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1.
Strong suppression of gene conversion with increasing DNA double-strand break load delimited by 53BP1 and RAD52.
Nucleic Acids Res
; 48(4): 1905-1924, 2020 02 28.
Artículo
en Inglés
| MEDLINE | ID: mdl-31832684
2.
ATR Contributes More Than ATM in Intra-S-Phase Checkpoint Activation after IR, and DNA-PKcs Facilitates Recovery: Evidence for Modular Integration of ATM/ATR/DNA-PKcs Functions.
Int J Mol Sci
; 23(14)2022 Jul 06.
Artículo
en Inglés
| MEDLINE | ID: mdl-35886852
3.
PTEN Loss Enhances Error-Prone DSB Processing and Tumor Cell Radiosensitivity by Suppressing RAD51 Expression and Homologous Recombination.
Int J Mol Sci
; 23(21)2022 Oct 25.
Artículo
en Inglés
| MEDLINE | ID: mdl-36361678
4.
Disruption of Chromatin Dynamics by Hypotonic Stress Suppresses HR and Shifts DSB Processing to Error-Prone SSA.
Int J Mol Sci
; 22(20)2021 Oct 11.
Artículo
en Inglés
| MEDLINE | ID: mdl-34681628
5.
Chromosome thripsis by DNA double strand break clusters causes enhanced cell lethality, chromosomal translocations and 53BP1-recruitment.
Nucleic Acids Res
; 44(16): 7673-90, 2016 09 19.
Artículo
en Inglés
| MEDLINE | ID: mdl-27257076
6.
DNA double-strand-break repair in higher eukaryotes and its role in genomic instability and cancer: Cell cycle and proliferation-dependent regulation.
Semin Cancer Biol
; 37-38: 51-64, 2016 06.
Artículo
en Inglés
| MEDLINE | ID: mdl-27016036
7.
Requirement for Parp-1 and DNA ligases 1 or 3 but not of Xrcc1 in chromosomal translocation formation by backup end joining.
Nucleic Acids Res
; 42(10): 6380-92, 2014 Jun.
Artículo
en Inglés
| MEDLINE | ID: mdl-24748665
8.
The p38/MK2 Pathway Functions as Chk1-Backup Downstream of ATM/ATR in G2-Checkpoint Activation in Cells Exposed to Ionizing Radiation.
Cells
; 12(10)2023 05 14.
Artículo
en Inglés
| MEDLINE | ID: mdl-37408221
9.
Low CDK Activity and Enhanced Degradation by APC/CCDH1 Abolishes CtIP Activity and Alt-EJ in Quiescent Cells.
Cells
; 12(11)2023 06 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-37296650
10.
BMN673 Is a PARP Inhibitor with Unique Radiosensitizing Properties: Mechanisms and Potential in Radiation Therapy.
Cancers (Basel)
; 14(22)2022 Nov 16.
Artículo
en Inglés
| MEDLINE | ID: mdl-36428712
11.
Increased Resection at DSBs in G2-Phase Is a Unique Phenotype Associated with DNA-PKcs Defects That Is Not Shared by Other Factors of c-NHEJ.
Cells
; 11(13)2022 07 02.
Artículo
en Inglés
| MEDLINE | ID: mdl-35805183
12.
Proficiency in homologous recombination repair is prerequisite for activation of G2-checkpoint at low radiation doses.
DNA Repair (Amst)
; 101: 103076, 2021 05.
Artículo
en Inglés
| MEDLINE | ID: mdl-33640756
13.
Analysis of chromatid-break-repair detects a homologous recombination to non-homologous end-joining switch with increasing load of DNA double-strand breaks.
Mutat Res Genet Toxicol Environ Mutagen
; 867: 503372, 2021 Jul.
Artículo
en Inglés
| MEDLINE | ID: mdl-34266628
14.
G2/M Checkpoint Abrogation With Selective Inhibitors Results in Increased Chromatid Breaks and Radiosensitization of 82-6 hTERT and RPE Human Cells.
Front Public Health
; 9: 675095, 2021.
Artículo
en Inglés
| MEDLINE | ID: mdl-34123995
15.
NTRK1/TrkA Activation Overrides the G2/M-Checkpoint upon Irradiation.
Cancers (Basel)
; 13(23)2021 Nov 30.
Artículo
en Inglés
| MEDLINE | ID: mdl-34885133
16.
Chromosome breaks generated by low doses of ionizing radiation in G2-phase are processed exclusively by gene conversion.
DNA Repair (Amst)
; 89: 102828, 2020 05.
Artículo
en Inglés
| MEDLINE | ID: mdl-32143127
17.
A method for the cell-cycle-specific analysis of radiation-induced chromosome aberrations and breaks.
Mutat Res
; 815: 10-19, 2019 05.
Artículo
en Inglés
| MEDLINE | ID: mdl-30999232
18.
Radiation-dose-dependent functional synergisms between ATM, ATR and DNA-PKcs in checkpoint control and resection in G2-phase.
Sci Rep
; 9(1): 8255, 2019 06 04.
Artículo
en Inglés
| MEDLINE | ID: mdl-31164689
19.
DNA-PKcs and ATM epistatically suppress DNA end resection and hyperactivation of ATR-dependent G2-checkpoint in S-phase irradiated cells.
Sci Rep
; 9(1): 14597, 2019 10 10.
Artículo
en Inglés
| MEDLINE | ID: mdl-31601897
20.
DEFINED BIOLOGICAL MODELS OF HIGH-LET RADIATION LESIONS.
Radiat Prot Dosimetry
; 183(1-2): 60-68, 2019 May 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-30566664