Detalles de la búsqueda
1.
Population pharmacokinetics and pharmacodynamics of efmarodocokin alfa (IL-22Fc).
J Pharmacokinet Pharmacodyn
; 51(2): 141-153, 2024 Apr.
Artículo
en Inglés
| MEDLINE | ID: mdl-37864000
2.
Evaluation of the reproducibility of responses to nasal allergen challenge and effects of inhaled nasal corticosteroids.
Clin Exp Allergy
; 53(11): 1187-1197, 2023 11.
Artículo
en Inglés
| MEDLINE | ID: mdl-37794659
3.
Expanding assay range to accommodate a monoclonal antibody therapeutic quantification in blood and cerebrospinal fluid.
Bioanalysis
; 16(3): 129-140, 2024 Feb.
Artículo
en Inglés
| MEDLINE | ID: mdl-38088824
4.
Sialic Acid Mediated Endothelial and Hepatic Uptake: A Mechanism based Mathematic Model Elucidating the Complex Pharmacokinetics and Pharmacodynamics of Efmarodocokin Alfa, a Variably Glycosylated Fusion Protein.
J Pharm Sci
; 113(7): 1975-1986, 2024 Jul.
Artículo
en Inglés
| MEDLINE | ID: mdl-38561054
5.
Evaluation of multiple immunoassay formats for detection of anti-drug antibodies to zinpentraxin alfa.
J Immunol Methods
; 522: 113573, 2023 11.
Artículo
en Inglés
| MEDLINE | ID: mdl-37816404
6.
Factors contributing to the nonlinear pharmacokinetics of astegolimab: a close examination of potential causes.
Bioanalysis
; 15(21): 1305-1314, 2023 Nov.
Artículo
en Inglés
| MEDLINE | ID: mdl-37791725
7.
The Development and Characterization of a Highly Sensitive Mature TGFß3 Assay to Evaluate Anti-TGFß3 Target Engagement.
AAPS J
; 25(1): 21, 2023 01 26.
Artículo
en Inglés
| MEDLINE | ID: mdl-36703086
8.
Mini-PBPK-Based Population Model and Covariate Analysis to Assess the Complex Pharmacokinetics and Pharmacodynamics of RO7449135, an Anti-KLK5/KLK7 Bispecific Antibody in Cynomolgus Monkeys.
AAPS J
; 25(4): 64, 2023 06 23.
Artículo
en Inglés
| MEDLINE | ID: mdl-37353723
9.
Challenges with development of a pharmacokinetics assay to measure a variably glycosylated fusion protein.
Bioanalysis
; 14(1): 7-18, 2022 Jan.
Artículo
en Inglés
| MEDLINE | ID: mdl-34789009
10.
Population Pharmacokinetics and Exposure-Response Relationships of Astegolimab in Patients With Severe Asthma.
J Clin Pharmacol
; 62(7): 905-917, 2022 07.
Artículo
en Inglés
| MEDLINE | ID: mdl-34964491
11.
Population pharmacokinetic analysis of etrolizumab in patients with moderately-to-severely active ulcerative colitis.
CPT Pharmacometrics Syst Pharmacol
; 11(9): 1244-1255, 2022 09.
Artículo
en Inglés
| MEDLINE | ID: mdl-35851998
12.
Dose-dependent inactivation of airway tryptase with a novel dissociating anti-tryptase antibody (MTPS9579A) in healthy participants: A randomized trial.
Clin Transl Sci
; 15(2): 451-463, 2022 02.
Artículo
en Inglés
| MEDLINE | ID: mdl-34581002
13.
2021 White Paper on Recent Issues in Bioanalysis: ISR for Biomarkers, Liquid Biopsies, Spectral Cytometry, Inhalation/Oral & Multispecific Biotherapeutics, Accuracy/LLOQ for Flow Cytometry (Part 2 - Recommendations on Biomarkers/CDx Assays Development & Validation, Cytometry Validation & Innovation, Biotherapeutics PK LBA Regulated Bioanalysis, Critical Reagents & Positive Controls Generation).
Bioanalysis
; 14(10): 627-692, 2022 May.
Artículo
en Inglés
| MEDLINE | ID: mdl-35578974
14.
Potent high-affinity antibodies for treatment and prophylaxis of respiratory syncytial virus derived from B cells of infected patients.
J Immunol
; 183(10): 6338-45, 2009 Nov 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-19841167
15.
Clinical Immunogenicity Risk Assessment for a Fusion Protein.
AAPS J
; 22(3): 64, 2020 04 03.
Artículo
en Inglés
| MEDLINE | ID: mdl-32246297
16.
Clinical Immunogenicity Risk Assessment Strategy for a Low Risk Monoclonal Antibody.
AAPS J
; 22(3): 60, 2020 03 17.
Artículo
en Inglés
| MEDLINE | ID: mdl-32185565
17.
Development of a specific immunoassay to selectively measure active tryptase in airway samples.
Bioanalysis
; 12(19): 1377-1388, 2020 Oct.
Artículo
en Inglés
| MEDLINE | ID: mdl-32975431
18.
Antibody discovery via multiplexed single cell characterization.
J Immunol Methods
; 341(1-2): 135-45, 2009 Feb 28.
Artículo
en Inglés
| MEDLINE | ID: mdl-19087879
19.
Bioanalytical challenges in development of ultrasensitive Home Brew assays: a case study using IL-13.
Bioanalysis
; 11(11): 1045-1054, 2019 Jun.
Artículo
en Inglés
| MEDLINE | ID: mdl-31251105
20.
An in vitro FcRn- dependent transcytosis assay as a screening tool for predictive assessment of nonspecific clearance of antibody therapeutics in humans.
MAbs
; 11(5): 942-955, 2019 07.
Artículo
en Inglés
| MEDLINE | ID: mdl-30982394