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1.
A new paradigm for regulation of protein phosphatase 2A function via Src and Fyn kinase-mediated tyrosine phosphorylation.
J Biol Chem
; 298(8): 102248, 2022 08.
Artículo
en Inglés
| MEDLINE | ID: mdl-35820485
2.
Methyl donor supplementation reduces phospho-Tau, Fyn and demethylated protein phosphatase 2A levels and mitigates learning and motor deficits in a mouse model of tauopathy.
Neuropathol Appl Neurobiol
; 49(4): e12931, 2023 08.
Artículo
en Inglés
| MEDLINE | ID: mdl-37565253
3.
Disturbances in PP2A methylation and one-carbon metabolism compromise Fyn distribution, neuritogenesis, and APP regulation.
J Biol Chem
; 296: 100237, 2021.
Artículo
en Inglés
| MEDLINE | ID: mdl-33380425
4.
Assessment of evidence for or against contributions of Chlamydia pneumoniae infections to Alzheimer's disease etiology.
Brain Behav Immun
; 83: 22-32, 2020 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-31626972
5.
FAT1 cadherin controls neuritogenesis during NTera2 cell differentiation.
Biochem Biophys Res Commun
; 514(3): 625-631, 2019 06 30.
Artículo
en Inglés
| MEDLINE | ID: mdl-31076104
6.
PP2A methylation controls sensitivity and resistance to ß-amyloid-induced cognitive and electrophysiological impairments.
Proc Natl Acad Sci U S A
; 113(12): 3347-52, 2016 Mar 22.
Artículo
en Inglés
| MEDLINE | ID: mdl-26951658
7.
The protein serine/threonine phosphatases PP2A, PP1 and calcineurin: A triple threat in the regulation of the neuronal cytoskeleton.
Mol Cell Neurosci
; 84: 119-131, 2017 10.
Artículo
en Inglés
| MEDLINE | ID: mdl-28126489
8.
FAT1 cadherin acts upstream of Hippo signalling through TAZ to regulate neuronal differentiation.
Cell Mol Life Sci
; 72(23): 4653-69, 2015 Dec.
Artículo
en Inglés
| MEDLINE | ID: mdl-26104008
9.
Leucine carboxyl methyltransferase 1 (LCMT1)-dependent methylation regulates the association of protein phosphatase 2A and Tau protein with plasma membrane microdomains in neuroblastoma cells.
J Biol Chem
; 288(38): 27396-27405, 2013 Sep 20.
Artículo
en Inglés
| MEDLINE | ID: mdl-23943618
10.
Acute administration of L-DOPA induces changes in methylation metabolites, reduced protein phosphatase 2A methylation, and hyperphosphorylation of Tau protein in mouse brain.
J Neurosci
; 32(27): 9173-81, 2012 Jul 04.
Artículo
en Inglés
| MEDLINE | ID: mdl-22764226
11.
The protein phosphatase PP2A/Bα binds to the microtubule-associated proteins Tau and MAP2 at a motif also recognized by the kinase Fyn: implications for tauopathies.
J Biol Chem
; 287(18): 14984-93, 2012 Apr 27.
Artículo
en Inglés
| MEDLINE | ID: mdl-22403409
12.
A Novel Role of PP2A Methylation in the Regulation of Tight Junction Assembly and Integrity.
Front Cell Dev Biol
; 10: 911279, 2022.
Artículo
en Inglés
| MEDLINE | ID: mdl-35912112
13.
Regulation of protein phosphatase 2A methylation by LCMT1 and PME-1 plays a critical role in differentiation of neuroblastoma cells.
J Neurochem
; 115(6): 1455-65, 2010 Dec.
Artículo
en Inglés
| MEDLINE | ID: mdl-21044074
14.
PP2AC Phospho-Tyr307 Antibodies Are Not Specific for this Modification but Are Sensitive to Other PP2AC Modifications Including Leu309 Methylation.
Cell Rep
; 30(9): 3171-3182.e6, 2020 03 03.
Artículo
en Inglés
| MEDLINE | ID: mdl-32130916
15.
Folate deficiency induces in vitro and mouse brain region-specific downregulation of leucine carboxyl methyltransferase-1 and protein phosphatase 2A B(alpha) subunit expression that correlate with enhanced tau phosphorylation.
J Neurosci
; 28(45): 11477-87, 2008 Nov 05.
Artículo
en Inglés
| MEDLINE | ID: mdl-18987184
16.
Protein phosphatase 2A associates with and regulates atypical PKC and the epithelial tight junction complex.
J Cell Biol
; 158(5): 967-78, 2002 Sep 02.
Artículo
en Inglés
| MEDLINE | ID: mdl-12196510
17.
Protein Phosphatase 2A: More Than a Passenger in the Regulation of Epithelial Cell-Cell Junctions.
Front Cell Dev Biol
; 7: 30, 2019.
Artículo
en Inglés
| MEDLINE | ID: mdl-30895176
18.
Protein phosphatase 2A methyltransferase links homocysteine metabolism with tau and amyloid precursor protein regulation.
J Neurosci
; 27(11): 2751-9, 2007 Mar 14.
Artículo
en Inglés
| MEDLINE | ID: mdl-17360897
19.
Protein phosphatase 2A and tau: an orchestrated 'Pas de Deux'.
FEBS Lett
; 592(7): 1079-1095, 2018 04.
Artículo
en Inglés
| MEDLINE | ID: mdl-29121398
20.
Methylenetetrahydrofolate Reductase Deficiency Deregulates Regional Brain Amyloid-ß Protein Precursor Expression and Phosphorylation Levels.
J Alzheimers Dis
; 64(1): 223-237, 2018.
Artículo
en Inglés
| MEDLINE | ID: mdl-29865064