Detalles de la búsqueda
1.
Effects of food on the pharmacokinetics of ponatinib in healthy subjects.
J Clin Pharm Ther
; 38(6): 440-4, 2013 Dec.
Artículo
en Inglés
| MEDLINE | ID: mdl-23888935
2.
Effect of Futibatinib on Cardiac Repolarization: Results of a Randomized, Controlled, Double-Blind, QT/QTc, Phase 1 Study in Healthy Subjects.
Clin Pharmacol Drug Dev
; 12(3): 304-313, 2023 03.
Artículo
en Inglés
| MEDLINE | ID: mdl-36404525
3.
Evaluation of Potential Food Effects and Drug Interactions With Lansoprazole in Healthy Adult Volunteers Receiving Futibatinib.
Clin Pharmacol Drug Dev
; 12(3): 294-303, 2023 03.
Artículo
en Inglés
| MEDLINE | ID: mdl-36382853
4.
Evaluation of the Mass Balance and Metabolic Profile of Futibatinib in Healthy Participants.
Clin Pharmacol Drug Dev
; 12(9): 927-939, 2023 09.
Artículo
en Inglés
| MEDLINE | ID: mdl-37300358
5.
Evaluation of the Cytochrome P450 3A and P-glycoprotein Drug-Drug Interaction Potential of Futibatinib.
Clin Pharmacol Drug Dev
; 12(10): 966-978, 2023 10.
Artículo
en Inglés
| MEDLINE | ID: mdl-37132707
6.
A randomized, crossover, placebo- and moxifloxacin-controlled study to evaluate the effects of bosutinib (SKI-606), a dual Src/Abl tyrosine kinase inhibitor, on cardiac repolarization in healthy adult subjects.
Int J Cancer
; 131(3): E304-11, 2012 Aug 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-22065400
7.
Pharmacokinetics of oral neratinib during co-administration of ketoconazole in healthy subjects.
Br J Clin Pharmacol
; 71(4): 522-7, 2011 Apr.
Artículo
en Inglés
| MEDLINE | ID: mdl-21395644
8.
Effects of Strong CYP2C8 or CYP3A Inhibition and CYP3A Induction on the Pharmacokinetics of Brigatinib, an Oral Anaplastic Lymphoma Kinase Inhibitor, in Healthy Volunteers.
Clin Pharmacol Drug Dev
; 9(2): 214-223, 2020 02.
Artículo
en Inglés
| MEDLINE | ID: mdl-31287236
9.
The Effect of a High-Fat Meal on the Pharmacokinetics of Brigatinib, an Oral Anaplastic Lymphoma Kinase Inhibitor, in Healthy Volunteers.
Clin Pharmacol Drug Dev
; 8(6): 734-741, 2019 08.
Artículo
en Inglés
| MEDLINE | ID: mdl-30570839
10.
Phase I clinical trial of the farnesyltransferase inhibitor BMS-214662 administered as a weekly 24 h continuous intravenous infusion in patients with advanced solid tumors.
Cancer Chemother Pharmacol
; 58(1): 107-16, 2006 Jul.
Artículo
en Inglés
| MEDLINE | ID: mdl-16362299
11.
Phase I trial and pharmacokinetic study of BMS-247550, an epothilone B analog, administered intravenously on a daily schedule for five days.
J Clin Oncol
; 21(9): 1866-73, 2003 May 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-12721265
12.
Validation of the pharmacodynamics of BMS-247550, an analogue of epothilone B, during a phase I clinical study.
Clin Cancer Res
; 8(7): 2035-43, 2002 Jul.
Artículo
en Inglés
| MEDLINE | ID: mdl-12114401
13.
A phase I study of oral BMS-275291, a novel nonhydroxamate sheddase-sparing matrix metalloproteinase inhibitor, in patients with advanced or metastatic cancer.
Clin Cancer Res
; 10(6): 1963-70, 2004 Mar 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-15041713
14.
Effect of rifampin on the pharmacokinetics of bosutinib, a dual Src/Abl tyrosine kinase inhibitor, when administered concomitantly to healthy subjects.
Drug Metab Pers Ther
; 30(1): 57-63, 2015 Mar.
Artículo
en Inglés
| MEDLINE | ID: mdl-25803093
15.
Evaluation of the effect of multiple doses of rifampin on the pharmacokinetics and safety of ponatinib in healthy subjects.
Clin Pharmacol Drug Dev
; 4(5): 354-60, 2015 09.
Artículo
en Inglés
| MEDLINE | ID: mdl-27137144
16.
A review and assessment of potential sources of ethnic differences in drug responsiveness.
J Clin Pharmacol
; 43(9): 943-67, 2003 Sep.
Artículo
en Inglés
| MEDLINE | ID: mdl-12971027
17.
Evaluation of the effect of multiple doses of lansoprazole on the pharmacokinetics and safety of ponatinib in healthy subjects.
Clin Drug Investig
; 34(10): 723-9, 2014 Oct.
Artículo
en Inglés
| MEDLINE | ID: mdl-25145453
18.
Evaluation of pharmacokinetics and safety of ponatinib in subjects with chronic hepatic impairment and matched healthy subjects.
Cancer Chemother Pharmacol
; 74(2): 341-8, 2014 Aug.
Artículo
en Inglés
| MEDLINE | ID: mdl-24934866
19.
A clinical study to examine the potential effect of lansoprazole on the pharmacokinetics of bosutinib when administered concomitantly to healthy subjects.
Clin Drug Investig
; 33(8): 589-95, 2013 Aug.
Artículo
en Inglés
| MEDLINE | ID: mdl-23839484
20.
Evaluation of the pharmacokinetics and safety of bosutinib in patients with chronic hepatic impairment and matched healthy subjects.
Cancer Chemother Pharmacol
; 71(1): 123-32, 2013 Jan.
Artículo
en Inglés
| MEDLINE | ID: mdl-23053269