Detalles de la búsqueda
1.
Rosmarinus officinalis L. Leaf Extracts and Their Metabolites Inhibit the Aryl Hydrocarbon Receptor (AhR) Activation In Vitro and in Human Keratinocytes: Potential Impact on Inflammatory Skin Diseases and Skin Cancer.
Molecules
; 27(8)2022 Apr 13.
Artículo
en Inglés
| MEDLINE | ID: mdl-35458697
2.
Structure-based virtual screening of perfluoroalkyl and polyfluoroalkyl substances (PFASs) as endocrine disruptors of androgen receptor activity using molecular docking and machine learning.
Environ Res
; 190: 109920, 2020 11.
Artículo
en Inglés
| MEDLINE | ID: mdl-32795691
3.
Transitional States in Ligand-Dependent Transformation of the Aryl Hydrocarbon Receptor into Its DNA-Binding Form.
Int J Mol Sci
; 21(7)2020 Apr 02.
Artículo
en Inglés
| MEDLINE | ID: mdl-32252465
4.
Carcinogenicity of perfluorooctanoic acid and perfluorooctanesulfonic acid.
Lancet Oncol
; 25(1): 16-17, 2024 Jan.
Artículo
en Inglés
| MEDLINE | ID: mdl-38043561
5.
Vemurafenib acts as an aryl hydrocarbon receptor antagonist: Implications for inflammatory cutaneous adverse events.
Allergy
; 74(12): 2437-2448, 2019 12.
Artículo
en Inglés
| MEDLINE | ID: mdl-31269229
6.
Comparative In Vitro and In Silico Analysis of the Selectivity of Indirubin as a Human Ah Receptor Agonist.
Int J Mol Sci
; 19(9)2018 Sep 10.
Artículo
en Inglés
| MEDLINE | ID: mdl-30201897
7.
Deciphering Dimerization Modes of PAS Domains: Computational and Experimental Analyses of the AhR:ARNT Complex Reveal New Insights Into the Mechanisms of AhR Transformation.
PLoS Comput Biol
; 12(6): e1004981, 2016 06.
Artículo
en Inglés
| MEDLINE | ID: mdl-27295348
8.
Auto-induction mechanism of aryl hydrocarbon receptor 2 (AHR2) gene by TCDD-activated AHR1 and AHR2 in the red seabream (Pagrus major).
Arch Toxicol
; 91(1): 301-312, 2017 Jan.
Artículo
en Inglés
| MEDLINE | ID: mdl-27188387
9.
Metformin inhibits 7,12-dimethylbenz[a]anthracene-induced breast carcinogenesis and adduct formation in human breast cells by inhibiting the cytochrome P4501A1/aryl hydrocarbon receptor signaling pathway.
Toxicol Appl Pharmacol
; 284(2): 217-26, 2015 Apr 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-25697376
10.
Pityriazepin and other potent AhR ligands isolated from Malassezia furfur yeast.
Arch Biochem Biophys
; 571: 16-20, 2015 Apr 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-25721496
11.
Activation of the aryl hydrocarbon receptor by the widely used Src family kinase inhibitor 4-amino-5-(4-chlorophenyl)-7-(dimethylethyl)pyrazolo[3,4-d]pyrimidine (PP2).
Arch Toxicol
; 89(8): 1329-36, 2015 Aug.
Artículo
en Inglés
| MEDLINE | ID: mdl-25082669
12.
Comparative analysis of homology models of the AH receptor ligand binding domain: verification of structure-function predictions by site-directed mutagenesis of a nonfunctional receptor.
Biochemistry
; 52(4): 714-25, 2013 Jan 29.
Artículo
en Inglés
| MEDLINE | ID: mdl-23286227
13.
2,3-cis-2R,3R-(-)-epiafzelechin-3-O-p-coumarate, a novel flavan-3-ol isolated from Fallopia convolvulus seed, is an estrogen receptor agonist in human cell lines.
BMC Complement Altern Med
; 13: 133, 2013 Jun 14.
Artículo
en Inglés
| MEDLINE | ID: mdl-23768005
14.
A novel prenylflavone restricts breast cancer cell growth through AhR-mediated destabilization of ERα protein.
Carcinogenesis
; 33(5): 1089-97, 2012 May.
Artículo
en Inglés
| MEDLINE | ID: mdl-22345291
15.
Ligand displaces heat shock protein 90 from overlapping binding sites within the aryl hydrocarbon receptor ligand-binding domain.
J Biol Chem
; 286(40): 35275-82, 2011 Oct 07.
Artículo
en Inglés
| MEDLINE | ID: mdl-21856752
16.
Modeling the transplacental transfer of small molecules using machine learning: a case study on per- and polyfluorinated substances (PFAS).
J Expo Sci Environ Epidemiol
; 32(6): 808-819, 2022 11.
Artículo
en Inglés
| MEDLINE | ID: mdl-36207486
17.
The p38 MAPK inhibitor SB203580 induces cytochrome P450 1A1 gene expression in murine and human hepatoma cell lines through ligand-dependent aryl hydrocarbon receptor activation.
Chem Res Toxicol
; 24(9): 1540-8, 2011 Sep 19.
Artículo
en Inglés
| MEDLINE | ID: mdl-21732638
18.
New aryl hydrocarbon receptor homology model targeted to improve docking reliability.
J Chem Inf Model
; 51(11): 2868-81, 2011 Nov 28.
Artículo
en Inglés
| MEDLINE | ID: mdl-21981577
19.
Detection of the TCDD binding-fingerprint within the Ah receptor ligand binding domain by structurally driven mutagenesis and functional analysis.
Biochemistry
; 48(25): 5972-83, 2009 Jun 30.
Artículo
en Inglés
| MEDLINE | ID: mdl-19456125
20.
Sustained activation of the Aryl hydrocarbon Receptor transcription factor promotes resistance to BRAF-inhibitors in melanoma.
Nat Commun
; 9(1): 4775, 2018 11 14.
Artículo
en Inglés
| MEDLINE | ID: mdl-30429474