ß-d glucopyranosyl tetrazole for human liver glycogen phosphorylase and offer new insights to structure-based design.
Bioorg Med Chem
; 28(1): 115196, 2020 01 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-31767404
2.
Probing the ß-pocket of the active site of human liver glycogen phosphorylase with 3-(C-ß-d-glucopyranosyl)-5-(4-substituted-phenyl)-1, 2, 4-triazole inhibitors.
Bioorg Chem
; 77: 485-493, 2018 04.
Artículo
en Inglés
| MEDLINE | ID: mdl-29454281
3.
van der Waals interactions govern C-ß-d-glucopyranosyl triazoles' nM inhibitory potency in human liver glycogen phosphorylase.
J Struct Biol
; 199(1): 57-67, 2017 07.
Artículo
en Inglés
| MEDLINE | ID: mdl-28483603
4.
Biochemical and Structural Studies of LjSK1, a Lotus japonicus GSK3ß/SHAGGY-like Kinase, Reveal Its Functional Role.
J Agric Food Chem
; 72(7): 3763-3772, 2024 Feb 21.
Artículo
en Inglés
| MEDLINE | ID: mdl-38330914
5.
Novel diarylamides and diarylureas with N-substitution dependent activity against medulloblastoma.
Eur J Med Chem
; 225: 113751, 2021 Dec 05.
Artículo
en Inglés
| MEDLINE | ID: mdl-34391032
6.
Mutagenesis of a Lotus japonicus GSK3ß/Shaggy-like kinase reveals functionally conserved regulatory residues.
Phytochemistry
; 186: 112707, 2021 Jun.
Artículo
en Inglés
| MEDLINE | ID: mdl-33721796
7.
Affinity Crystallography Reveals the Bioactive Compounds of Industrial Juicing Byproducts of Punica granatum for Glycogen Phosphorylase.
Curr Drug Discov Technol
; 15(1): 41-53, 2018.
Artículo
en Inglés
| MEDLINE | ID: mdl-28625148
8.
Nanomolar Inhibitors of Glycogen Phosphorylase Based on ß-d-Glucosaminyl Heterocycles: A Combined Synthetic, Enzyme Kinetic, and Protein Crystallography Study.
J Med Chem
; 60(22): 9251-9262, 2017 11 22.
Artículo
en Inglés
| MEDLINE | ID: mdl-28925695
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