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1.
Universal Automated Immunoaffinity Purification-CE-MS Platform for Accelerating Next Generation Biologic Design.
Anal Chem
; 93(13): 5562-5569, 2021 04 06.
Artículo
en Inglés
| MEDLINE | ID: mdl-33764735
2.
Pharmacological Assessment of Sepiapterin Reductase Inhibition on Tactile Response in the Rat.
J Pharmacol Exp Ther
; 371(2): 476-486, 2019 11.
Artículo
en Inglés
| MEDLINE | ID: mdl-31110114
3.
Use of Cryopreserved Hepatocytes as Part of an Integrated Strategy to Characterize In Vivo Clearance for Peptide-Antibody Conjugate Inhibitors of Nav1.7 in Preclinical Species.
Drug Metab Dispos
; 47(10): 1111-1121, 2019 10.
Artículo
en Inglés
| MEDLINE | ID: mdl-31387871
4.
Immunoaffinity capture coupled with capillary electrophoresis - mass spectrometry to study therapeutic protein stability in vivo.
Anal Biochem
; 539: 118-126, 2017 12 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-29029979
5.
Nonclinical Pharmacokinetics, Disposition, and Drug-Drug Interaction Potential of a Novel d-Amino Acid Peptide Agonist of the Calcium-Sensing Receptor AMG 416 (Etelcalcetide).
Drug Metab Dispos
; 44(8): 1319-31, 2016 08.
Artículo
en Inglés
| MEDLINE | ID: mdl-26895981
6.
Utility of physiologically based pharmacokinetic modeling to predict inter-antibody variability in monoclonal antibody pharmacokinetics in mice.
MAbs
; 15(1): 2263926, 2023.
Artículo
en Inglés
| MEDLINE | ID: mdl-37824334
7.
Attenuated IL-2 muteins leverage the TCR signal to enhance regulatory T cell homeostasis and response in vivo.
Front Immunol
; 14: 1257652, 2023.
Artículo
en Inglés
| MEDLINE | ID: mdl-37809101
8.
Investigation of the mechanism of clearance of AMG 386, a selective angiopoietin-1/2 neutralizing peptibody, in splenectomized, nephrectomized, and FcRn knockout rodent models.
Pharm Res
; 29(4): 1057-65, 2012 Apr.
Artículo
en Inglés
| MEDLINE | ID: mdl-22189693
9.
A Non-radiometric Approach to Determine Tissue Vascular Blood Volume in Biodistribution Studies.
AAPS J
; 24(6): 116, 2022 11 14.
Artículo
en Inglés
| MEDLINE | ID: mdl-36376552
10.
Development of an immunoassay for aglycosylated murine IgG1 in mouse serum via generation of a specific tool antibody.
Bioanalysis
; 14(9): 581-588, 2022 May.
Artículo
en Inglés
| MEDLINE | ID: mdl-35548877
11.
Preclinical characterization of the ADME properties of a surrogate anti-IL-36R monoclonal antibody antagonist in mouse serum and tissues.
MAbs
; 12(1): 1746520, 2020.
Artículo
en Inglés
| MEDLINE | ID: mdl-32310023
12.
Pharmacokinetic comparison of a diverse panel of non-targeting human antibodies as matched IgG1 and IgG2 isotypes in rodents and non-human primates.
PLoS One
; 14(5): e0217061, 2019.
Artículo
en Inglés
| MEDLINE | ID: mdl-31120944
13.
Engineering NaV1.7 Inhibitory JzTx-V Peptides with a Potency and Basicity Profile Suitable for Antibody Conjugation To Enhance Pharmacokinetics.
ACS Chem Biol
; 14(4): 806-818, 2019 04 19.
Artículo
en Inglés
| MEDLINE | ID: mdl-30875193
14.
Engineering Antibody Reactivity for Efficient Derivatization to Generate NaV1.7 Inhibitory GpTx-1 Peptide-Antibody Conjugates.
ACS Chem Biol
; 12(9): 2427-2435, 2017 09 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-28800217
15.
Evaluation of matrix microsampling methods for therapeutic drug candidate quantification in discovery-stage rodent pharmacokinetic studies.
Bioanalysis
; 6(16): 2135-46, 2014 Aug.
Artículo
en Inglés
| MEDLINE | ID: mdl-25331858
16.
Measurement of in vivo therapeutic mAb concentrations: comparison of conventional serum/plasma collection and analysis to dried blood spot sampling.
Bioanalysis
; 5(16): 1979-90, 2013 Aug.
Artículo
en Inglés
| MEDLINE | ID: mdl-23937133
17.
Application of DBS sampling in combination with LC-MS/MS for pharmacokinetic evaluation of a compound with species-specific blood-to-plasma partitioning.
Bioanalysis
; 4(16): 2037-47, 2012 Aug.
Artículo
en Inglés
| MEDLINE | ID: mdl-22946919
18.
Application of automated serial blood sampling and dried blood spot technique with liquid chromatography-tandem mass spectrometry for pharmacokinetic studies in mice.
J Pharm Biomed Anal
; 56(3): 604-8, 2011 Nov 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-21784595
19.
Application of automated dried blood spot sampling and LC-MS/MS for pharmacokinetic studies of AMG 517 in rats.
Bioanalysis
; 3(20): 2349-56, 2011 Oct.
Artículo
en Inglés
| MEDLINE | ID: mdl-22011182
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