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1.
3,5-Disubstituted indole derivatives as selective human neuronal nitric oxide synthase (nNOS) inhibitors.
Bioorg Med Chem Lett
; 22(5): 1980-4, 2012 Mar 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-22318159
2.
1,5-Disubstituted indole derivatives as selective human neuronal nitric oxide synthase inhibitors.
Bioorg Med Chem Lett
; 21(18): 5301-4, 2011 Sep 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-21813276
3.
1,6-Disubstituted indole derivatives as selective human neuronal nitric oxide synthase inhibitors.
Bioorg Med Chem Lett
; 21(18): 5234-8, 2011 Sep 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-21824773
4.
1,2,3,4-tetrahydroquinoline-based selective human neuronal nitric oxide synthase (nNOS) inhibitors: lead optimization studies resulting in the identification of N-(1-(2-(methylamino)ethyl)-1,2,3,4-tetrahydroquinolin-6-yl)thiophene-2-carboximidamide as a preclinical development candidate.
J Med Chem
; 55(6): 2882-93, 2012 Mar 22.
Artículo
en Inglés
| MEDLINE | ID: mdl-22335555
5.
Design, synthesis, and biological evaluation of 3,4-dihydroquinolin-2(1H)-one and 1,2,3,4-tetrahydroquinoline-based selective human neuronal nitric oxide synthase (nNOS) inhibitors.
J Med Chem
; 54(15): 5562-75, 2011 Aug 11.
Artículo
en Inglés
| MEDLINE | ID: mdl-21699209
6.
Safety and pharmacokinetics of NXN-188 after single and multiple doses in five phase I, randomized, double-blind, parallel studies in healthy adult volunteers.
Clin Ther
; 32(1): 146-60, 2010 Jan.
Artículo
en Inglés
| MEDLINE | ID: mdl-20171420
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