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1.
Fragment-based design, synthesis, biological evaluation, and SAR of 1H-benzo[d]imidazol-2-yl)-1H-indazol derivatives as potent PDK1 inhibitors.
Bioorg Med Chem Lett
; 27(24): 5473-5480, 2017 12 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-29150397
2.
Reversible inhibition of lysine specific demethylase 1 is a novel anti-tumor strategy for poorly differentiated endometrial carcinoma.
BMC Cancer
; 14: 752, 2014 Oct 09.
Artículo
en Inglés
| MEDLINE | ID: mdl-25300887
3.
Design, Synthesis, and Biological Evaluation of a Series of Anthracene-9,10-dione Dioxime ß-Catenin Pathway Inhibitors.
J Med Chem
; 58(15): 5854-62, 2015 Aug 13.
Artículo
en Inglés
| MEDLINE | ID: mdl-26182238
4.
Reversible LSD1 inhibition interferes with global EWS/ETS transcriptional activity and impedes Ewing sarcoma tumor growth.
Clin Cancer Res
; 20(17): 4584-97, 2014 Sep 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-24963049
5.
Synthesis and assessment of glycosaminoglycan priming activity of cluster-xylosides for potential use as proteoglycan mimetics.
ACS Chem Biol
; 8(5): 949-57, 2013 May 17.
Artículo
en Inglés
| MEDLINE | ID: mdl-23402705
6.
High-throughput virtual screening identifies novel N'-(1-phenylethylidene)-benzohydrazides as potent, specific, and reversible LSD1 inhibitors.
J Med Chem
; 56(23): 9496-508, 2013 Dec 12.
Artículo
en Inglés
| MEDLINE | ID: mdl-24237195
7.
Dimerized glycosaminoglycan chains increase FGF signaling during zebrafish development.
ACS Chem Biol
; 8(5): 939-48, 2013 May 17.
Artículo
en Inglés
| MEDLINE | ID: mdl-23614643
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